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Sympathetic receptor types
adrenergic, alpha one and two, beta one and two
action of alpha 2 adrenergic receptor
lowers NT at presynaptic terminal
action of beta 2 adrenergic receptor
vasodilation, bronchodilation, uterus relaxation, tremor
sympathetic nervous system nickname
fight or flight
which part of the spine do sympathetic neurons branch out from?
lateral horn
what levels of the spinal cord are sympathetic neurons branching from
T1 to L2
the preganglionic and postganglionic neurons synapse in
the paravertebral ganglion
white ramus
B fibers, preganglionic neurons, myelinated
Action of alpha one adrenergic receptor
vasoconstriction, pupil dilation, uterus contraction
action of beta one adrenergic receptor
increases heart rate, releases renin
grey ramus
C fibers, postganglionic neurons, nonmyelinated
prevertebral sympathetic ganglia
ganglia not near spine, spread all over abdomen
sympathetic preganglionic neuron is
short
Nt and receptor in between sympathetic pre and post ganglionic neuron
ACh and nNAChR
NT released into tissue by sympathetic postganglionic neuron
norepinepherine
tissue receptor for sympathetic nervous system
adrenergic
NT and receptor between preganglionic neuron and adrenal medulla in sympathetic
ACh, nNACh
hormone released by adrenal medulla in sympathetic
epinepherine
synthesis of catecholamines
tyrosine->L-DOPA->dopamine->norepinephrine->epinephrine
3 catecholamines
dopamine, norepinephrine, epinephrine
3 things that remove NT
diffusion, uptake, enzymatic breakdown
monoamine oxidase breaks down what and where
NE/E broken down in postganglionic axon
how is norepinephrine taken back up into the cell
Na+ cotransporter carries NE with Na+ gradient
what does catechol-O-methyl transferase break down
E/NE circulating in blood
VMAT
vesicle monoamine transporter, transports NE out of postganglionic axon