Pharmacokinetics: Multiple-Dosage Regimens (II)

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5 Terms

1
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What are both C max and C min?

  • Directly proportional to the dose D0

  • Indirectly proportional to the volume of distribution

2
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Steady state levels increase rapidly if the value of the product ke*T is

Decreasing below about 0.7

3
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There is significant accumulation if the dosing interval is?

Shorter than the half-life (T<t1/2)

4
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The minimum plasma concentration is achieved for?

t=T

5
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