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Identify the functions of the upper airway.
As as a filter, humidify, to prevent foreign materials from entering the tracheobronchial tree
Identify what types of epithelium line the anterior one-third of the nasal cavity.
stratified squamous epithelium
Identify what types of epithelium line the posterior two-thirds of the nasal cavity.
Pseudostratified columnar epithelium
Describe where the vallecula is located.
between the glossoepiglottic folds on each side of the posterior oropharynx (from the base of the tongue to the epiglottis)
Identify the functions of the larynx.
-A passageway of air between the pharynx and the trachea
-Generates sound for speech
-Serves as a protective mechanism against aspiration of solids and liquids.
Identify what structures are included in the cartilaginous airways
trachea, main stem bronchi, lobar bronchi, segmental bronchi, sub segmental bronchi (conducting zone)
Identify what structures are included in the noncartilaginous airways
Bronchioles and terminal bronchioles (conducting zone)
Identify what structures are included in the the site of gas exchange
-respiratory bronchi
-alveolar ducts and sacs (respiratory zone)
Identify risk factors that cause the rate of mucociliary transport to decrease.
cigarette smoke
dehydration
positive pressure
ventilation
excessive bronchial secretions
hypoxia
air pollution
Describe where the carina is located
the bifurcation (division) of the trachea
Describe the effects the sympathetic nervous system has on the bronchial smooth muscle.
stimulates beta 2 receptors in the bronchial smooth muscles causing relaxation (bronchodilation)
Explain how far the base of the lungs extend in relationship to the thoracic cage.
base of lungs extend anteriorly to about the level of the 6th rib (xiphoid process) and posteriorly to the level of the 11th rib (2 ribs below the inferior angle of the scapula)
Identify the nerves that stimulate the diaphragm.
Phrenic nerves
Explain when gas flow stops in the lungs when comparing a normal inspiration to expiration.
the pressure inside the alveoli and outside the atmosphere are equal at the end of inspiration (when gas flow stops)
Explain how the bronchial airways respond during a normal inhalation
beginning of inspiration pressure is the highest in the atmosphere; lower pressure in the alveoli
End of inspiration: state of equilibrium
Explain how the bronchial airways respond during a normal exhalation
beginning of exhalation the pressure is the highest in the alveoli; lower pressure is in the atmosphere.
At the end of expiration: State of equilibrium
Define driving pressure.
the pressure difference between 2 points in a tube/vessel.
Describe the difference between transrespiratory (transairway) pressure
pressure difference between barometric pressure and alveolar pressure.
Describe the difference between transmural pressure
pressure difference that occurs across the airway subtracting the intra airway pressure form the pressure on the outside of the airway
describe the difference between transpulmonary pressure
pressure difference between alveolar pressure and pleural pressure
describe the difference between transthoracic pressure
pressure difference between alveolar pressure and body surface pressure
Describe the elastic properties of the lung and chest wall.
Chest wall has a natural tendency to move outward or expand. Lungs have a natural tendency to move inward and collapse.
Identify what type of cells produce pulmonary surfactant
alveolar type II cells
Identify what forces cause the lung to recoil.
elastic properties and surface tension
Describe Poiseuille's Law
Inspiration: bronchial airways (lengthen and increase in diameter)
Expiration: bronchial airways (decrease in diameter and lengthen in diameter)
Describe the effects of airway resistance on ventilatory patterns.
increases the pt. RR decreases and the tidal volume increases
Describe the effects of airway lung compliance on ventilatory patterns
the pt. RR increase while at the same time, the tidal volume decreases
If lung compliance decrease
the tidal volume decrease
decrease lung compliance is known as
stiff lungs
What conditions are associated with decreased lung compliance?
pulmonary fibrosis
atelectasis
frail chest
pulmonary edema
pneumonia
What happens to the RR with decreased lung compliance?
