ECEN 414 L5 (Biosensor Characteristics)

Biosensor Characteristics

● Sensitivity
● Limit of Determination
● Background Signal
● Dynamic Range
● Dynamic Response
● Selectivity
● Calibration
● Linearity
● Hysteresis
● Drift and Long-Term Stability
● Temperature Dependence
● Signal to Noise
● Reliability (Accuracy and Precision)
● Resolution
● Lifetime
● Biocompatibility

Sensitivity

Limit of Determination (Detection Limit)

Ideally: It is extremely low, allowing the biosensor to detect minute quantities of the analyte with high precision and accuracy

Practically: It is often higher due to various factors such as noise, interference from other substances, and limitations in the sensor’s design and materials.

Background Signal

Dynamic Range

Dynamic Response (Δr/Δt/Δc)

Selectivity

Calibration

Should be easily calibrated simply by exposing it to prepared standard solutions or gases containing different known concentrations of the target analyte

Hysteresis

Ideal biosensor should not be affected by its past history of measurements, and would have zero ________

Temperature Dependence

Signal to Noise Ratio

• Measure of how much a signal has been corrupted by noise

• Improving ___ in practice

  • Controlled environment

  • When characteristics of noise are known, can use a filter or to process the signal

Reliability (Accuracy, Precision ) and Resolution

Lifetime

Biocompatibility

Relevant to biosensors that have medical applications