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What is the primary genotypic effect of inbreeding on a population?
It causes a genome-wide increase in homozygosity and a corresponding decrease in heterozygosity.
Why does an increase in homozygosity lead to a reduction in fitness?
Related individuals are highly likely to carry the same rare, deleterious recessive alleles inherited from a common ancestor
What is the Dominance Hypothesis of inbreeding depression?
It states that fitness decreases because increased homozygosity unmasks and exposes harmful recessive alleles to natural selection.
Which traits are usually most severely impacted by inbreeding depression?
Traits directly associated with fitness, such as reproduction (fertility, litter size) and survival (juvenile mortality, disease resistance)
What is the Overdominance Hypothesis of inbreeding depression?
It states that fitness decreases because of the loss of heterozygote advantage. Individuals lose the superior performance or environmental adaptability provided by having two different alleles.