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Integumentary System consists of
- Skin
- Hair
- Nails
- Sweat glands
- Sebaceous (oil) glands
What are two major types of skin
- Thick (hairless) skin
- Thin (hairy) skin
Thick (Hairless) Skin
- Covers the palms, planar surfaces of the digits, and planter surfaces (soles) of the feet
Thin (hairy) skin
- Covers most body regions
Major Functions of the Skin
- Prevents entry of toxic substances/patogens
- Reduces water loss
- Regulation of body temperature
- Contains sensory receptors and immune system cells
- Lipid storage
- Vitamin D synthesis (from cholesterol)
- Waste excretion
Skin consists of which two distinct regions
- Epidermis
- Dermis
Epidermis
- Superficial region
- Consists of epithelial tissue (stratified squamous) and is avascular
Dermis
- Underlies epidermis
- Areolar Connective Tissue is superficial to dense irregular Connective Tissue
- Vascular
Subcutaneous layer (Hypodermis)
- Mostly areolar connective tissue (collagenous & elastic fibers are continuous with those in dermis) & adipose tissue
- Anchors skin to underlying tissues and organs but is not technically part of the skin
Epidermis
- Thickness depends on location
What is the thickness of the epidermis on palms
0.8-1.4 mm
What is the thickness of the epidermis on soles
0.07-0.12 mm
What contains four layers (thin skin) or five layers (thick soles)
Epidermis
Hydrophobic Barrier
Secretion of proteins and lipids results in a tough
What does a loss of surface cells stimulate
Mitosis in cells of basal layer
What does Unusual friction/pressure lead to
Calluses/Corns
How many days does it take for cells to move to the surface
25-45 days
What does the Epidermis consists out of
Mostly keratinized stratified squamous epithelium
What are four types of cells found in the the epidermis
- Keratinocytes
- Melanocytes
- Dendritic (Langerhans) cells
- Tactile (Merkel) cells
Keratinocytes
Are the predominat cell type
- Stratified squamous epithelium
- Produce keratin (Protein) fibers
Melanocytes
Are pigment-producing cells
Epidermal dendritic (Langerhans) cells
Are antigen printing cells of immune system
Tactile (Merkel) cells
Are touch receptors at the base of the epidermis (Example: Finger tips)
What do Melanin (Pigment) produce cells within
Stratum basale
What do cellular extensions transfer pigment granules into
Epidermal cells
Skin color differences result from differences in the rate of?
- Melanin secretion NOT number of melanocytes
Melanocytes prevents damage to biological molecules from what being absorbed?
UV light (Exposure to UV-B stimulates melanogenesis)
Thick Skin
Contains five layers (strata) and is found in high-abrasion areas (hands, feet)
Thin Skin
Contains only four strata
Strata
Means Layers
What are the five layers of skin
- Stratum basale
- Stratum spinosum
- Stratum granulosa
- Stratum lucid (Only in thick skin)
- Stratum corneum
Stratum Basale
Deep, single layer of continuously dividing stem cells
Stratum spinous
Cells with weblike pre keratin filaments attached to desmosomes
Stratum Granulosm
- 3 to 5 layers of flattened cells with lamellated granules (secrete lipids) and keratohyalin granules (promote crosslinking of keratin)
Stratum Lucidum
Several rows of flat, dead cells seen only in thick skin
Stratum Corner
20 to 30 layers of dead, flat keratinized cells protect against abrasion, water loss, infection
What is the average thickness of the Dermis
1.0-2.0 mm
What is the dermis of the eyelids
0.5 mm
what is the dermis of the of the feet
3.0 mm
Papillary Layer is what type of tissue
Aerolar Connective Tissue
What does dermal papillae contain?
Capillary loops
What has free nerve endings
Meissner's corpuscles
Reticular Layer
Is dense irregular connective tissue
Collagenous and elastic fibers
Bind dermis to underlying tissues
What are smooth muscle fibers associated with
- Hair Follicles
- Glands
- Skin of scrotum
What do skeletal fibers anchored to dermis provide for
Voluntary movements (Examples: Facial Expressions)
Innervate dermal muscles & glands
Motor Neurons
Innervate sensory receptors (Examples: Touch, temperature, pain receptors)
Sensory Neurons
Hair (Pili)
- Tube-like structures, extend from the surface into the dermis (actually epidermal)
What do specialized epidermal cells form
- Keratinized
- Pigmented
- Dead epidermal cells
What is genetically determined
Pigment deposition by melanocytes
Arrector Pili
- Contracts
- Causes goose bumps (In response to cold, fear)
What does each follicle have and produce
- Oil producing
- (Sebaceous) glands
What does Epithelial cells of nail bed produce?
- Germinal Matrix
- Scale-like cells with lots of keratin
Nail Plate
- (Hard/translucent part of the nail)
- Is layers of keratin
Sweat (Sudorferous) glands
- Widely distributed
- Specialized epithelial cells secrete sweat
(Ex: H2O with salts and wastes including urea and uric acid)
- Merocrine or apocrine secretion
What are the two kinds of sweat glands
- Eccrine
- Apocrine
Eccrine Sweat Glands
- Most numerous/widely distributed
- Respond to high body temperature, emotional stress
Apocrine Sweat Glands; includes, responds, and breaks down what
- Axillary
- Groin
- Aerola regions
- Responds to emotional stress, sexual arousal
- Bacteria breaking down sweat leads to body odor
Ceruminous Glands
Lining of external ear canal; secrete cerumen (earwax)
Cerumen
Earwax
Mammary Glands
Secrete Milk
Sebaceous Glands
- Associated with hair follicles; specialized epithelial cells produce sebum (fatty material)