Health Informatics 4

BLAST (Basic Local Alignment Search Tool)

Helps compare gene sequences.

Human Genome Project

Provides complete human genetic information.

NCBI (National Center for Biotechnology Information)

Central hub for biological databases.

A tool used to compare an input DNA or protein sequence against known sequences in a database.

BLAST

Mapped the entire human genome. Provided a complete reference sequence of human DNA.

The Human Genome Project (1990-2003)

Provides access to GenBank, BLAST, PubMed, and other resources. Supports research in genetics, medicine, and molecular biology.

National Center for Biotechnology Information

1950s-1960s

Early computational biology began with protein sequencing.

1977

Frederick Sanger developed the first DNA sequencing method.

1980s

Development of biological databases such as GenBank.

1990

The Human Genome Project was launched to map the human genome.

2003

Completion of the Human Genome Project, providing the full human genetic blueprint.

2012

CRISPR-Cas9 gene-editing technology revolutionized genetic engineering.

2015

Precision medicine initiative launched, leveraging bioinformatics for targeted therapies.

2020s

AI and machine learning integrated into bioinformatics, advancing drug discovery and genomics.

Bioimaging informatics

The interdisciplinary field that applies computational techniques to analyze, enhance, and interpret biological and medical images.

Radiology

AI-assisted interpretation of X-rays, CT scans, and MRIs.

Pathology

Digital pathology uses AI to detect abnormalities in tissue samples.

Ophthalmology

Retinal imaging for diagnosing diabetic retinopathy.

Augmented Reality in Surgery

Real-time imaging guides surgeons during complex procedures.

Robot-assisted Surgery

Enhances precision and reduces invasiveness.

Structural Imaging

Focuses on capturing the anatomical structure of organs and tissues.

Functional Imaging

Measures physiological and metabolic activities in the body.

Molecular Imaging

Captures cellular and molecular processes within tissues.

AI-Assisted Imaging

Uses deep learning to enhance and interpret images.

Image Processing Software

MATLAB, ImageJ, Fiji

Cloud-Based Medical Image Databases

Its a hospital imaging storage.