Intervertebral Discs Disease and Degenerative Disc Disease (DDD) Review

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A set of vocabulary flashcards covering the etiology, pathophysiology, clinical manifestations, diagnosis, and treatment of Intervertebral Disc Disease and DDD.

Last updated 9:45 PM on 5/14/26
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15 Terms

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Intervertebral discs

Structures that separate vertebrae and provide shock absorption to the spine and body.

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Degenerative disc disease (DDD)

A condition characterized by the loss of elasticity, flexibility, and shock-absorbing capabilities of the intervertebral discs.

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Nucleus pulposus

The center part of the intervertebral disc that thins and dries out in DDD, potentially leading to herniation.

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Radiculopathy

A condition involving radiating pain, numbness, tingling, or decreased strength and range of motion, often associated with osteoarthritis of the spine.

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Low back pain

The most common clinical manifestation of intervertebral disc disease or DDD.

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Paresthesias

Numbness or tingling sensations, specifically in the legs, associated with intervertebral disc disease.

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Cauda equina compression

Compression of multiple nerve roots resulting in bowel and bladder incontinence; it is considered a medical emergency.

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Cervical disc disease

Disease of the discs in the neck where pain radiates to the arms and hands, often resulting in decreased reflexes and handgrip strength.

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Diagnostic tests for disc disease

Methods including X-rays, Myelogram, MRI, CT scan, Epidural venogram, discogram, and EMG.

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Transcutaneous electrical nerve stimulation (TENS)

A form of non-surgical conservative therapy used to manage intervertebral disc disease.

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Drug therapy for disc disease

Medications including NSAIDs, short-term opioids, muscle relaxants, antiseizure drugs, antidepressants, and epidural corticosteroid injections.

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Radiofrequency discal nucleoplasty

A surgical procedure where a radiofrequency probe generates energy to break up the nucleus pulposus, removing up to 20%20\% of it.

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Laminectomy

The surgical removal of a disc through an excision in part of the vertebra.

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Discectomy

The surgical decompression of a nerve root using microsurgical or percutaneous techniques.

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Charit or Prodisc-L

Specific types of artificial discs used for replacement in lumbar DDD that allow for movement at the level of the implant.