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Anatomy
The study of the structures of organisms
Physiology
The study of the functions of the structures of organisms
Homeostasis
The maintenance of the internal environment in a relatively stable state. It is a dynamic process involving continuous internal adjustments to compensate for external changes
Requirements for Individual Animal Cells
Must be surrounded by an aqueous solution for osmotic balance
Tissue
A group of cells with the same structure and function
Organ
A structure that integrates two or more different tissues to carry out a specific function (e.g.
Organ System (Body System)
Coordinates the activities of two or more organs to carry out a major body function such as movement
Factors Determining Tissue Structure and Function
Properties of individual cells
Anchoring Junctions
Cell junctions that form button-like spots or belts
Tight Junctions
Cell junctions that seal spaces between cells
Gap Junctions
Open channels between cells in the same tissue
Four Basic Animal Tissue Types
Epithelial
Epithelial Tissue Function
Protection
Epithelial Tissue Surfaces
Apical surface: The outer surface
Simple Epithelium
Epithelium formed by a single layer of cells.
Stratified Epithelium
Epithelium formed by multiple cell layers.
Squamous Cells
Flattened cell shapes within an epithelium.
Cuboidal Cells
Cube-shaped cell shapes within an epithelium.
Columnar Cells
Elongated cell shapes within an epithelium.
Simple Squamous Epithelium
A layer of flattened cells found in blood vessel walls and air sacs of the lungs. Its function is diffusion.
Stratified Squamous Epithelium
Several layers of flattened cells found in the skin and surfaces subject to abrasion (e.g.
Cuboidal Epithelium
A layer of cube-like cells (which may have microvilli) found in glands and tubular parts of nephrons in kidneys. Its function is secretion and absorption.
Columnar Epithelium
A layer of tall
Epithelial Stem Cells
Undifferentiated cells found in the basal layer of the skin (and in adults in the brain
Exocrine Glands
Glands connected to the epithelium by a duct
Endocrine Glands
Ductless glands that release hormones
Connective Tissue Function
Supports other body tissues
Extracellular Matrix (ECM)
The nonliving material secreted by the cells of connective tissue. Its type and quantity determine the mechanical properties of the connective tissue
Loose Connective Tissue
Consists of sparsely distributed fibroblast cells surrounded by an open network of collagen and other glycoprotein fibers. It supports epithelia
Dense Connective Tissue
Has sparsely distributed fibroblasts among dense masses of collagen and elastin fibers arranged in highly ordered
Cartilage
Consists of sparsely distributed chondrocytes surrounded by networks of collagen fibers embedded in a tough
Bone
Forms the skeleton
Osteon
The structural unit of bone
Adipose Tissue
Contains large
Blood
The major transport vehicle of the body
Erythrocytes
Red blood cells
Leukocytes
White blood cells
Platelets
Membrane-bound fragments of specialized blood cells that participate in blood clotting.
Muscle Tissue
Consists of cells with the ability to contract (shorten) due to the interaction of actin and myosin proteins. It moves body limbs
Skeletal Muscle
Attached by tendons to the skeleton
Cardiac Muscle
Striated muscle that contracts spontaneously (involuntarily). Its cells are short and branched
Smooth Muscle
Found in the walls of tubes and cavities (e.g.
Nervous Tissue
Contains nerve cells (neurons) that serve as lines of communication and control
Neuron
A nerve cell consisting of a cell body
Extracellular Fluid (ECF)
The fluid that supplies nutrients and oxygen to cells and eliminates wastes in multicellular organisms. It has two components: plasma (fluid portion of blood) and interstitial fluid (fluid surrounding cells).
Regulator (Homeostatic Control)
An animal that maintains factors of its internal environment in a relatively constant state (e.g.
Conformer (Homeostatic Control)
An animal whose internal environment matches the external environment (e.g.
Negative Feedback Control
A homeostatic mechanism that cancels the system responsible for the initial response
Positive Feedback Mechanism
A mechanism that intensifies or adds to a change in the internal or external environment. These are not as common as negative feedback because they do not result in homeostasis (e.g.
Acclimatization
A temporary change in a physiological process that occurs during the life of an animal in response to natural alterations in environmental conditions.
Acclimation
A change in a set point that occurs artificially in a laboratory setting.
The Endocrine System
Hormone
A regulatory chemical secreted into extracellular fluid and carried by the blood. It can act at a distance from its source and must be complex enough to convey regulatory information and stable enough to resist destruction.
Neurohormone
A regulatory chemical released from neurons that travels in the blood
Paracrine Regulators
Signaling molecules that do not travel in the blood
they allow cells of an organ to regulate each other.
Autocrine Regulators
Signaling molecules secreted by the same cell that has the receptor target.
