Persistence of memory cells

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5 Terms

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How do naïve lymphocytes obtain survival signals?

Through their T-cell receptor or membrane immunoglobulins.

2
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Do memory lymphocytes require survival signals?

They do not seem to require survival signals for long-term survival.

3
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What can provide survival signals to subsets of memory lymphocytes?

Secreted cytokines.

4
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Which cytokines promote the survival of CD8+ memory T cells?

IL-7 and IL-15.

5
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Do CD8+ memory T cells need T-cell receptor engagement for survival?

No, IL-7 and IL-15 can support their survival without T-cell receptor engagement.