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Sexual identity
Biological sexual characteristics
Gender Identity
Conviction of being male or female
Sexual orientation
Describes the object of a person’s sexual impulses
Criteria for Gender Dysphoria (Children)
A. Marked incongruence between one’s experience/expressed gender and assigned gender; at least 6 months duration with at least 6 of the following:
Strong desire to be other gender or insistence that one is other gender
[In those assigned male at birth]- strong preference for cross-dressing or simulating female attire; [In those assigned female at birth]- strong preference for wearing only typically masculine clothing and strong resistance to feminine clothing
Strong preference fro cross-gender roles in fantasy play
Strong preference for the toys/games/activities stereotypically used in other gender
Strong preference for playmates of other gender
In boys- strong rejection of typically masculine toys/games/activities with avoidance of ‘rough-and-tumble’ play; In girls- strong rejection of typically feminine play
Strong dislike of one’s sexual anatomy
Strong desire for the primary/secondary characteristics that match one’s ‘experienced’ gender
B. clinically significant distress or impairment
What duration is needed dx gender dysphoria
6 months
Criteria for Gender Dysphoria (Adolescence / Adult)
A. Marked incongruence between one’s experienced/expressed gender and assigned gender, at least 6 months with at least 2 of the following:
Marked incongruence between one’s experienced/expressed gender and primary/secondary sex characteristics
Strong desire to be rid of one’s primary/secondary sex characteristics because of marked incongruence with one’s experience/expressed gender
Strong desire for primary/secondary sex characteristics of the other gender
Strong desire to be of the other gender
Strong desire to be treated as the other gender
Strong conviction that one has the typical feelings and reactions of the other gender
B. clinically significant distress or impairment
What is the normal gender development in children
2-3 years old: can recognize gender differences
3-5 years old: Will start to play with “gender appropriate toys”
5-6 years old: Will start to spend most of the time playing with children of the same sex
Treatment for Gender Disorders
Individualized approach
Screen for concerns of underlying depression, anxiety, eating disorders, sexual abuse/trauma and treat appropriately
Psychotherapy for patient and family members
Some patients will choose socially transitioning to opposite sex
Some patients will choose medical or surgical interventions
Sexual Disorders
Person’s inability to participate in a sexual relationship that he or she would wish
What needs to be rule out before dx of sexual disorders
an acquired medical condition
use of pharmacological substance that could account for or contribute to the dysfunction
How long must a sexual disorder present to be dx
6 months
Types of Female Sexual Disorder
Genito-Pelvic pain disorder
Female orgasmic disorder
Female sexual interest/arousal disorder
Types of Male Sexual Disorder
Male hypoactive sexual desire disorder
Erectile disorder
Premature ejaculation
Delayed ejaculation
Criteria for Genito-Pelvic Pain Disorder
A. Persistent or recurrent difficulty with one of the following
Vaginal penetration during intercourse
Marked vulvovaginal or pelvic pain during intercourse or penetration attempts
Marked fear/anxiety about vulvovaginal or pelvic pain in anticipation of, during or as a result of vaginal penetration
Marked tightening or tensing of pelvic floor muscled during attempted penetration
B. persisted for at least six months
C. clinically significant distress
D. not better explained by a nonsexual mental disorder or as a consequence of severe relationship distress or other significant stressors, and it is not attributable to substance/medication/medical issue
What are the clinical features of genito-pelvic pain
May not be able to insert anything into the vagina
Dyspareunia
Vagismus
May avoid sexual situations out of fear
Relationship strain
Not related to an organic problem or decreased lubrication
Can worsen during post-partum period
Dyspareunia-
recurrent genital pain occurring before, during, or after intercourse
Vagismus-
constriction of the outer third of the vagina due to involuntary pelvic floor muscle tightening
Risk Factors for Genito-Pelvic Pain Disorder
History of sexual and/or physical abuse
Anxiety or guilt about sexual act
Frequently occurring with other mentioned sexual dysfunctions
