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what is a cell
cell is the smallest functional and structural unit capable of carrying out the life processes
what do functional activities of each cell depend on
specific structural properties of the cell
are cells living building blocks of all plant and animal organisms
yes
what do all new cells and new life arise from
preexisting cells
3 componets of a cell
plasma membrane, nucleus, cytoplasm
the plasma membrane bound in the cell is composed of what?
selectively permeable and made of phospholipids
nucleus
contains genetic material (DNA in chromosomes)
Transcription
simply copying a recipe from your DNA's master cookbook into a portable note called mRNA.
translation
is actually cooking the meal; your cell's machinery (ribosomes) reads the mRNA note and builds a functional protein
cytoplasm
portion of the cell outside of the nucleus but contained by plasma membrane, contains organelles and cytosol
what is the other name for the plasma membrane
cell membrane
things the plasma membrane does
surrounds every cell, seperates cell contents (ICF+ECF), controls movement into and out of cell, made of phosolipids
nucleus
enclosed by a double layered nuclear envelope, contains cell's genetic material, DNA, serves as a genetic blueprint during cell replication, directs protein synthesis
cytoplasm
portion of the cell interior not occupied by the nucleus, consists of organelles (little organs), cytosol (complex, gel-like mass in which the cytoskeleton is found)
transcription
taking the DNA into a language the cell can now read
Translation
taking RNA into proteins
examples of organelles
endoplasmic reticulum (ER), free ribosomes, Golgi complex, mitochondrion
endoplasmic reticulum
smooth er, rough er, network that is inside the cell, elaborate fluid filled organelle with lots of membranes distributed throughout the cytosol
Er is also known as the
packaging center
rough ER
surface has ribosomes attached and involved in protein synthesis, most abundent in cells which specialize in protein secretion
Smooth ER
no ribosomes attached, not involved in protein synthesis, helps form transport vesicles, lipid synthesis, detoxification in liver through the smooth ER
vesicle
sphere of phosolipids
transport vesicle
sphere of plasma membrane that moves across the cell that has protein within the cell
secretitory vesicle
a vesicle that will go to the plasma membrane, release the protein into an environment outside of the cell
what does lipid synthesis do
processes cholesterol which makes steroid hormones
why does a rough ER look rough
because of the dots (ribosomes) can assume protien is being made
ribosomes
can be attached to ER but can also be floating either way always making proteins
Golgi complex is known as
the distribution center
funtions of the golgi complex
modifies the proteins secreted by the Er and prepares them for distribution, sorts and directs finsihed products to their final destination
what is the goli complex closely associated with
the ER, which consists of a stack of flattened, curved membrane enclosed sacs called cisternae
what is exocytosis
process that allows the cell to secrete its products
are there ribosomes on the golgi complex
no
desribe excoytosis
the rough er makes proteins puts it into vesicles, then sent to golgi apparatus and gets a label on where to go into a vesicle then it gets released
mitochondria
it makes ATP, energy organelle, contains enqymes for citric acid cycle (krebs cycle) and electron transport chain, enclosed by a double membrane
what is the double membrane enclosed by called
cristae
protein life span
1. bulding blocks the dna strand in nucleus
then receiving division what happens
the DNA is translated into RNA in nucleus which is a language ribosomes can read
next is processing divison which means
ribosomes can translate the RNA into protein
next is packaging divison
protein is packaged into a vesicle in the ER
next is distribution which means
golgi modifies the protien if needed and directs its path to a cell
next it arrives at the cell location or secreted and does it funtion which means it
enables the cell function and secretion
what does celluar energy =
ATP
energy in the cell is used to what
do mechanical things, transport things around the cell and across cell membrane, build things in the cell
what are energy sources
carbohydrates, lipids, protein
anabolic reactions use
energy to build things, and require energy
catabolic reactions breaks
things down those storage molecules and release enery
making ATP
you breakdown molecules and release energy (catabolic reaction) which is converted to ATP which is later used to build new bonds (anabolic reaction)
3 main processes in making ATP
Glycolysis, krebs cycle, electron transport chain
Glycolysis
takes glucose and breaks it down into acids happens in the cytoplasm and aerobically (does not require O2) not a lot of ATP at least 2
Krebs Cycle and electron transport chain require what
(require O2) and are aerobic processes
Electron Transport Chain (ETC)
by products of the krebs cycle and create a bunch of ATP like 3 or 4
what is the requirment for mitochondria to be involved in making ATP
O2
Krebs Cycle
aerobic process, net 2 ATPS from each 3 carbon molecule
