Vocab chp 15

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46 Terms

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Operator

A DNA region in prokaryotic operons that controls the access of RNA polymerase to genes.

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Operon

A cluster of genes in prokaryotes that are regulated together, typically involved in a related function.

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Repressor

A protein that binds to the operator and blocks transcription.

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Regulatory Gene

A gene that produces a repressor or activator to regulate the expression of another gene.

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Corepressor

A molecule that binds to a repressor, enhancing its ability to inhibit transcription.

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Inducer

A molecule that binds to a repressor, preventing it from binding to the operator and allowing gene transcription.

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Activator

A protein that increases the transcription of a gene by binding to its regulatory region.

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Differential Gene Expression

The process by which different genes are expressed in different cells, leading to cell differentiation.

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Histone Acetylation

The addition of acetyl groups to histones, relaxing chromatin and increasing gene expression.

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DNA Methylation

The addition of methyl groups to DNA, typically silencing gene expression.

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Epigenetic Inheritance

The transmission of gene expression patterns through generations without changes in the underlying DNA sequence.

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Control Elements

DNA sequences that regulate gene expression by interacting with transcription factors.

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Enhancers

DNA sequences that increase the rate of transcription by attracting transcription factors.

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Alternative RNA Splicing

A process by which different combinations of exons are spliced together, allowing one gene to produce multiple mRNA variants.

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microRNAs (miRNA)

Small RNA molecules that regulate gene expression by binding to mRNA and preventing its translation.

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Small Interfering RNAs (siRNA)

Small RNA molecules that promote the degradation of mRNA or inhibit its translation.

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Nucleic Acid Hybridization

The process of combining complementary strands of nucleic acids.

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Nucleic Acid Probe

A labeled single-stranded nucleic acid used to detect complementary sequences in DNA or RNA.

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In Situ Hybridization

A technique used to detect specific nucleic acid sequences within cells or tissues.

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Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR)

A technique that converts RNA into complementary DNA (cDNA) and amplifies it to study gene expression.

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Complementary DNA (cDNA)

DNA synthesized from an RNA template by reverse transcription.

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DNA Microarray Assays

A technique used to measure the expression of many genes simultaneously.

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Model Organisms

Organisms that are used to study biological processes and that are easily manipulated in laboratory settings.

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Differentiation

The process by which cells become specialized in structure and function.

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Morphogenesis

The process by which cells and tissues develop into specific structures during embryonic development.

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Homeotic Genes

Genes that control the development of body structures in specific regions of the embryo.

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Stem Cells

Undifferentiated cells capable of differentiating into various specialized cell types.

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Totipotent

Stem cells that have the potential to differentiate into any cell type, including the entire organism.

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Pluripotent

Stem cells that can differentiate into any cell type but cannot form an entire organism.

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Virus

A microscopic infectious agent that requires a host cell to replicate.

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Capsid

The protein shell of a virus that encases its genetic material.

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Viral Envelope

A lipid bilayer membrane that surrounds some viruses, derived from the host cell membrane.

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Phages

Viruses that infect bacteria.

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Lytic Cycle

A viral replication cycle in which the host cell is destroyed after virus production.

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Virulent Phage

A phage that only follows the lytic cycle and kills the host cell.

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Lysogenic Cycle

A viral replication cycle where the virus integrates into the host's genome and can remain dormant.

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Prophage

A phage genome integrated into the bacterial host genome during the lysogenic cycle.

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Restriction Enzymes

Proteins that cut DNA at specific sequences, used by bacteria as a defense mechanism against viruses.

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Retroviruses

Viruses that use reverse transcriptase to convert their RNA genome into DNA.

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Reverse Transcriptase

An enzyme used by retroviruses to synthesize DNA from RNA.

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Genomics

The study of the structure, function, evolution, and mapping of genomes.

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Bioinformatics

The use of computational tools to analyze and interpret biological data, especially genomic data.

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Transposable Elements

DNA sequences that can move or 'transpose' to different locations within the genome.

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Short Tandem Repeats (STR)

Repeated sequences of 2-6 base pairs of DNA used in DNA profiling.

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Single Nucleotide Polymorphisms (SNPs)

Variations at a single nucleotide position in DNA among individuals.

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Homeobox

A DNA sequence found in many genes involved in regulating development, particularly in controlling body plan formation.