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Observational Study
treatments ARE NOT assigned by the researcher
Experiment
treatments ARE randomly assigned by the researcher
Response Variable
a variable that measure the OUTCOME of a study (must be measurable/ quantifiable)
Confounding Variable
a variable that relates to both the independent and dependent variable
Population
entire group of inviduals we want information about
Census
collect data from every individual in the population
Sample
A subset of inviduals from the popualtion we collect data from
Sampling Frame
the physical list og the population used to select the random sample
Simple Random Sample
Every group of n individuals in the population has an equal chance of being selected as the sample
How to take an SRS
State how you will number the population
State the method you will use (random number generator)
State the range of numbers used and how many you will select. Also, communicate how no repeated numbers are allowed.
Systematic Random Sample
Select a random starting place on the sampling frame. Then select every kth item.
k= total/sample needed
Stratified Random Sample
Group individuals so that within a group individuals are similar with a respect to a confounding variable. Then, take a randome sample from each group.
Take a sample that is porportional to the population size
EX: if the group is 50% of the total population, take 50% of the group
Cluster Random Sample
Group individuals located close to one another. Randomly select some clusters as a whole to be the sample. Ignore clusters not chose.
Bias
when a sample is very likely to underestimate or overestimate the population valueyou are trying ot estimate
Selection Bias (Undrcoverage Bias)
occurs when some members of the population are less likely to be chosen or cannot be chosen in a single smaple.
Sample was poorly selected because :
No Randomness Was Used
Convenience Sampling
the sample is selected by what is convenient for the researcher
Voluntary Response Sampling
This is where the individuals choose to respond. The people who respond are often similar to each other with respect to their views/opinions.
Nonresponse Bias
occurs when several individuals are chosen for the sample can’t be contacted or refuse to participate
Response Bias
occurs when there is a systematic pattern of inaccurate answers
Leading Question
People know what answer you want so they tell you that answer
Confusing Questions
People don’t understand the question, so they give an inaccurate answer
Experimental Units/Subjects
The individuals on which the experiment is done:
Subjects = Humans
Units = Anything non-human
Explanatory Variable
A variable whose levels are manipulated intentionally (independent variable)
Levels
The subcatergories/values a factor breaks down into
Treatments
All combinations that can be made when each level of a factor is combined with each level of the other factors
What makes a well-designed experiment?
Comparison
Random Assignment
Control
Replication
Comparison
Must compare two or more treatment groups
What can one of the groups be for a comparison to occur?
A control/ placebo group
Random Assignment
Experimental Subjects/Units have to be randomly assigned to treatments
Control
Control potential confounding variables by keeping all other variables constant for all groups. Could use blinds to accomplish
Single Blind
Either the subjects or the members of the research team, but not both, don’t know which treatment the sibject is receiving
Double-Blind
Neither the subjects nor the members of the research team who have contact with the subjects kniw which treatment the subject is receiving. One (or more researchers who don’t have contact wih subjects will know so that data can be analyzed)
Replication
Must have more than one experimental unit/subject in each treatment
Completely Randomized Design
Most basic design
Take whole group of subjects and use a random method to assign them into treatment groups
How do you make a completely randomized experiment?
Number the subjects from 1- end of sampling frame
Use a random number generator to choose n unique random numbers from sampling frame
Assiign chosen numbers into treatments
Track data
Randomized Block Design
separate subjects into groups first
randomly assign subjects to treatments from those groups
How would you conduct a block design experiment?
Block the subjects based on the confounding variable (ex. age: 20 -30, 30 - 40)'
Number the subjects in the first group by sampling frame
Use a random number generator to generate n uniquerandom numbers from sampling frame
Assign given number into treatment groups
Repeat for other group(s)
Mathced Pair Design (Similar Subjects)
two subjects are paired together such that they are similar with respect to the blocking variable
one subject receives treatment 1, the other subject receives treatment 2
Matched Pair Design (both - both)
Treatments are done in random order so that each subject does both treatments
What do observational studies reveal?
Association between variables, not causation.
What do experiments reveal?
Causation between variables, due to controlled conditions.
You can only generalize the findings of a study to the population from which the sample was selected from.
Observational Studies
Results can be generalized to others who are similar to the volunteers
Well-Designed Experiments