Looks like no one added any tags here yet for you.
somatropin MOA
mimics growth hormone
somatropin adverse effects
hyperglycemia, hypothyroidism, hypercalciuria, antibodies to growth hormone, flu like symptoms
somatropin contraindications
children with closed growth plates, patients with tumors, patients with acute illness
somatropin interactions
glucocorticoids
octreotide (Sandostatin) MOA
antagonized effects of growth hormone
octreotide uses
carcinoid tumors, VIPoma (causes severe diarrhea, flushing, and hypotension), esophageal varices
octreotide adverse effects
blood glucose fluctuations, N/V/D, conduction abnormalities, gallbladder impairment
desmopressin (DDAVP) MOA
mimics action of ADH
desmopressin uses
diabetes insipidus (low ADH - polydipsia, polyuria, dehydration), GI bleed, hemophilia and von Willebrand
desmopressin med admin
IV, IM, SUBQ, IN (each spray 10mg, alternate nostrils)
symptoms of hypothyroidism
cold intolerance, weight gain, depression, brittle hair and nails, fatigue
symptoms of hyperthyroidism
diarrhea, flushing, increased appetite, muscle weakness, fatigue, irritability, nervousness, sleep disorders, heat intolerance, altered menstrual flow
thyroid replacement drugs
levothyroxine (Synthroid), desiccated thyroid
patient teaching levothyroxine
take on an empty stomach early in the morning, do not switch products without talking to a provider
thyroid replacement drugs are pregnancy category
A
antithyroid drugs
propylthiouracil (PTU), methimazole
antithyroid drugs adverse effects
liver toxicity, bone marrow toxicity, agranulocytosis, leukopenia, thrombocytopenia, nephritis, enlarged thyroid gland
antithyroid medications are pregnancy class
D (thyroidectomy is best option during pregnancy)
antithyroid patient education
takes 2 weeks for symptom improvement, avoid sources of iodine (iodized salt, tofu, soy, seafood, breads), report s/s of liver and bone marrow toxicity (fever, sore throat, skin eruptions, bleeding/bruising)