PHARM THEROY FINAL

Which drugs increase potassium?"

ACE inhibitors (-pril)
ARBs (-sartan)
Spironolactone

photosensitivity,

Doxycycline, Ciprofloxacin
SMX-TMP (Bactrim)

Hepatotoxic drugs

Statins
Rifampin
INH
Fluconazole

Which are long-term asthma medications

LABA
ICS
Montelukast

Which nursing actions are appropriate for heparin therapy?

Monitor aPTT
Assess for bleeding
Use soft toothbrush
Know antidote (protamine)

TOXICITY

• Neuro

• Cardiac

• Vision

• Nausea

Antidote for Heparin

Protamine

Antidote for Warfarin

Vitamin K

Antidote for Digoxin

Digibind

Antidote for Acetaminophen

N - acetlycysteine Antidote

Antidote for Opines

naloxone

Antidote for Benzos

Flumazenil

Suffix for ACE inhibitors

-Pril

Suffix for ARBs

-Sartan

Suffix for beta Blockers

-Olol

Suffix for CCBs

-Dipine

Suffix for Lipid lowering

-Statin

Suffix for SABA/LABA

-terol

suffix for Anticholinergic inhalers

-pium

Suffix for Leukotriene modifiers

-lukast

Suffix for Fluoroquinolones

-floxacin

Suffix for Tetracyclines

-cycline

Suffix for Tetracyclines

cef-/ceph-

SABA = rescue

salbutamol (Ventolin)

LABA = long-term

salmeterol (Serevent)
MUST be combined with ICS in asthma.

ICS

fluticasone, budesonide
Cause thrush → rinse mouth.

LTRA

montelukast
Nighttime preventer, NOT rescue.

COPD

pratropium / tiotropium (–pium)

Danger drug

Theophylline → seizures + dysrhythmias

Aminoglycosides → gentamicin

Ototoxic + nephrotoxic

Fluoroquinolones → ciprofloxacin

Tendon rupture + photosensitivity

Tetracyclines

Tetracyclines

Rifampin

Orange fluids

INH

B6 deficiency (give pyridoxine)
Peripheral neuropathy

Sulfonamides → SMX-TMP

Increase fluids
Photosensitivity

ACE inhibitor

lisinopril → cough, ↑K⁺

ARB

losartan → no cough, ↑K⁺

Beta blocker

metoprolol → ↓ HR
Avoid in asthma.

CCB

amlodipine → edema + headache

Diuretics

Loop (furosemide) → ↓K⁺

Thiazide → ↓K⁺

Spironolactone → ↑K⁺

Digoxin

Halos, bradycardia

Toxicity ↑ with low potassium
Antidote → Digibind

Nitrates

Headache
DO NOT use with Viagra

Hyperkalemia drugs:

ACE, ARB, spironolactone

Photosensitivity drugs:

Tetracyclines, Fluoroquinolones, SMX-TMP

Liver-toxic drugs:

Statins, INH, Rifampin, Fluconazole

Digoxin toxicity signs:

Nausea, halos, bradycardia, confusion