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when is anxiety considered an illness
when pt is overwhelmed to point that daily functioning is impaired
pairing of a stimulus that evokes a response with a neutral environmental object or event. repeated pairing of two stimuli would lead to ability of conditioned stimulus to elicit same response as unconditioned stimulus. this type of conditioning is
classical conditioning apart of the learning theory
views stimuli as series of either positive or negative events that influence behavior. there is both positive and negative reinforcement, where positive is a particular behavior that results in a reward and negative is where a certain behavior results in a bad event.
operant conditioning apart of the learning theory
this dz is more common in women than in en. its a panic related phenomenon like isolated panic attacks, limited sx attacks. Can be apparent in childhood and misdiagnosed as a conduct disorder
Panic disorder
what anxiety disorder has the strongest family linked history
panic disorder
pt has recurrent, spontaneous, unexpected anxiety attacks with rapid onset and short duration. Pt thinks that bc they feel like this that they’re having an MI or CVA. pt needs at least 4 of the following sx: SOB, tachypnea, tachycardia, tremor, dizziness, hot/cold sensations, chest discomfort. rapid onset of sx and max severity lasts about 10 mins. this d/o is
panic d/o
panic attacks can last for how long
10 minutes with quick onset
what can happen if panic attacks are left untreated
pt won’t want to leave their house in fear of having a panic attack outside of their home, leading to agoraphobia
pt notices that certain situations cause them panic so they avoid those situations. they find safe places like their home or with safe people like a spouse or parent.
agoraphobia
if you give a pt with panic d/o OR with a + FHx CO2 what happens
they have greater anxiety responses than in people with no hx
what makes panic disorder different than other disorders
spontaneous panic attacks
how to tx panic disorder
mild = psychotherapy. if functional impairment (agoraphobic, MD/personality d/o, suicidal, pt wants) = meds like TCAs (imipramine amitriptyline, clomipramine, rarely used), MAOIs like phenelzine (rarely used bc causes HTN), SSRIs/SNRIs (paroxetine, sertraline, venlafaxine, STANDARD), low dose benzos (alprazolam and clonazepam. also CBT, pts see relationship b/w thoughts and anxiety they produce and realize the relationship b/w in/external cues and their anxiety
benzos to tx panic disorder should be avoided in pts with what h/o
alc/drug abuse
pt has an intense irrational fear to a certain object or situation other than a social situation. ex are animals/insects, natural environment, blood or infection, or situations like heights, flying, roller coasters. this d/o is
specific phobia
this d/o is characterized by extreme anxiety i\n response to situations where the person can be seen by others. fear they will act in an embarrassing or humiliating way. social situations are avoided or endured with a lot of anxiety.
social phobia
what makes phobic disorder different than other diseases
restricted to a certain object or situation.
how to tx phobic d/o
psychotherapy, benzos to reduce anxiety, BB like propranolol can be used to reduce autonomic hyperarousal. antidepressants like SSRIs
what is the treatment of choice for phobic d/o
behavioral or CBT psychotherapy. relaxation training, visualizing phobias to desensitize thru exposure.
complications of phobic d/o
occasionally disabling, behavioral tx can produce anxiety but yield results
this disorder is slightly more common in women, usually chronic. seen more in general medical practice than in psychiatry practice. constant worry of variable severity across time. also can get MDD
GAD
pt has constant worry with hyperarousal. they are restless, wound-up, easily fatigued, can’t concentrate, irritable, has muscle tension, hard to control feelings of worry. this dz is
GAD
how to tx GAD
benzos, used for sx control not to cure
adverse effects of benzodiazepines
daytime sedation, ataxia, accident prone, memory bad
what drug can be abused to counteract adverse effects of psychostimulants like cocaine, augment euphoric effects of other sedatives like alcohol, OR self medicate alcohol withdrawal. pts can get a physiologic dependence
benzos
pt has just been given an SSRI but they still have really bad sx. what else do you give them short term to hold them off until the effects of the SSRI kick in?
benzos
this drug is really similar to benzos. its a 5-HT1A partial agonist and anxiolytic. it doesn’t cause any motor, memory, or concentration imapirments, as well as no abuse potential, dependency or withdrawal from it. its an ideal anxiolytic but it takes 3 wks to show its effects. what is the drug
buspirone
what other meds besides buspirone can you take for GAD
TCA like imipramine, SNRI like venlafaxine. BB like clonidine. antipsychotics dec anxiety but cause TD which is bad. if you’re going to switch meds wait 2 weeks to avoid serotonin syndrome
how does psychotherapy help GAD
behavioral therapy to teach muscle relaxation, CBT to break down self distortions and misinterpretations of events.
complications of GAD are
co morbid with MD, personality disorder, or other anxiety d/o like OCD and panic d/o. always look for other co morbid d/o when a pt has GAD
pt has a hx of trauma like sexual assault, mass political conflict, displacement, military combat, physical injury. pts may also have dissociative sx like depersonalization and derealization these pts see a traumatic situation of threatening or out of their control, which develops trauma related psychopathology then creating fear structures. you can also link amygdala hyperactivity and dorsal anterior cingulate cortex with inc fear response leading to this dz.
PTSD
what are some things that can protect you against PTSD episodes
optimism, humor, social support, active coping style. openness to change and extraversion allows for growth after a traumatic event.
must have exposure to a real or threatened death, injury, or sexual violence in one or more of the following ways: direct exposure, witnessing trauma, learning about a close person being exposure, indirect exposure to distressing details of traumatic event. this is NOT including exposure thru digital media
criterion A to diagnose PTSD
criterion a for ptsd is
stressor
presence of one or more sx related to the trauma that happened. recurrent involuntary and intrusive thoughts about it, nightmares that are repetitive, dissociative reactions like flashbacks, intense or prolonged psychological distress, marked physioloigcal reactivity.
criterion B to diagnose ptsd
criterion b for ptsd is
intrusion sx
avoiding distressing memories/thoughts, avoiding external reminders like people, places, activities, conversations, situations. this criterion for ptsd is
C
criterion c for PTSD is
avoidance
negative alterations in mood that began or worsened after the event plus 2 or more of the following. inability to recall important aspects of the event, constant distorted negative beliefs/expectations about oneself/world, constant distorted cognition leading to self blame, constant negative emotional state, dec interest in activities that were enjoyable before, alienated, can’t be positive. this criterion for ptsd is
D
criterion D for ptsd is
negative alterations in mood
criterion E of ptsd is
alterations in arousal and reactivity
trauma related changes in reactivity and arousal beginning or worsening after event shown by 2 or more of following. irritable or aggressive outbursts, reckless behavior, hypervigilance, exaggerated startle response, can’t focus, can’t sleep. this criterion of ptsd is
E
criterion F of ptsd is
Duration. B, C, D and E sx for more than 1 month.
criterion G of ptsd
disturbance causes functional impairment or distress in social occupational etc. life
criterion h of ptsd
disturbance isn’t bc of substances/meds or another mental illness.
this specification of PTSD is that the full criteria not satisfied until 6 months later from trauma. highest in military members.
delayed expression PTSD
this specification of PTSD is more in childhood or adult sexual assault. higher rates of functional impairment, psych comorbidities and suicidality
dissociative sx PTSD
how to tx PTSD without meds
eye movement desensitization and reprocessing therapy (EMDR) used to process and access unresolved trauma. eye movements can be voluntarily adjusted while thinking about a bad memory to then reduce the anxiety connect ed to it. EMDR is shown to desensitize traumatic memories.
how to tx PTSD with meds
SSRIs like sertraline and paroxetine. if bad sleep then prazosin or clonidine. quetiapine for military vets