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Integumentary - hair, skin, nails & glands
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integumentary system functions include
protection
sweat excretion
sensory
thermoregulation
vitamin D synthesis
integument
aka the skin, body’s largest organ
integument’s 2 layers are:
epidermis and dermis
cutaneous membrane made of keratinized stratified squamous epithelium, located on top of the dermis, avascular, made of 4-5 layers
epidermis
how many layers does thin skin have?
4 layers
how many layers does thick skin have?
5 layers
what part of the body contain “thick skin”
palms of hands & soles of the feet
what are the epidermis layers
stratum corneum (most superficial)
stratum lucidum
stratum granulosum
stratum spinosum
stratum basale (deepest)
which epidermis layer is NOT composed of keratinocytes (cells that produce keratin)?
stratum corneum
stratum lucidum
stratum granulosum
stratum spinosum
stratum basale
stratum basale
made up of areolar and dense irregular connective tissues
dermis
underneath the skin (deep to the dermis), well vascularized and composed of loose areolar & adipose tissue, NOT part of the skin
hypodermis
undergo mitosis to produce keratinocytes
basal cells
receptors responsible for stimulating sensory nerve that the brain perceives as touch
merkel cells
melanin production, pigment responsible for color of the hair & skin
melanocytes
small, finger-like projections of the dermis that extend upward into the epidermis, increasing the surface area between the skin layers
dermal papillae
"glue-like connections" between neighboring cells; hold cells tightly together so they don't pull apart when the tissue is stretched, scraped, or rubbed
desmosomes
a clear protein rich in lipids, derived from keratohyalin, giving keratinocytes their transparent appearance
eleiden
immune cells, help fight infections
langerhans cell
tiny, oil producing glands are called
sebaceous glands
two layers of the dermis
papillary layer and reticular layer
papillary layer
composed of loose areolar connective tissue
reticular layer
can see lots of fibers, composed of dense irregular connective tissue (NOT made by reticular fibers and NOT reticular connective tissue !!!)
hypodermis functions include
insulation, fat storage, & cushioning
functions of the hair
protection (from sunburn, injury, bugs)
heat retention
sensory reception
visual identification
chemical signal dispersal
Which layer of the epidermis is deepest, attached to the dermis, and characterized by actively mitotic stem cells responsible for continually replenishing the upper epidermal layers?
stratum corneum
stratum basale
stratum spinosum
stratum lucidum
stratum basale
What is the primary characteristic and functional importance of the outermost layer of the epidermis, the stratum corneum?
a. it contains actively dividing melanocytes that determine baseline skin tone
b. it is rich in blood vessels that nourish the deeper layers of the epidermis
c. it consists of dead keratinized cells that form a durable, water-resistant protective barrier
d. its the thickest layer of the dermis containing dense collagen bundles
c. it consists of dead keratinized cells that form a durable, water-resistant protective barrier
.
As keratinocytes migrate from the stratum basale toward the skin surface, they accumulate a tough, fibrous intracellular protein that hardens and protects the cells. What is this protein called?
melanin
keratin
elastin
collagen
keratin
Where are melanocytes primarily located within the skin, and what is their primary physiological function?
a. dermal reticular layer; synthesizing collagen to maintain skin elasticity and tension lines
b. stratum corneum; secreting aqueous sweat to regulate core body temperature
c. hypodermis; storing triglycerides for long-term metabolic insulation
d. stratum basale; producing pigment granules that shield nuclear DNA fro UV radiation
d. stratum basale; producing pigment granules that shield nuclear DNA fro UV radiation
Which epidermal layer gets its name from the microscopic appearance of its cells shrinking during slide preparation while remaining tightly bound by desmosomes?
stratum basale
stratum spinosum
stratum lucidum
stratum granulosum
stratum spinosum
The deeper 80% of the dermis is composed of dense irregular connective tissue and provides structural strength and elasticity. What is the name of this specific layer?
papillary layer
hypodermal layer
reticular layer
basal layer
reticular layer
Which tissue layer lies deep to the dermis, serving as an energy reservoir, shock absorber, and thermal insulator, and what primary cell type does it contain?
hypodermis; composed predominantly of adipocytes
papillary dermis; composed of loose areolar connective tissue with fibroblasts
stratum basale; composed of simple columnar keratinocytes
reticular dermis; composed of dense regular fibrous tissue
hypodermis; composed predominantly of adipocytes
Sebaceous glands are typically associated with hair follicles and secrete an oily, lipid-rich substance that lubricates hair and skin. What is this secretion called and what type of release mechanism is used?
sweat; eccrine secretion via active transport channels
cerumen; apocrine secretion involving pinching off of the apical cell membrane
sebum; merocrine secretion involving direct exocytosis of vesicles
sebum; holocrine secretion where entire cells rupture to release their product
sebum; holocrine secretion where entire cells rupture to release their product
When exposed to cold temperatures or emotional stimuli, what specific muscle type contracts to pull hair follicles upright, producing "goosebumps"?
skeletal muscle attached to the hypodermal fascia
smooth muscle known as the arrector pili
cardiac muscle fibers embedded within the deep dermis
smooth muscle forming the endothelial walls of dermal arterioles
smooth muscle known as the arrector pili
The stratum lucidum is a clear, flat, dead layer of keratinocytes found exclusively in which specific anatomical regions of the human body?
areas with dense hair follicles such as the scalp and eyebrows
high friction areas of the face and neck
thick skin regions, such as the palms of hands and soles of feet
thin skin areas covering the abdomen and back
thick skin regions, such as the palms of hands and soles of feet