KINE 433: Topic 8

During inspiration, explain the relationship between thoracic volume and lung pressure.

Define tidal volume

Define total lung capacity (including vital capacity and residual volume)

Define IRV

Define ERV

Define FRC

Why is pulmonary pressure lower than arterial pressure? Explain.

List the PO2 and PCO2 values when in the arterial blood and venous blood at normal atmospheric pressure.

What type of pressure gradient across the membrane will result in greater/faster diffusion?

What advantage in diffusion does CO2 have over O2 and why it matters?

What is the (a-v)O2 difference and what does it signify?

Does a greater or smaller (a-v)O2 difference contribute to improved VO2max?

What are the factors that lead to a right shift and left shift in the Oxygen Dissociation Curve? What does each shift represent?

How many grams of Hb per 100 ml of blood is the average for a human?

How many grams of Hb per 100 ml do we see in women and men?

Describe and explain the Bohr and Haldane effects.

What are the three primary ways CO2 is expelled?

How does low PO2 in the mitochondria and PCO2 difference between muscles and capillaries facilitate O2 and CO2 transfer between tissues?

How does high PO2 in the lungs and low PCO2 in the alveoli facilitate reoxygenation of blood and expiration of CO2

Where is 2,3-diphosphoglycerate found and why it is important to O2 delivery?