RR goes up; patient breathe fast
What happens to the tidal volume when the lungs are stiff?
goes down
If RAW decreases
RR will increase; Inflation time decrease
Identify the 3 components of the ventilatory patterns.
Tidal volume (volume of air in mL that we breathe in and out)
Ventilatory Rate (RR)
Time relationship (I:E Ratio)
Calculate minute alveolar ventilation
[tidal volume-dead space] x RR
-Answer is mL/min
Define deadspace
volume of inspired air that does not reach the alveoli and is not effective (does not participate in gas exchange)
Dalton's Law
the law of partial pressure
How to measure barometric pressure
with a barometer
Fick's Law
the rate of gas transfer across a sheet of tissues.
proportional to the surface area of the tissue, the diffusion of constant (quantity of the substance), and the difference in the partial pressure
Inversely proportional to the thickness of the tissue
Conditions that effect the rate of gas transfer at the ac membrane?
thickness of the lungs
surface area
quantity of the diffusion of gasses
difference in the partial pressure
Henry law
amount of gas that dissolves in a liquid at a given temp is proportional to partial pressure of a gas
graham law
rate of diffusion of gas through liquid.
is directly proportionate to the solubility coefficient
is inversely proportionate to the weight
Identify the normal barometric pressure at sea level.
760 mmHg or torr
Identify the gases that compose the barometric pressure and their percentages.
Nitrogen= 78%
Oxygen= 21%
Carbon dioxide= 0.2%
other= 0.93%
Identify what the normal partial pressure of water (PH2O) is at 37 ̊C.
47.0 mmHg
Identify what the abbreviation PAO2 stand for?
Alveolar partial pressure of O2 in the blood
Identify what the abbreviation PaO2 stand for
Arterial partial pressure of O2 in the blood
How do you get the PaO2
ABG (arterial blood gas)
Identify what normal absolute humidity is in an alveolar gas.
44 mg/L
Calculate the alveolar air equation (PAO2)
PAO2= [PB-PH2O x FIO2]-PaCO2 (1.25)
Explain how long it usually takes blood to move through the AC membrane at rest.
0.75 seconds
Identify the gases that exhibit perfusion limited
nitrous oxide
Identify the gases that exhibit diffusion limited
carbon monoxide
Can be diffusion and perfusion limited but, it is normally perfusion limited.
oxygen
Identify what conditions affect the rate of gas diffusion
Atelectasis (alveolar collapse)
Alveolar fibrosis (thickening of alveoli wall)
pneumonia (consolidation)
pulmonary edema
secretions
interstitial edema (interstitial space is swollen)
emphysema
Identify the normal range for leukocytes
4,000-12,000 cells/mm3
Identify the normal range for platelets.
150,000-400,000 cells/mm3
Identify what leukocytes are considered to be granulocytes
Neutrophils
Eosinophils
Basophils
Identify what leukocytes are considered to be agranulocytes
lymphocytes
monocytes
thrombocytes (platelets)
Identify the normal percentage of eosinophils in the blood.
2-5% in the blood
When are eosinophils increased?
in pt. with asthma
Identify how many chambers are in the heart.
4 chambers
Identify the structure that separates the right and left ventricles.
interventricular septum
Identify the structure that separates the left and right atrium.
interatrial septum
myocardium
middle layer (thickest layer)
Endocardium
connective tissue layer (inside)
Pericardium (epicardium)
outer visceral layer (squamous epithelium cells)
Describe where the vasomotor center is located.
medulla oblongata
Describe where baroreceptors are located
in the walls of the carotid arteries and the aorta arch
Identify the layers of arteries
tunica intima (inner layer)
tunica media (middle layer)
tunica adventitia (outer layer)
What can cause symptoms of increased RAW?
secretion, mucus, tumors, body aspirations. Blocks airway. Increase CL (lung compliance).
What pt have increased lung compliance (CL) ?
COPD (emphysema) due to air trapping
Increased RAW causes pt lungs to take more time to do what?
inflate