GABA neurones

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9 Terms

1
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what is the most abundant inhibitory neurotransmitter in the brain 

y-aminobutyric acid = GABA

2
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how is GABA synthesised

synthesised from glutamate by glutamic acid decarboxylase

3
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what are neurones that synthesise GABA known as

inhibitory GABAergic neurorones

these neurones send signals to other neurones through inhibitory synapses to suppress activity

4
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what are the 2 types of GABAergic neurones in the brain

  • interneurones

  • projection neurones

5
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what do GABAergic interneurones do

innervate nearby neurones, including excitatory pyramidal neurones and other inhibitory interneurones

6
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how do GABAergic interneurones influence brain activity

by making synapses with many neurones, they control and synchronise activity of large groups of neurones

7
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how many types of interneurones exist within the brain

20

8
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what distinguishes GABAergic projection neurones from interneurones

projection neurones send signals to neurones outside their region unlike interneurones which act locally

9
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example of GABAergic projection neurones

The Medium Spiny Neurones of the Striatum.