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cell signaling
The molecular mechanisms that enable cells to respond to their environment are collectively
signaling pathway
Signaling molecules act on target cells by triggering a series of interactions between molecules
Reception
signaling molecule binds to a receptor protein by fitting into an appropriately shaped binding site
A molecule that binds to a receptor in this way is a
ligand
All of the interactions between molecules that are triggered by activation of a receptor, and lead to a cell’s response
signal transduction
enzymes that transfer a phosphate group from ATP to one or more specific amino acids on
target proteins
protein kinases
target proteins subtly changes their conformation. This change can activate or inactivate a target protein, depending on the particular protein and where it is phosphorylated.
Phosphorylation
Protein kinases often phosphorylate other protein kinases, producing a
phosphorylation cascade
The purpose of reception and transduction is to change the functioning of a target cell.
Response
cells recognize each other using direct contact communication, and cellular responses in these signaling pathways reinforce the attachments between cells.
cell–cell recognition
In animal cells, the direct channels of communication are ___ , specialized connections between the cytoplasms of adjacent cells
gap junctions,
In plant cells, the direct channels of communication are
plasmodesmata
aqueous fluid surrounding and between the cells.
extracellular fluid
A specialized type of paracrine signaling in animals takes place at
chemical synapses
molecules that diffuse across the chemical synapse and bind to receptors in the plasma membrane of the adjacent cell.
neurotransmitters
In some cases, the local regulator acts on the same cell that produces it, a process called
autocrine regulation
form of communication, one cell secretes a long-distance signaling molecule called; which produces a response in target cells that may be far from the hormone-secreting cell
hormone
(hormaein= to excite)