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Pathophysiology Exam 3
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What is obesity?
Excess accumulation of body fat that increases health risks
How is obesity diagnosed?
BMI greater than or equal to 30 kg/m squared
What BMI is considered overweight?
BMI 25-29.9 kg/m squared
Besides BMI, what measurement helps assess obesity risk?
Waist circumference
What are the major causes of obesity?
Genetics
Excessive calorie intake
Physical inactivity
Hormonal Disorders
Medications
Environmental/psychological
Which endocrine disorders contribute to obesity?
Hypothyroidism
Cushing syndrome
PCOS
Which medications commonly cause weight gain?
Corticosteroids
Antidepressants
Antipsychotics
Name three diseases associated with obesity?
Type 2 diabetes
Hypertension
Coronary artery disease
Which hormone stimulates hunger?
Ghrelin
Where is gherkin produced?
The stomach
When are ghrelin levels highest?
Before meals`
Which hormone promotes satiety?
Leptin
Where is leptin produced?
Adipose (fat) tissue
Which part of the brain regulates hunger and satiety?
The hypothalamus
What is the function of leptin?
It suppresses appetite and promotes energy expenditure
Which vitamins are fat-soluble?
Vitamins A, D, E, and K
Which vitamins are water-soluble?
Vitamin C and the B-complex vitamins
Which vitamin deficiency causes night blindness?
Vitamin A
Which vitamin deficiency causes rickets?
Vitamin D
Which vitamin deficiency causes osteomalacia?
Vitamin D
Which vitamin deficiency causes scurvy?
Vitamin C
Which vitamin deficiency causes pernicious anemia?
Vitamin B12
Which vitamin deficiency causes neural tube defects?
Folate (Vitamin B9)
Which vitamin deficiency causes Wernicke encephalopathy?
Thiamine (Vitamin B1)
Which vitamin is essential for blood clotting?
Vitamin K
Which fat-soluble vitamin can become toxic and cause hypercalcemia?
Vitamin D
Iron deficiency causes what type of anemia?
Microcytic anemia
Calcium deficiency increases the risk of what disease?
Osteoporosis
Potassium deficiency can cause what cardiac complication?
Cardiac arrhythmias
Sodium excess contributes to what disease?
Hypertension
What characterizes anorexia nervosa?
Restriction of food intake
Intense fear of weight gain
Distorted body image
Common signs of anorexia?
Low BMI
Bradycardia
Hypotension
Amenorrhea
Cold intolerance
Dry skin
Common electrolyte imbalance in anorexia?
Hypokalemia
Why do patients with anorexia feel cold?
Loss of body fat decreases insulation
What defines bulimia nervosa?
Binge eating followed by compensatory behaviors
What are common compensatory behaviors?
Vomiting
Laxative abuse
Fasting
Excessive exercise
What oral finding is common in bulimia?
Dental enamel erosion
Which salivary glands enlarge in bulimia?
Parotid glands
What electrolyte imbalance commonly occurs in bulimia?
Hypokalemia
What distinguishes binge eating disorder from bulimia?
There are no compensatory (purging) behaviors
What medical condition commonly develops from binge eating disorder?
Obesity
What is the purpose of bariatric surgery?
Long-term weight loss and improvement of obesity-related diseases
Name three common bariatric procedures
Sleeve gastrectomy
Roux-en-Y gastric bypass
Adjustable gastric band
Which bariatric surgery is restrictive?
Sleeve gastrectomy
Which bariatric surgery is restrictive and malabsorption?
Roux-en-Y gastric bypass
What is dumping syndrome?
Rapid emptying of stomach contents into the small intestine, causing nausea, cramping, diarrhea, dizziness, and sweating after meals
Which nutrient deficiencies are common after bariatric surgery?
Vitamin B12
Iron
Calcium
Vitamin D
Why are nutrient deficiencies common after Roux-en-Y gastric bypass?
It bypasses portions of the small intestine where nutrients are normally absorbed