Stimulants

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Last updated 5:40 PM on 8/27/26
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8 Terms

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Benzoylecgonine

Cocaine metabolite found in highest concentration in urine; can last ~ 3 days after use

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<p>Esterase (found in the liver)</p>

Esterase (found in the liver)

The primary enzyme that metabolizes cocaine

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Smoking → pulmonary veins → left side of heart → aorta → cerebral circulation. Due to bypass of other tissues, this route produces the fastest onset. THIS IS FASTER THAN INJECTION USE.

Method of cocaine use that results in the most rapid delivery to the CNS

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Urinary acidification

This enhances urinary excretion of amphetamines

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2.5 hours

Time to peak for smoking methamphetamine

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15 minutes

Time to peak after injecting methamphetamine

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3 hours

Time to peak after snorting methamphetamine

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CAMK4

Gene involved in higher susceptibility to cocaine use disorder