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how many haploid spermatocytes are involved in fertilization
23 (either X or Y)
how many haploid oocytes are invovled in fertilization
23 (all x)
how many total diploids are involved in fertilization
46 (fertilized egg)
how many pairs of chromosome determine sex
one
how many non sex chromosomes are there
23
what is the fertilization process
egg travels alone tube
egg lives up to 24 hours
sperm travels up uterus
sperm reaches egg in 5 min
100-200 sperm reach egg
sperm lives up to 5 days
what is the most common site of fertilization
ampulla
what are the phases of chemical reactions for fertilization
capacitation
acrosome reaction
fusion
what happens during capacitation
physiological and biochemical change of head of sperm before entering the egg
what happens during the acrosome reaction phase
sperm releases enzymes to penetrate the corona radiate and zona pellucida of the oocyte
what does fusion occur between
oocyte and sperm plasma membrane
what happens during the zona reaction
enzymatic reaction changes to block other sperm
what is produced when fertilizatoin occurs
zygote
what happens during cleavage
division of cells
what happens in the morula during cleavage
16 cells after 72 hours
what is the order of forms during fertilization
zygote
morula
blastocyte
implantation
describe a blastocyst
morula forms cavity and fills up with fluid
what do trophoblast cells do
secrete HCG
what does the HCG feedback go to
corpus luteum
what does the HCG feedback loop do
maintain the endometrium
how often do HCG levels double in the first trimester
every 24 hours
what forms on the inner mass
embryonic disc
when does implantation occur
7th day after fertilization
where is the ideal site of implantation
posterior superior fundus
what kind of cells embed into the endometrium
trophoblast cells
what happens during nidation
trophoblast buries itself into the decidua
trophoblast cells split into 2 different tissues
how many tissues do the trophoblast cells split into
placenta membrane
fetal membranes
where is the syncytiotrophoblastic layer
outer layer of placental membrane
what does the syncytiotrophoblast layer invade
decidua
what does teh syncytiotrophoblast layer form
pool filled with maternal blood
what is the syncytiotrophoblast layer called
lacunae
what is the placental membrane
syncytiotrophoblast layer
what is the fetal membrane
cytotrophoblast layer
where is the cytotrophoblast layer
inner layer of the fetus
what does teh cytotrophoblast layer form
chorionic villi
villi deep into the lacunae
what does nitabuchs layer prevent
further digestion of the decidua/endometrium
what do the amnion and chorion fuse to form
aminochorionic membrane
what makes up the aminochorionic membrane
amnion and chorion
when is the placental fully formed by
14 weeks of gestation
how long does the placenta work for
40 weeks
do fetal and maternal blood mix
no
what does the placenta form
cotyledons
what is the placenta the site of
nutrient, gas, and waste exchange
what does simple diffusion exchange
CO2 and O2
what does facilitative diffusion require
need a carrier like glucose
what does active transport exchange
amino acids and proteins
goes against gradient and requires energy
what does pinocytosis transport
cholesterol
IGg
when do HCG levels decrease in the placenta
during second trimester
what hormones does the placenta secrete
progesterone
estrogen
where is the amniotic membrane
innermost membrane
encloses the fetus
what are the characteristics of the amniotic membrane
smooth
encloses fetus
contains amniotic fluid
connect with fetus at umbilicus
what is the function of amniotic fluid
protect fetus against injury
sterile
maintain fetal temperature
allow fetal movement
avoid adhesions of fetus on membrane
receive waste
what is the fluid turnover rate for amniotic fluid
3 hours
what is amniotic fluid derived from
amniotic cell but also maternal blood
what is polyhydraminia
>2 liters of amniotic fluid
GI and other malformations
what is oligohydramnios
<1 liter
fetal renal abnormalities
what does the umbilical cord contain
2 umbilical arteries
1 umbilical vein
what do the umbilical arteries carry
CO2
what does teh umbilical vein carry
O2
what surrounds teh umbilical vessels
wartons jelly
what is teh umbilical cord
pliable cord made of connective tissue
what is the approximate size of the umbilical cord
20 inches long
2 cm wide