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Psychoanalytic Perspective
Sigmund Freud develops psychoanalytic approach to treat patients with psychological problems, focusing on how unconscious factors (drives, conflicts from childhood) impact human development and behaviour.
Behaviourist Perspective
Emphasizes scientific study of observable action, founded by John Watson (1920) building off of Ivan Pavlov who studied classically conditioned fear. BF Skinner studied impact of reinforcement and punishment on behaviour in studies on operant conditioning.
Humanistic Perspective
Takes holistic approach of individual, emphasizing higher aspects of nature. Abraham Maslow proposed that humans are motivated to achieve needs in a hierarchy of importance, with the highest level being self-actualization (fulfilling one's greatest potential). Carl Rogers introduced the concept of unconditional positive regard (acceptance and support).
Hypothesis
Testable explanation for a phenomenon.
Alternative Hypothesis
Based on prior evidence and assumes that a significant relationship or difference exists between variables, predicting the nature of that relationship or difference.
Null Hypothesis
The inverse of the alternative hypothesis, stating that there is no significant difference or relationship between variables.
Independent Variable
Manipulated by the experimenter to determine if changes to it impact the dependent variable.
Dependent Variable
The outcome that is measured in an experiment.
Correlational Studies
Studies that examine the relationship between variables but cannot demonstrate cause and effect as no variables are manipulated.
Experimental Studies
Researcher manipulates the independent variable to determine its impact on the dependent variable or outcome, showing a cause and effect relationship.
Placebo
A substance or treatment with no active therapeutic effect, often used in clinical trials to compare against the actual treatment.
Reliability
Extent that experiment can consistently produce similar results.
Validity
Accuracy of study or measure.
Internal validity
Extent to which measure of experiment produces true result.
External validity (generalizability)
Extent to which study results can be applied to real life situations.
Informed consent
Process of instructing potential research participants about study, risks, and rights (ex: to withdraw).
Descriptive statistics
Describes dataset with measure of central tendency (mean, median, mode) and variation (IQR, SD).
Mean
Average data point.
Median
Middle value when data organized in numerical order.
Mode
Most frequently occurring data points.
Range
Difference between lowest and highest data points.
Inferential statistics
Used to draw conclusions that reach beyond sample dataset.
Pearson correlation
Describes linear relationship between two variables.
Positive correlation
Variables increase/decrease together.
Negative correlation
As one variable increases, other decreases.
Zero correlation
Lack of linear relationship between variables.
Afferent neurons
Send signals towards brain.
Efferent neurons
Carry messages away from brain.
Gray matter
Unmyelinated axons, neuronal cell bodies, dendrites.
White matter
Consists of myelinated axons that allow for long distance communication between neurons.
Somatic Nervous System
Sensory neurons that relay information from body to CNS and motor neurons that relay command from CNS.
Autonomic Nervous System
Controls subconscious, not subject to voluntary control.
sympathetic
helps body prepare for stressors
parasympathetic
allows body to return to homeostasis
Functions of sympathetic
Dilates pupil, inhibits salivation, accelerates heartbeat, dilates bronchi, inhibits digestion, stimulates glucose release, inhibits gallbladder, secretes epi and norepi, inhibits intestinal activity, relaxes bladder, promotes ejaculation and vaginal contraction
Functions of parasympathetic
Constrict pupils, stimulates salivation, slows heartbeat, constricts bronchi, stimulates digestion, inhibits glucose release, stimulates gallbladder, stimulates intestinal activity, contracts bladder, promotes erection of genitals
neurons
send chemical or electrical signals to other cells
Glial cells
support functions to neurons and nervous system
Parts of the nerve cell
cell body, dendrites, axon terminals
neuron soma (cell body)
stores nucleus which has DNA
dendrites
branches that extend from cell body and receive input from other neurons when neurotransmitters bind to postsynaptic receptors on dendrites
Axon terminal
end of axon at synapse
action potential
electrical signal that travels down axons and causes release of neurotransmitters from axon terminal
Neuron myelination
layer wrapped around axons; Myelin is lipid, multilayered continuous along length of axon, interrupted at nodes of ranvier
What happens when action potential reaches axon terminals?
neurotransmitters release into synaptic cleft
Synaptic cleft
junction formed between axon terminal of presynaptic neuron and dendrites of postsynaptic neuron
Role of glial cells
structural and chemical buffering support for neurons, make CSF, immune cells
Communication between neurons
involves action potential
Membrane potential
unequal concentration of charged ions between inside and outside of all living cells
Resting membrane
high concentration of potassium ions and low concentration of sodium ions inside neurons
Result of ionic movement
postsynaptic depolarization (excitation) or hyperpolarization (inhibition)
excitatory postsynaptic potential (EPSP)
binding membrane potential closer to threshold increases likelihood of action potential
inhibitory postsynaptic potential (IPSP)
brings membrane potential further from threshold and decreases likelihood of AP
Components of an action potential
At rest: postsynaptic Na+ channels closed but if stimulus opens, Na+ ions enter cell, causing membrane to depolarize. If depolarization is enough to reach certain threshold, action potential initiated in neuron. If threshold reached, additional Na+ channels open causing rapid depolarization. Repolarization: Na+ channels inactivate and K+ channels open allowing K+ to rush out of cell and membrane potential becomes negative. Resting membrane potential: restored when K+ and Na+ channels.
