Renal function tests

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16 Terms

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Kidney Function

Excretion of waste, maintenance of extracellular fluid volume and composition, including acid-base balance, and hormone synthesis.

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Urinalysis

A laboratory test that involves analyzing urine to assess various health conditions.

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Microalbuminuria

A sensitive test that detects low concentrations of albumin in urine, indicating early nephropathy.

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Proteinuria

The presence of abnormal quantities of protein in urine, indicating potential kidney damage.

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Creatinine

A by-product of muscle energy metabolism and the most reliable test of glomerular function.

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Estimated GFR (eGFR)

An estimate of the glomerular filtration rate derived from plasma creatinine concentrations.

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Cystatin C

A small protein that reflects the GFR more accurately than creatinine, influenced less by muscle mass.

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Beta 2 microglobulin

A protein freely filtered by the glomerulus; a sensitive indicator of renal tubular disease.

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Glycosuria

Presence of glucose in the urine, indicating potential renal tubular malfunction.

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Renal Tubular Function Tests

Tests that assess the function of renal tubules, including glycosuria and amino aciduria.

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Glomerular Proteinuria

Proteinuria caused by increased glomerular permeability, typically seen in chronic kidney disease.

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Creatinine Clearance Formula

A formula (Cx = Ux * V / P) used to estimate the glomerular filtration rate based on urinary creatinine.

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Overflow Proteinuria

Proteinuria due to excess low molecular weight proteins in plasma filtered beyond tubular reabsorption.

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Acute Kidney Injury (AKI)

A rapid decline in kidney function, affecting the accuracy of estimated GFR.

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Chronic Kidney Disease (CKD)

A long-term kidney condition that can be assessed through GFR measurements.

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Renal Function Tests

Tests designed to provide insights into kidney health and function.