Treatment for Genito-Pelvic Pain Disorder
Sex therapy
Couples therapy
Individual psychotherapy
Pelvic floor PT
Sex therapy
teach about normal sexual function and cycles, discuss concerns about sexual activity, and offer suggestions and exercises to improve sexual relationships between couples
Criteria for Female Orgasmic Disorder
A. either of the following symptoms and experienced on almost all or all occasions of sexual activity
Marked delay in, marked infrequency of, or absence of orgasm
Markedly reduced intensity of orgasmic sensations
B. have persisted for at least six months
C. clinically significant distress
D. not better explained by a nonsexual mental disorder or as a consequence of severe relationship distress or other significant stressors, and it is not attributable to substance/medication/medical issue
What are the clinical features female orgasmic disorder
Women generally complain more or are more concerned with poor interest/desire/arousal
Cannot achieve orgasm with clitoral manipulation
May still feel satisfied
What is often needed to achieve orgasm in women
Most women need clitoral manipulation during intercourse
Minority of women can have an orgasm with intercourse alone
Primary Female Orgasmic Disorder
never experienced orgasm
Secondary Female Orgasmic Disorder
previously experienced orgasm or can only experience orgasm through masturbation
How does female orgasmic disorder change with age
Many women are able to have more orgasms as they get older
Risk Factors for Female Orgasmic Disorder
Anxiety
Sociocultural factors like gender role expectations
Treatment for Female Orgasmic Disorder
Sex Therapy
Couples Therapy
Psychotherapy
Devices in increase clitoris blood flow (Vibrators / EROS-CTD)
Criteria for Female Hypoactive Sexual Desire Disorder-
A. Lack of, or significantly reduced, sexual interest/arousal, as manifested by at least three of the following:
Absent/reduced interest in sexual activity
Absent/reduced sexual/erotic thoughts or fantasies
No/reduced initiation of sexual activity / unreceptive to a partner’s attempts to initiate
Absent/reduced sexual excitement/pleasure during sexual activity in almost all or all sexual encounters
Absent/reduced sexual interest/arousal in response to any internal or external sexual/erotic cues
Absent/reduced genital or nongenital sensations during sexual activity in almost all or all sexual encounters
B. Duration for 6 months
C. significant distress
D. not better explained by a nonsexual mental disorder or as a consequence of severe relationship distress or other significant stressors, and it is not attributable to substance/medication/medical issue
What are the clincial features of Female Hypoactive Sexual Desire Disorder
Decreased or lack of sexual feelings, thoughts, desires
Infrequent sexual activity
Difficulty experiencing orgasm
Pain during intercourse
Subjective and objective evidence of arousal may not correlate
What factors should be considered for Female Hypoactive Sexual Desire Disorder
1. Partner factors: partner sexual issues, health
2. Relationship factors: poor communication, discrepancies in desire
3. Individual vulnerability factors, psych issues or stressors: body image, h/o abuse, recent job loss, bereavement
4. Cultural factors
5. Medical factors: general health, aging, medications, menopause
Risk Factors for Female Hypoactive Sexual Desire Disorder
Negative cognitions or attitudes about sexuality
History of mental disorder
History of medical conditions: DM, thyroid dysfunction
Treatment for Female Hypoactive Sexual Desire Disorder
Lifestyle changes
Sex therapy/couples therapy/individual psychotherapy
Medications:
What medications can be given for Female Hypoactive Sexual Desire Disorder
Flibanserin (Addyi)
Bremelanotide (Vylessi)
Buproprion (Wellbutrin) off label
Flibanserin (Addyi)
Selective Serotonin antagonist
Indication for Flibanserin (Addyi)
Female Hypoactive Sexual Desire Disorder in premenopausal women
SE for Flibanserin (Addyi)
hypotension
lightheadedness
syncope
What can increase the side effects of Flibanserin (Addyi)
•alcohol within 2 hours of taking medication
Bremelanotide (Vylessi)
SQ Melanocortin receptor agonist
What is the difference between taking Flibanserin (Addyi) and Bremelanotide (Vylessi)
Flibanserin → PO daily
Bremelanotide → SQ 45 min prior to sexual activity
SE of Bremelanotide (Vylessi)
N/V
Flushing
Headache
HTN
Criteria for Male Hypoactive Sexual Desire Disorder
A. Persistently or recurrently deficient or absent sexual/erotic thoughts or fantasies AND desire for sexual activity