what is the lipid bilayer that makes up the plasmic membrane
extremely thin layer of lipids and proteins that forms outer boundary of every cell, and genuinely hydrophobic and hydrophobic
hydophillic
face the inside and outside of cell where water is
hydrophobic
do not like the water so go to the middle of the lipid bilayer
what else does the lipid bilayer do
mechanical barrier to hold the contents of the cell, participates in joining cells to form tissues and organs, plays a role in the ability of a cell to respond to changes of the cell environment
what is the fluid mosaic model
it refers to "fluid" movement of the lipid membrane plus the addition of a protein "mosaic"
where is the cholesterol located in the plasma membrane structure
between phosolipid molecules and contributes to the stability of the cell membrane
what else does the plasma membrane constain
carbohydrates on outer surface only to bound to membrane proteins
membrane proteins are
are attached or inserted within the lipid bilayer and has 6 major functions
what are the 6 major functions of the membrane proteins
channels, carrier problems, docking problems, receptors, call adhesion molecules (CAMS), glycoproteins
where are intergral proteins located
firmly inserted into and extend across the lipid bilayer and go across entire cell membrane
where are peripheral proteins located
loosely lie on the inner and outer surface of the cell membrane
what are channels
intergral proteins and across entire membrane and create a tunnel and allow passage of small things, may be opened or closed and depends on weather there charged
what does a charged molecule mean
it means its hydrophilic and like water which will create a channel to get through
carrier proteins
intergral proteins and across the membrane, involved with carrier mediated transport, specific for larger molecules, carries large molecules
docking proteins
located on the inner surface and where secretory vesicles bind prior to exocytosis
receptos
it binds with specific molecules in the cells environment, specific cells have specific receptors
CAMS
connect cells together and bind tightly side by side each other to hold tissue together, proteins that stick outside cell
glycoprotein
sugar and a protein stuck together, usually peripheral proteins, proteins attached to carbohydrate-usually used for a cell recognition, recognition of target cells
what happens when membrane proteins do not work
autoimmune disorder happen (cystic fibrosis) a channel will not let epithelial tissue go through so it clogs and makes mucus in the lungs
what can genetic defects cause
genetic defects causes a defective protein which means the structure is messed up up and everything else will be messed up
cell to cell adhesions
bind groups of cells into tissues and package them into organsm once arranged they all head together
what are cell to cell adhesions binded together by
extracellular matrix (biological glue), CAMS in cells plasma membranes, specialized cell juntions
what are the types of cell junctions
tight junctions, and gap junctions
tight juntions hold
the cell together and create a seal
gap juntions are
a hole between 2 cells and help the cell communicate
tight junctions functions
bond adjacent cells tg, seal off the passageway between 2 cells, and prevent undesirable leaks within the epithelial sheets
tight junctions are found in
sheets of ephithlial tissue
gap junction functions
small connecting tunnels form by connexons, abundant in particular cells that want to transport electricity (ex: muscles)
in non muscle tissue what do gap junctions permit
unrestricted passage of small nutrient molecules
what forces are associated with transport
active and passive transport
what determines if the cell can cross the membrane
its size and its solubility, and weather its charged (uncharged and non-polar does not like water can go through lipid membrane)
what molecule that is nonpolar can still pass through membranes
H2O
is the cell membrane selectively permeable
yes
what does permeable mean
substance can cross membrane
what does impermeable mean
substance can not cross membrane
passive transport
does not require energy (ATP)
active transport
requires energy (ATP)
what is diffusion
passive movement of molecules move from area of high concentration to area of low concentration
is diffusion crucial to survive every cell
yes
what does diffusion play an important role in
substance entering and leaving the cell, exchange of O2 and CO2 between blood and air in lungs, movement of substances across kidney tubules
eventually what is produced after diffusion
equilibrium
ficks law of diffusion
1. Magnitude, 2. Permeability, 3. surface area of the membrane, 4. molecular weight, 5. distance
osmosis
passive diffusion of water, net diffusion of water down its own concentration gradient (water moves towards solute)
when is osmosis significant
when solutions are infused into our blood
what solution = our cells and tissues and if not used correctly what can happen
0.9% NaCl if not thus our cells can lose water or gain water and swel
isotonic solution
has the same concentration of non-penetrating solutes as normal body cells
hypotonic solution
has a lower concentration of non-penetrating solutes than normal body cells