Non-Sterile Compounding Practice Exam

A set of 200 fill-in-the-blank practice flashcards covering non-sterile compounding topics including equipment, techniques, and preparation types based on the lecture notes.

Non-sterile compounding is the __________ formulation of a prescribed drug.

on-site

Compounding is performed to meet the __________ needs of a patient.

unique

An example of compounding is the __________ of amoxicillin.

constituting

Liquid formulations can be adjusted by adding __________ for children and adults.

flavor

The demand for compounding is growing due to the expansion of __________ health care.

home

Compounding is necessary when there is an __________ of certain drug products.

unavailability

A growing area for pharmaceutical compounding is __________ compounding.

veterinary

Pharmacy technicians involved in compounding work under the close __________ of a pharmacist.

supervision

Compounding covers preparations like suspensions, __________, and suppositories.

dermatologicals

Compounded preparations include converting one __________ __________ into another.

dosage form

Syringes and __________ __________ are examples of compounding preparations mentioned.

parenteral nutrition

USP-NF stands for the United States Pharmacopoeia and __________ __________.

National Formulary

USP-NF establishes standards for quality, strength, purity, __________, and labeling.

packaging

The USP defines __________ and equipment specifications for compounding.

compounding

USP Chapter __________ sets legal standards for non-sterile compounding.

$$795$$

USP Chapter __________ sets legal standards for sterile compounding.

$$797$$

The USP-NF is a __________ organization.

nonprofit

USP-NF has been granted __________ authority to set standards for manufacturing and compounding.

federal

Equipment overview includes measuring balance weights and __________ containers.

weighing

Graduated cylinders and volumetric flasks are types of __________ glassware.

volumetric

Mixing equipment include beakers, __________, and spatulas.

flasks

A __________ and pestle is commonly used for mixing solids and semi-solids.

mortar

__________ plates and suppository moulds are used for molding.

Hot

Prescription bottles and capsule vials are types of __________ equipment.

packaging

Ointment jars and __________ boxes are used for packaging compounded items.

suppository

Volumetric glassware is used to measure liquid drugs, __________, and additives.

solvents

The best choices for measuring and transferring liquids are graduated cylinders and __________ __________.

volumetric flasks

__________ are good for measuring exact volume for adding additives into PN preparations.

Syringes

Syringes are used to remove excess volumes and __________ __________ from preparations.

air bubbles

When measuring liquids, you should always use the __________ device.

smallest

To be precise with a graduated cylinder, you must get at __________ __________ to the cylinder.

eye level

If an order calls for $30\,ml$ of fluid, you should use a __________ syringe.

$$30\,ml$$

Using a $60\,ml$ syringe to measure $30\,ml$ is considered a __________ of the syringe.

waste

There are __________ common types of mortar and pestle materials.

three

__________ mortars and pestles are used for liquids and semi-solid dosage forms.

Glass

Glass mortars help achieve a __________ consistency in preparations.

smooth

__________ mortars and pestles are used to grind crystals into fine powders.

Wedgewood

__________ mortars and pestles are used to grind large particles into fine powders.

Porcelain

__________ help produce fine particles by excluding those larger than the mesh opening.

Sieves

A sieve only allows particles __________ than the mesh opening to pass through.

smaller

__________ __________ is a process where a small amount of powder is diluted in steps.

Geometric dilution

Geometric dilution involves additions of __________ amounts of powder.

larger

__________ is the process of grinding powders to reduce particle size.

Trituration

Without trituration, a __________ mixture will not result.

homogeneous

A homogeneous mixture is defined as being __________ and __________ combined.

fully; evenly

A __________ agent or diluting agent can be added during mixing to help blend.

wetting

__________ are used to transfer solid ingredients and mix semi-solids like creams.

Spatulas

Spatulas can be made of stainless steel, __________, or plastic.

hard rubber

__________ is the process of mixing powders using spatulas.

Spatulation

Spatulation is helpful for mixing powders that can form __________ powders.

eutectic

Ointments and creams may be prepared on __________ __________.

ointment slabs

Ointment slabs are plates made of porcelain or __________ __________.

ground glass

__________ is a technique used to reduce particle size by triturating with a solvent.

Levigation

In levigation, the ingredient must be __________ in the solvent used.

insoluble

Levigation is used to reduce the __________ of the final preparation.

grittiness

An example of levigation is hydrocortisone levigated with __________.

glycerin

Hot plates are useful for __________ solids or semi-solids to allow mixing.

melting

EMP stands for __________ __________ __________ __________.

electronic mortar and pestle

An __________ mortar and pestle can be used to blend large quantities of powders.

electronic

An __________ __________ help achieve very uniform particle sizes in topicals.

ointment mill

Ointment mills provide uniform particle sizes for topical, rectal, and __________ preparations.

oral

__________ are the most commonly compounded preparations.

Solutions

Solutions are __________ liquids in which the drug is completely dissolved.

clear

The liquid base solution to which a drug is added is called the __________.

vehicle

Common vehicles for solutions include purified water, ethanol, and __________.

glycerine

Some solutions need to be __________, which applies sound waves.

sonified

Sonic mixing equipment uses __________ __________ to mix solutions.

sound waves

A __________ is a concentrated or nearly saturated solution of sucrose and water.

syrup

Syrups that contain flavoring agents but no drug are known as __________ __________.

flavoring syrups

An example of a flavoring syrup is __________ syrup.

cherry

Syrups containing drugs are known as __________ syrups.

medicinal

__________ syrup is an example of a medicinal syrup.

Guiatessen

Syrups can be made with or without the use of __________.

heat

Using heat to make syrup is __________, but cannot be used for heat-sensitive ingredients.

faster

Heat should not be used in syrup preparation if ingredients are __________ __________.

heat sensitive

Non-aqueous solutions contain solvents other than __________.

water

Elixirs and __________ are examples of non-aqueous solutions.

tinctures

__________ and fluid extracts are types of non-aqueous preparations.

Spirits

Glycerine, collodion, and __________ are examples of non-aqueous solutions.

liniments

__________ solutions are non-aqueous solutions.

Oleaginous

A __________ is a two-phase system consisting of a solid dispersed in a liquid.

suspension

In a suspension, the solid is __________ __________.

finely divided

The primary concern with suspensions is that they tend to __________ over time.

settle

Settling in a suspension causes the dose to become __________ dispersed.

unevenly

Settling properties of a suspension are controlled by __________ agents.

flocculating

Flocculating agents enhance particle __________.

dispersibility

__________ agents are used to reduce the sedimentation rate in suspensions.

Thickening

Another term for settling rate is __________ rate.

sedimentation

Patients generally prefer medications with flavoring that has immediate flavor __________.

recognition

Flavoring should have __________ full flavor development.

rapid

Flavoring should have an acceptable __________ and a short aftertaste.

mouthfeel

Sweeteners and __________ agents are applied to enhance the product.

coloring

An __________ is an unstable system consisting of at least two immiscible liquids.

emulsion

One liquid in an emulsion is dispersed as small __________ throughout the other.

droplets

Emulsions require a __________ agent to remain stable.

stabilizing

__________ are the agents used to stabilize emulsions.

Emulsifiers

Without stabilization, emulsions separate into two distinct __________ over time.

phases

This system is called an o/w emulsion when oil is dispersed in __________.

water

In an o/w emulsion, the aqueous solution makes up greater than __________ of the weight.

$$45\%$$

A __________ emulsifier must be used in an oil and water emulsion.

hydrophilic