B. persisted for at least 6 months
C. clinically significant distress
D. not better explained by a nonsexual mental disorder or as a consequence of severe relationship distress or other significant stressors and is not attributable to another substance/medication/medical condition
What are the clinical features of Male Hypoactive Sexual Desire Disorder
Lack of interest in sexual activity or sexual thoughts/fantasies
Should be a source of distress for patient
Risk Factors for Male Hypoactive Sexual Desire Disorder
ETOH
Psychiatric conditions (especially depression and anxiety)
Relationship issues
erectile/ejaculation issues
Treatment for Male Hypoactive Sexual Desire Disorder
Sex therapy/couples therapy/individual psychotherapy
Criteria for Erectile Disorder
A. one of the three following symptoms on almost all or all occasions of sexual activity
Marked difficulty in obtaining an erection during sexual activity
Marked difficulty in maintaining an erection until the completion of sexual activity
Marked decrease in erectile rigidity
B. persisted for at least six months
C. clinically significant distress
D. not better explained by a nonsexual mental disorder or as a consequence of severe relationship distress or other significant stressors and is not attributable to another substance/medication/medical condition
What are the clincial features of Erectile Disorder
Low self esteem/confidence
Decreased sense of masculinity
Fear/avoidance of sexual encounter
How does age effect male erection
Longer refractory period
More direct stimulation needed
Penile rigidity decreases
Longer time to erection
What should be rule out in erectile disorder
Diabetes
Vascular Disease
Pelvic Surgeries / XRT
Medication (Antidepressant / Antipsychotics / Antihypertensive )
What are red flags for erectile disorder > organic cause
Spontaneous erections when not planning on having intercourse?
Morning erections?
Erections during masturbation or partners other than his usual one?
Treatment of Erectile Disorder
Limit stress
Masturbation – increase confidence in abilities
Good sleep, exercise, balanced diet etc.
Individual psychotherapy/couples therpay/sex therapy
Vacuum pumps
Phosphodiesterase-5 (PDE-5) inhibitors
SE of Phosphodiesterase-5 (PDE-5) inhibitors
Hypotension
What medications cannot be taken with Phosphodiesterase-5 (PDE-5) inhibitors
alpha blockers
nitrates
Sildenafil (Viagra
(PDE-5) inhibitors
vardenafil (Levitra),
(PDE-5) inhibitors
tadalafil (Cialis)
(PDE-5) inhibitors
Criteria of Premature Ejaculation
A. persistent or recurrent pattern of ejaculation occurring during partnered sexual activity within one minute following vaginal penetration and before the individual wishes it
B. persisted for at least six months
C. clinically significant distress
D. not better explained by a nonsexual mental disorder or as a consequence of severe relationship distress or other significant stressors and is not attributable to another substance/medication/medical condition
How does premature ejaculation differ from DSM-5 and Urology
DSM-5 → Within one min
Urology → Within two min
What are the clinical features of Premature Ejaculation
Not the same as when a patient or their female partner is concerned because ejaculation occurs prior to female orgasm
Many report feeling a sense of no control over ejaculation
Causes a lot of apprehension, embarrassment about future sexual contact
Most Common Male Sexual Dysfunction
Premature Ejaculation
Risk Factors for Premature Ejaculation
Hyperthyroidism
prostatitis
anxiety disorder– especially social phobia
Treatment for Premature Ejaculation
Psychotherapy
Pharmacotherapy
SSRI’s
Topical anesthetics
When are topical anesthesia applied for premature ejaculation
5 min prior
Criteria for Delayed Ejaculation Disorder
A. Either of the following symptoms must be experienced on almost all or all occasions of partnered sexual activity and without the individual desiring delay
1. Marked delay in ejaculation
2. Marked infrequency or absence of ejaculation
B. persisted for at least six months
C. clinically significant distress
D. not better explained by a nonsexual mental disorder or as a consequence of severe relationship distress or other significant stressors and is not attributable to another substance/medication/medical condition
What are the clinical features of Delayed Ejaculation
Repeated thrusting that results in stopping the activity due to either frustration, exhaustion or partner pain
Rarely present with masturbation
Risk Factors for Delayed Ejaculation
Age Realted (esp > 50)
