Lipid Metabolism and Pathophysiology of Atherosclerotic Disease

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Last updated 5:02 AM on 9/12/26
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10 Terms

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lipid levels

- total cholesterol (TC)

- triglycerides (TG)

- LDL-C

- HDL-C

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desirable TC level

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normal TG level

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optimal LDL-C level

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normal HDL-C level (men)

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normal HDL-C level (women)

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main pathways of lipid metabolism

- exogenous

- endogenous

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exogenous pathway

uptake of dietary cholesterol

- dietary fats broken down in the GI tract

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endogenous pathway

hepatic of biosynthesis of cholesterol

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consequences of atherosclerosis

- narrowing of arterial vessels can limit blood flow to tissues = organ damage

- acute plaque rupture can lead to partial or complete vessel occlusion (heart attack, stroke)