Immunology & Serology - PRELIM

3rd Year - 1st Semester

Immunology

This deals with the study of the immune system and its components, characteristics, immune responses, and its functions.

Serology

This deals with the diagnostic identification of antibodies and antigens in the serum.

Immunology

This can be defined as the study of a host’s reactions when foreign substances are introduced into the body.

Antigens

Such foreign substances that may or may not induce a host response are called?

Immunogens

These are foreign substances that always induce a host response.

Immunity

This is the condition of being resistant to infection.

Variolation

A method developed in China and Turkey in the 15th century wherein powder made from smallpox scabs were inhaled to produce immunity, but had a fatality of 30%.

Lady Mary Wortley Montagu

Who observed variolation?

Edward Jenner

Made the vaccine against smallpox.

Edward Jenner

Discovered cross-reactivity.

James Phipps

To whom did Edward Jenner first inoculate cowpox samples?

vacca

The word ‘vaccine’ came from what Latin word meaning “cow?”

Louis Pasteur

The Father of Immunology.

Louis Pasteur

Made the rabies, anthrax, and cholera vaccines.

Louis Pasteur

Discovered the principle of attenuation and established the germ theory.

Mumps, Measles, Rubella

MMR attenuated vaccine meaning

Haeckel, 1862

Phagocytosis (name of proponent, year)

Jules Bordet

Complement (name of proponent)

Emil von Behring

Serum antitoxins (name of proponent)

Almroth Wright

Opsonization; opsonins (name of proponent)

Paul Ehrlich

Immunity (name of proponent)

Karl Landsteiner

Human blood group antigens (name of proponent)

James Salk, Albert Sabin

Polio vaccine (name of proponents - 2)

James Salk

Intramuscular polio vaccine (name of proponent)

Albert Sabin

Oral polio vaccine (name of proponent)

Gerald Edelman, Rodney Porter

Antibody structure (name of proponents - 2)

Rosalyn Yallow

Radioimmunoassay (name of proponent)

George Snell, Jean Dausset, Baruj Benacerraf

Major Histocompatibility Complex (name of proponents - 3)

Susumu Tonegawa

Antibody diversity (name of proponent)

Edward Donall Thomas, Joseph Murray

Transplantation (name of proponents - 2)

Ian Frazer

HPV vaccine (name of proponent)

Katalin Kariko, Drew Weissman

COVID-19 mRNA vaccine (name of proponents - 2)

Recognition

Of the 5Rs, which describes: self vs non-self

Response

Of the 5Rs, which describes: react appropriately to what is recognized

Regulation

Of the 5Rs, which describes: ensuring control of the response

Recall

Of the 5Rs, which describes: retaining information about prior infections

Repair

Of the 5Rs, which describes: tissue healing and preservation of functional integrity