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true (absolute) dead space
ventilation, no perfusion
clinical example of true deadspace
pulmonary embolism and low cardiac output
anatomic deadspace
no gas exchange (conducting airway)
clinical example of of anatomic deadspace
shallow breathing
relative deadspace
more ventilation than perfusion
clinical example of relative deadspace
mechanical ventilatilator and copd
formula for physiologic deadspace
paco2 - pEco2 / paco2 = %
normal spontaenously breathing
< 40%
normal mechanical breathing
< 60%
external respiration
the exchange of o2 and co2 between the alveoli and pulmonary capillaries
o2 transport
transport of o2 from pulmonary capillaries to the cellular destination
internal respiration
diffusion of o2 from small systemic capillaries for metabolic needs
ventilation
the movement of air into and out of the lungs
v/q normal value
0.8
which lung segments have greater ventilation than perfusion
apicoles
which lung segments have greater perfusion than ventilation
base
which lung segment have the greatest amount of perfusion
base
which lung segments have the greatest amount of ventilation?
base
is there a greater amount of perfusion or ventilation in the bases
perfusion
does o2 help v/q mismatch
yes
clinical
FRC definition
volume of gas remaining in the lungs following a normal exhalation
cardiac output
the volume of blood ejected by the heart each minute
CO normal range
4-8 LPMal
alveolar minute ventilation abbreviation
VA
VA defintion
the volume of fresh gas reaching the alveoli each minute
VA equation
(VT - VD) X RR
PVR definition
pulmonary vascular resistance (right sided heart problem)
the pulmonary vessels are the only blood vessels in
the body that react to low o2 levels by constricting rather than dilating
PVR are caused by
hypoxemia, acidemia, pulmonary fibrosis
mechanical deadspace
remaining exhaled gas when connected to some type of appliance
physiologic deadspace
the sum of alveolar and anatomic deadspace
when ventilation is excessive and the paco2 remains high or normal
increased physiologic deadspace should be suspected
Petco2
end tital partial pressure of co2
pEco2
mean expired gas sample
how to determine PECO2
douglas bag
silent unit
no ventilation and no perfusion
As the patient increases their minute ventilation, what should happen to the PaCO2 value
Get lower
If my patient's minute ventilation is 20 L/min (they are very tachypneic) and I obtain an ABG (arterial blood gas), and the results show a PaCO2 value that is normal or high. What should the respiratory therapist suspect?
Physiologic Deadspace
Normal Anatomic Shunting is approximately what percent of the cardiac output?
2%
True or False- Deadspace results in hypoxemia?
False
True or False- Shunting tends to cause primary hypoxemia
true
What are the units for CaO2, CvO2, and CcO2?
vol%
What's the normal shut value?
10%
What's the normal difference between the CaO2 and CvO2?
5 vol%
Congenital heart defects can cause?
Anatomic Shunting
The largest volume of oxygen is carried in the blood how?
Combined with hemoglobin
The volume of fresh gas reaching the alveoli each minute is called?
Alveolar Minute Ventilation
The volume of gas remaining in the lungs after a normal exhalation is called?
Functional Residual Capacity (FRC)
What is the normal range for Cardiac Output?
4-8 L/min
The diffusion of oxygen from small systemic capillaries in response to cellular metabolic needs is called?
Internal Respiration
The exchange of oxygen and carbon dioxide between the alveoli and the pulmonary capillaries is called?
External Respiration
What's the normal Hb level for a woman?
13-14 g%
What's the normal hemoglobin for a male?
15 g%
What's the normal Hct (hematocrit) for a woman?
42%
What's the normal Hct (hematocrit) for a male?
47%
Define ventilation
The movement of air in and out of the lungs.
Which arterial blood gas value (ABG) assesses the adequacy of ventilation?
PaCO2
Define PaO2
Partial pressure of oxygen in the arterial blood
What's the normal PaO2 range?
80-100 mm Hg
Define the term PaCO2
Partial pressure of carbon dioxide in the arterial blood
normal PaCO2 value
35-45mmhg
What's the normal SvO2 value?
75%
What's the normal range for PvO2?
35-45 mm Hg
What's the formula for Alveolar Minute Ventilation?
Respiratory Rate x (Tidal Volume - Deadspace Volume)
What are the units for alveolar minute ventilation?
L/min
What's the normal V/Q ratio?
0.8
What's the normal V/Q range?
0.6-3.3
Which lung segments have a higher V/Q ratio?
Apical segments
Which lung segments have a lower V/Q ratio?
Bases
Which lung segments have greater ventilation; apical or bases?
Bases
Which lung segments have greater perfusion; apical or bases?
Bases
Is there more VENTILATION or PERFUSION in the lung bases?
Perfusion
When you have ventilation but NO perfusion
True Deadspace
When you have both perfusion and ventilation but there is more ventilation than perfusion.
Relative Deadspace
Which type of Deadspace is in the purely conducting airways?
Anatomic Deadspace
Give a clinical example that has a low V/Q ratio
Atelectasis
Give a clinical example that has a high V/Q ratio
Pulmonary Embolism
What does PVR stand for?
Pulmonary Vascular Resistance
This is when there is low oxygen in the bloodstream
Hypoxemia
This is when there is low amount of oxygen getting to cells or tissues
Hypoxia
Name the type of Deadspace where you combine both Anatomical and Alveolar Deadspace?
Physiological Deadspace
The normal Physiologic Deadspace value for a spontaneous breathing patient is?
less than 40%
What's the formula for Physiological Deadspace?
PaCO2-PECO2/PaCO2
What does PECO2 stand for?
Mean expired CO2
How do you collect PECO2?
With the Douglas Bag on the expiratory side of the vent circuit.
What's the Physiologic Deadspace value for a patient on a mechanical ventilator?
less than 60%
The normal difference between the PaCO2 and PetCO2 value is?
1-3 mm Hg
When comparing the PaCO2 and PetCO2 value, which value is always higher?
PaCO2
Clinical situations such as hypotension, decrease in cardiac output and PE are examples of?
Absolute Deadspace
Name a clinical situation that would be an example of Anatomic Deadspace?
Rapid Shallow Breathing
Clinical situations in which there is both perfusion and ventilation but there is more ventilation than perfusion is an example of?
Relative Deadspace
COPD, Mechanical Ventilation are examples of?
Relative Deadspace
This is when you have perfusion but no ventilation.
Absolute Shunting
This is when you have perfusion and ventilation, but you have more perfusion than ventilation.
Relative Shunting
ARDS, Pleural Effusion, Pneumonia, CHF are examples of?
True or Absolute Shunting
Normal range for CaO2
16-20 vol%
Normal range for CcO2
Depends on FiO2 and Hb levels
Normal range for CvO2
12-15 vol%
What's the formula for CcO2?
(Hb x 1.34x SaO2) + (PAO2 x 0.003)