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biochem exam #1
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Alanine
Ala, A, Nonpolar Aliphatic R Group

Glycine
Gly, G, Nonpolar Aliphatic R Group

Isoleucine
Ile, I, Nonpolar Aliphatic R Group

Leucine
Leu, L, Nonpolar Aliphatic R Group

Proline
Pro, P, Nonpolar Aliphatic R Group

Valine
Val, V, Nonpolar Aliphatic R Group

Phenylalanine
Phe, F, Aromatic R Group, non polar

Tryptophan
Trp, W, Aromatic R Group, non polar (but the N-H can form weak H bonds sometimes, because indole structure outweighs small poolarity)

Tyrosine
Tyr, Y, pKa=10, Aromatic R group, polar (bc of OH) BUT uncharged

Aspartic acid (at low pH)/ Aspartate (at pH=7.4)
Asp, D, pKa= 3.7, Aspartate → deprotonated, Negatively Charged R Group, opposite for Aspartic acid (neutral at pH < 4)

Glutamic acid (at low pH)/ Glutamate (at pH=7.4)
Glu, E, pKa= 4.3, Glutamate→ deprotonated, Negatively Charged R Group, opposite for Glutamic acid (neutral at low pH, protonated)

Arginine
Arg, R, pKa= 12, Positively Charged R Group

Histidine
His, H, pKa= 6, Positively Charged R Group, SPECIAL (ionizes at pH=7.4 bc pKa=6) so half protonated species, half deprotonated (neutral) species

Lysine
Lys, K, pKa= 10, Positively Charged R Group

Serine
Ser, S, pKa= 13, Uncharged Polar R Group

Threonine
Thr, T, pKa= 13, Uncharged Polar R Group

Cysteine
Cys, C, pKa= 8, Uncharged Polar R Group, can form disulfide bonds in oxidative environments

Methionine
Met, M, Nonpolar Aliphatic R Group

Asparagine
Asn, N, Uncharged Polar R Group

Glutamine
Gln, Q, Uncharged Polar R Group