Pheromones
Chemicals released into the environment to communicate among individuals of a single species
Four Classes of Hormones
Amine
Amine Hormones
Involved in classical endocrine and neuroendocrine signaling. Most are hydrophilic (bind to cell surface receptors) and based on tyrosine
Peptide Hormones
Involved in classical endocrine and neuroendocrine signaling. They consist of amino acid chains
Steroid Hormones
Involved in classical endocrine signaling. They are hydrophobic molecules derived from cholesterol
Fatty Acid-Derived Hormones
Involved in paracrine and autocrine regulation. They are important local regulators secreted by most cells
Lipophilic (Nonpolar) Hormones
Fat-soluble hormones (steroid and thyroid hormones) that travel on transport proteins in blood and bind to intracellular receptors
Hydrophilic (Polar) Hormones
Water-soluble hormones (all others besides steroid and thyroid) that are freely soluble in blood and bind to extracellular receptors
Amplification (Hormone Signaling)
A process in which small quantities of hormones can produce profound effects because each activated protein activates a larger number of proteins for the next step in the pathway.
Endocrine vs. Exocrine
Endocrine: Product secreted into extracellular fluid and carried in blood. Exocrine: Secrete product into a duct.
Pituitary Gland (Hypophysis)
Hangs by a stalk from the hypothalamus and consists of two parts: the anterior pituitary (adenohypophysis) and the posterior pituitary (neurohypophysis).
Anterior Pituitary Hormones (Examples)
Thyroid Stimulating Hormone (TSH)
Tropic Hormones (Tropins)
Hormones that act on other endocrine glands. Examples include TSH
Growth Hormone (GH)
A non-tropic hormone from the anterior pituitary that stimulates cell division
Prolactin (PRL)
A non-tropic hormone from the anterior pituitary that stimulates the development of secretory cells of mammary glands and milk synthesis post-partum.
Posterior Pituitary Hormones
Anti-diuretic Hormone (ADH) and Oxytocin.
Anti-diuretic Hormone (ADH)
Stimulates kidney cells to absorb more water from urine
Oxytocin
Stimulates the ejection of milk from the mammary glands of a nursing mother
it is also present in males.
Thyroid Gland Hormones
Thyroxine (T4
Calcitonin
A peptide hormone secreted by the thyroid gland that stimulates the uptake of calcium (Ca2+) into bones
Parathyroid Hormone (PTH)
Produced by the parathyroid glands
Adrenal Medulla Hormones
Epinephrine and Norepinephrine (catecholamines)
Adrenal Cortex Hormones
Corticosteroids
Pancreatic Islets of Langerhans Hormones
Insulin (from beta cells) and Glucagon (from alpha cells)
Insulin Function
Secreted by beta cells
Glucagon Function
Secreted by alpha cells
Diabetes Mellitus Type I
Insulin-dependent diabetes
Diabetes Mellitus Type II
Noninsulin-dependent diabetes
Melatonin
A hormone secreted by the pineal gland that synchronizes various body processes to a circadian rhythm
Sex Steroids (from Gonads)
Estrogen and Progesterone ("female" hormones) and Androgens (e.g.
Ecdysone
A steroid hormone secreted by prothoracic glands in insects
Juvenile Hormone (JH)
A terpenoid secreted by the corpora allata in insects. High levels produce a larger larva during a molt
Molt-Inhibiting Hormone (MIH)
A peptide neurohormone secreted by a gland in the eye stalks of crustaceans. It inhibits ecdysone secretion when the body size is too small for a molt.
Animal Reproduction
Asexual Reproduction
A single individual gives rise to genetically identical offspring without genetic input from another individual. Advantages include preserving genetic uniformity and no energy expenditure for gametes or mate finding.
Fission (Asexual)
A mitotic mechanism where the parent separates into two or more offspring of approximately equal size (e.g.
Budding (Asexual)
A mitotic mechanism where a new individual develops while attached to the parent
Fragmentation (Asexual)
A mitotic mechanism where pieces separate from the parent's body and develop (regenerate) into new individuals (e.g.
Parthenogenesis
A form of asexual reproduction where animals produce offspring by the development of an egg without fertilization. Offspring are not genetically identical to the parent or each other because the egg is produced by meiosis.
Sexual Reproduction
Male and female parents produce offspring through the fusion of gametes (egg and sperm) generated by meiosis. Advantages include generating genetic diversity among offspring.
Gametogenesis
The cellular mechanism of sexual reproduction involving the formation of male and female gametes from germ cells located in specialized organs called gonads.
Fertilization
The union of haploid sperm and egg during sexual reproduction
Spermatogenesis
The process in males that produces four mature
Sperm Structure
Typically motile cells with a flagellum