Immunology 1

Discuss 7 acute phase reactants

Describe cells of the immune system

Describe epitope structure and cross reactivity

Describe major histocompatibility complex and antigen presentation

Discuss characteristics of T cell maturation and antigen recognition.

Describe characteristics and functions of 8 cytokines.

Describe CRP characteristics including origin, role in inflammation, and use as a laboratory test.

List 6 acute phase reactants in addition to CRP.

Describe characteristics of molecules that impact the immunogenicity of epitopes.

Differentiate linear and conformational epitopes.

Explain the mechanism of cross reactivity.

Differentiate the 3 classes of Major Histocompatibility complex

Differentiate the structure and function of the MHC I and MHC II molecules.

Describe the structure and function of T cell Receptor (TRC) molecules.

Discuss the mechanism of antigen presentation by MHC I and MHC II molecules.

List stages and their associated locations for T cell maturation.

Describe positive and negative selection in T cell maturation.

Differentiate the T cell subsets by function and CD markers.

Describe the mechanism and resulting action of antigen recognition by T helper cells.

Describe the mechanism and resulting action of antigen recognition by T cytotoxic cells

Discuss the structure of cytokine molecules with Interleukin 2 as an example.

Associate the cytokines that act as effector molecules with their T cell target.

Describe characteristics including site of production and main function of 8 major cytokines.

Associate 8 major cytokine molecules with their associated type of immunity.