What factors should be considered for delayed ejaculation
1. Partner factors: partner sexual issues, health
2. Relationship factors: poor communication, discrepancies in desire
3. Individual vulnerability factors, psych issues or stressors: body image, h/o abuse, recent job loss, bereavement
4. Cultural factors
5. Medical factors
Treatmetn for Delayed Ejcaulation
Sex therapy/couples therapy/individual psychotherapy
Paraphilias
Sexual excitement only by unusual or bizarre stimuli
Paraphilic disorder:
paraphilia that causes distress or impairment or involves harm to others
Treatment for Paraphilias
Treat common comorbid conditions
specific behavior modification techniques
May see SSRI/SNRI or Depo-Provera used in treatment of hypersexual states
most common paraphilia
Pedophilia
Pedophilia
Engaging in sexual activity with children of the opposite or same sex
Children must be less than 13 years old; offender must be at least 16 years old and 5 years older than the victim
Voyeruism (aka Scopophila)
Recurrent preoccupation with fantasies and acts that involve observing people who are naked or engaged in grooming or sexual activity
Masturbation usually accompanies or follows the event
Exhibitionism
Exposing genitals to unsuspecting people in a manner that shocks them
Sexual excitement occurs in anticipation of the exposure and orgasm is brought by masturbation during or after the event
Fetishism
Sexual focus is on objects that are intimately associated with the human body
Sexual preference for inanimate objects
Transvestic Fetishism
Source of sexual gratification obtained from wearing women’s clothing, particularly lingerie, as an adjunct to masturbation or coitus
Frotteurism
Sexual gratification is obtained from rubbing the penis against a nonconsenting, unaware woman
Sexual Masochism
recurrent preoccupation with sexual urges involving the act of being humiliated, beaten, bound, or made to suffer
Sexual Sadism
derive pleasure from expressing their aggressive instincts
What races have the highest rates of suicide in the US
American Indian / Alaska Native (#1)
White (#2)
Native Hawaiian / Pacific Islander (#3)
What is the gender difference in suicide
Women are more likely to attempt
Men are more likely to die
Most Common Methods of Suicide in US Adults
Firearm (#1)
Suffociation (Most for children)
Poisoning
What age ranges are most common in suicide
85+ (#1)
75-84 (#2)
35-44 (#3)
Deliberate self-harm/ Parasuicide/ Self-injurious behavior (SIB)
Willful self-inflicting of painful, destructive, or injurious acts without intent to die.
Types of Suicidal ideation
Passive
Active
Passive Suicidal ideation
Wish to be dead
Active Suicidal ideation
Thought of serving as the agent of one’s own death
Suicide attempt
Self-injurious behavior with a nonfatal outcome accompanied by explicit or implicit evidence that the person intended to die
Aborted suicide attempt
Potentially self-injurious behavior with explicit or implicitly evidence that the person intended to die but stopped the attempt before physical damage
Suicide
Self-inflicted death with explicit or implicit evidence that the person intended to die.
Risk Factors for Suicide
History of suicide attempt (#1)
Psychiatric disorders
Substance use
Medications
Age, sex, race
Marital status
Occupation
Military service
Adverse childhood experiences
Family history
Medical illness
What medications have been linked to suicidial behavior
Antidepressants
Glucocorticoids
Anticonvulsants
Tramadol (Ultram)
Varenicline (Chantix)
Isotretinoin (Accutane)
Montelukast (Singulair)
What anticonvuslants are linked to sucidiality
Gabapentin
Lamotrigine
Oxcarbazepine
Tiagabien
what professions are considered high risk for suicide
First responders (police, fire, EMS)
Military
Doctors/dentists
What are protective factors for suicide
Social support and family connectedness
Pregnancy and parenthood
Religiosity and participating in religious activities
What are myths about suicide
Asking about suicide will put the thought into their head
If someone is suicidal, they will do it no matter what you do.
If someone is going to do it, they are not going to tell you
If you stop someone from killing themselves, they will just find another way.
Columbia Suicide Severity Rating Scale (CSSRS)
An assessment tool that can be universally used to evaluate a patient for suicidal ideation and behavior
Nine Item (PHQ-9)
A depression scale that can indicate sucidiality
Beck Hopelessness Scale
20-item true/false questionnaire that correlates more closely with current suicide attempt than depression severity