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Etiology
the study of the cause of disease
Infection
the growth of microorganisms in the body
Microbial antagonism (aka competitive exclusion)
growth of some microbes prevents the growth of other microbes
pathogens
a disease-causing organism
pathogenesis
the manner in which disease develops
Infectious disease
a disease in which pathogens invade a suseptible host and carry out at least part of their life cycle in the host
symptoms
a change in body function that is felt by a patient as a result of a disease
communicable disease
any disease that can be spread from one host to another
contagious disease
a disease that is easily spread from one person to another
noncommunicable disease
a disease that is not transmitted from one person to another
Incidence
the fraction of the population that contracts a disease during a particular period of time
prevalence
the fraction of a population having a specific disease at a given time
sporadic disease
a disease that occurs occasionally in a population
endemic disease
a disease that is constantly present in a certain population
epidemic disease
a disease acquired by many hosts in a given area in a short time
pandemic disease
an epidemic that occurs worldwide
infection fatality ration
calculated by dividing the number of deaths attributed to a disease by the total number of infected individuals
case fatality ration
the proportion of individuals diagnosed with a disease who die from that disease within a certain period of time
local infection
an infection in which pathogens are limited to a small area of the body
incubation period
the time interval between the actual infection and first appearance of any signs or symptoms of disease
prodromal period
the time following the the incubation period when the first syptomes of illness appear
period of illness
disease is most severe; has characteristic signs and syptomes
period of decline
signs and symptoms of the disease subside
period of convalescence
the recovery period, when the body returns to its pre-disease state
reservoirs of infection
continual source of infection
fomite
a nonliving object that can spread infection
healthcare-associated infectious/nosocomial infections
an infection that develops during a stay at a health care facility and was not present at the time the patient was admitted
epidemiology
the science that studies when and where diseases occur and how they are transmitted
portals of entry
the avenue by which a pathogen gains access to the body
adherence
attachment of a microbe or phagocyte to another’s plasma membrane or other surface
siderophores
bacterial iron-binding protiens
toxin
any poisonous substance produced by a microorganism
hemolysins
an enzyme that lyses red blood cells
portals of exit
the route by which a pathogen leaves the body
signs
a change due to a disease that a person can observe and measure
syndrome
a specific group of signs or syptoms that accompany a disease