Endocrine and Coagulation Labs

Vocabulary flashcards based on the lecture notes provided.

0.4-4.2 μU/mL

Normal TSH range

Hypothyroidism, Hyperthyroidism

TSH levels indicate

80-200 ng/dL

Normal T3 range

Hyperthyroidism, Hypothyroidism

T3 levels indicate

0.8-2.8 ng/dL

Normal free T4 range

10-60 pg/mL

Normal ACTH range

Cushing's disease, Addison's disease

ACTH levels indicate

6-23 mcg/dL

Normal Cortisol (AM) range

Cushing's, Addison's

Cortisol levels indicate

Low

Effect on Serum Na+ in SIADH

High

Effect on Serum Na+ in DI

135-145 mEq/L

Normal Serum Na+ range

High

Effect on Urine Osmolality in SIADH

Low

Effect on Urine Osmolality in DI

300-900 mOsm/kg

Normal Urine Osmolality range

Low

Effect on Serum Osmolality in SIADH

High

Effect on Serum Osmolality in DI

275-295 mOsm/kg

Normal Serum Osmolality range

High (>1.030)

Effect on Urine Specific Gravity in SIADH

Low (<1.005)

Effect on Urine Specific Gravity in DI

1.005-1.030

Normal Urine Specific Gravity range

Low serum Na, concentrated urine

SIADH results in

High serum Na, diluted urine

DI results in

Decreased (thrombocytopenia)

Effect on Platelets in DIC

150,000-400,000/mm³

Normal Platelets range

Increased

Effect on PT in DIC

11-13.5 sec

Normal PT range

Increased

Effect on INR in DIC

0.8-1.1

Normal INR range

2-3

Normal INR range on warfarin

Increased

Effect on aPTT in DIC

25-35 sec

Normal aPTT range

Decreased (used up)

Effect on Fibrinogen in DIC

200-400 mg/dL

Normal Fibrinogen range

Greatly Increased (in clot breakdown)

Effect on D-Dimer in DIC

<0.5 mcg/mL

Normal D-Dimer range

Petechiae, ecchymosis, bleeding gums

Early DIC symptoms

Increased

Effect on Lactate in Sepsis

0.5-2.2 mmol/L

Normal Lactate range

Inflammation

ESR indicates

<20 mm/hr

Normal ESR range

Infection, inflammation

CRP indicates

<1 mg/dL

Normal CRP range

Increased

Effect on Albumin in Dehydration

Decreased

Effect on Albumin in Liver Disease

3.5-5.0 g/dL

Normal Albumin range

T3

Hormone produced by the thyroid gland; regulates metabolism

ACTH

Hormone produced by the pituitary gland that stimulates the adrenal glands

Cushing's disease

A disorder caused by prolonged exposure to high levels of cortisol

Addison's disease

A disorder caused by adrenal gland insufficiency

ADH

A peptide hormone that increases water reabsorption in the kidneys

SIADH

A condition characterized by excessive release of antidiuretic hormone (ADH)

DI

A condition characterized by frequent urination due to the kidneys' inability to conserve fluid

PT

A common test used to help evaluate a person for bleeding disorders

aPTT

A measurement of how long it takes blood to clot

Fibrinogen

A protein produced by the liver that helps in blood clotting

D-dimer

A blood test that measures fibrin degradation products

Sepsis

A serious medical condition caused by an overwhelming infection

Tissue hypoxia

A condition in which the body's tissues are deprived of adequate oxygen supply

ESR

A blood test that measures the sedimentation rate of red blood cells

CRP

A protein made by the liver that increases when there's inflammation in the body

Albumin

A protein made by the liver that helps keep fluid in the bloodstream

Thrombocytopenia

Low platelet count

Petechiae

Tiny purple, red, or brown spots on the skin

Ecchymosis

A discoloration of the skin resulting from bleeding underneath

Urine Osmolality

The measure of the concentration of dissolved particles in urine

Serum Osmolality

The measure of the concentration of dissolved particles in blood

Urine Specific Gravity

A laboratory test that measures the concentration of urine

Serum Na+

The concentration of sodium in serum

Lactate

A waste product produced in muscles during intense exercise

TSH

Hormone that stimulates the thyroid gland to produce T3 and T4

Sodium

Key electrolytes in the body

Pituitary

Related to disorders of the pituitary gland

Coagulation

Used to assess bleeding and clotting disorders

DIC

Disseminated Intravascular Coagulation

INR

A numerical value used to monitor the effectiveness of anticoagulant drugs

Infection

Associated with inflammation and immune response

Dehydration

Also known as edema

Liver disease

May be chronic or acute

Metabolism

Regulates the body's use of energy

Cortisol

Hormone involved in stress response and regulation of blood pressure

Adrenal

A disorder that affects the adrenal glands

Pituitary gland

A gland that produces several hormones

Hormones

A group of hormones that regulate various bodily functions

Specific gravity

A tool to assess the concentration of urine

Bleeding gums

Occurs when the blood doesn't clot normally

Clot breakdown

Important component of coagulation

Renal

An adjective related to kidneys

Pulmonary

Refers to lung function

Cardiac

Refers to heart function

Neurological

A term associated with the nervous system

GI

Related to the gastrointestinal tract

Hematological

Relating to blood

Endocrine

Related to the endocrine system

Muscular

Relating to muscles

Nervous

Relating to nerves

Hyperglycemia

A condition characterized by high blood sugar levels

Hypoglycemia

A condition characterized by low blood sugar levels

Homeostasis

Related to the maintenance of stable internal conditions

Tachycardia

Increased heart rate