Absolute refractory period
Time when no new action potentials can be generated regardless of strength of stimulus because Na+ channels inactive.
Neural transmission rate
Larger diameter axons and axons that are myelinated transmit neural impulses faster than smaller and unmyelinated axons.
Action potentials at axon terminals
Neurotransmitters released from synaptic vesicles into synaptic cleft.
Excitatory synapses
Membrane potential of postsynaptic neuron becomes positive, and if exceeds threshold, action potential initiated.
Inhibitory synapses
Neurotransmitters affect postsynaptic neuron by causing cell's membrane potential to become more negative.
Amino acid neurotransmitters
Gamma aminobutyric acid (GABA)→principal inhibitory neurotransmitter of CNS. Glycine→primarily inhibitory neurotransmitter found in CNS. Glutamate→primary excitatory neurotransmitter of CNS.
Acetylcholine
Neurotransmitter released by somatic motor neurons at neuromuscular junction. Involved in learning and memory, arousal, sleep-wake cycles.
Catecholamines
Neurotransmitters including dopamine, epinephrine, norepinephrine.
Dopamine
Involved in movement, reward, motivation, cognition, involved in schizophrenia, Parkinson's.
Epinephrine and norepinephrine
ANS ⇒ wakefulness, alertness, attention, memory, mood.
Monoaminergic neurotransmitters
Catecholamines and serotonin.
Serotonin
Sleep/wake regulation, mood, appetite.
Endorphins
Peptide hormones that act as neurotransmitters. Opioids produced by body to modulate pain and mood.
Excess neurotransmitters
Get broken down or reabsorbed back into presynaptic neuron through reuptake.
Agonists
Mimic or enhance effects of neurotransmitter.
Antagonists
Block or reduce effects of neurotransmitter.
Regions of the brain
Forebrain, midbrain, hindbrain.
Forebrain
(aka prosencephalon)→has cerebrum, brain's left and right hemisphere. Main forebrain structures→olfactory bulbs, basal ganglia, pineal gland.
Basal ganglia
Initiated voluntary movement.
Pineal gland
Releases melatonin, hormone that causes sleepiness when dark.
Limbic system
A complex set of structures that lies on both sides of the thalamus, right under the cerebrum.
Amygdala
Aggression and fear; stimulation to amygdala causes fear and aggression; damage to amygdala causes lack of fear.
Hypothalamus
Releases hormones and controls pituitary gland's hormone release; coordinates bodily processes like hunger, growth, fight or flight response.
Hippocampus
Learning and memory; formation of explicit memories; damage to hippocampus causes severe memory loss.
Thalamus
Sensation and perception; responsible for processing and relaying sensory information and received information from all senses except olfaction.
Midbrain
Area of brainstem that connects brain and spinal cord; contains superior and inferior colliculi.
Substantia nigra
One of the two areas in the midbrain with large numbers of dopaminergic neurons.
Ventral Tegmental Area (VTA)
Projects to different parts of forebrain; important for reward.
Hindbrain (rhombencephalon)
Made of cerebellum and lower part of brainstem: medulla, pons, reticular formation.
Medulla
Part of the brainstem closest to the medulla; controls critical functions like breathing and heart rate.
Pons
Above medulla; regulates sleeping, waking, dreaming.
Reticular formation
Series of neurons that spans entire brainstem leading to consciousness and wakefulness.
Cerebellum
Coordinates voluntary movements, posture, balance; integrates visual, vestibular, kinesthetic information for balance and posture.
Frontal lobe
Higher order processing; planning, decision, personality, judgement, voluntary movement.
Parietal lobe
Proprioception (awareness of body position in space) and somatosensation (perception of touch, pain, temperature).
Temporal lobe
Auditory cortex; processing auditory stimuli; learning and memory (hippocampus) and language (Wernicke's).
Occipital lobe
Back of cerebral cortex for visual processing; visual cortex processes input from eyes.
Cerebral cortex
Outermost portion of brain divided into frontal, temporal, parietal, occipital lobes.
Prefrontal cortex
Area of frontal lobe for decision making, personality, memory.
Motor cortex
Relays motor commands from motor cortex to skeletal muscle.
Somatosensory cortex
Processes somatosensory information in parietal lobe.
Hemispheric lateralization
Brain's right and left hemispheres specialized for processes.
Corpus callosum
Myelinated axonal projections connecting right and left hemispheres; severed corpus callosum leads to disrupted communication between hemispheres.
Spinal cord
Relays messages between PNS and brain; contains white matter (myelinated) and grey matter (cell bodies, dendrites).
Spinal reflex
Neural process of receiving and acting on sensory information in reflex arc.
Somatosensory receptors
Receptors in skin stimulated by something painful.