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To add phosphate groups onto proteins
What is the function of a protein kinase?
They are lipid-soluble
What property defines most ligands for intracellular receptors?
signal amplification.
A small number of cell surface receptors can ultimately generate a large intracellular response due to activation of kinase cascades. This is referred to as:
binary fission
In bacterial cell division, the cell divides into two nearly equal halves. This process is called:
homologous chromosomes
The two copies of each type of chromosome found in normal somatic (body) cells in an organism, throughout the cell cycle are called:
16
If there are 32 sister chromatids in a normal somatic cell, how many chromosomes are there?
G1 to S to G2 to mitosis to cytokinesis
What is the sequence of events in a typical eukaryotic cell cycle?
interphase
What is the portion of the cell cycle during which the chromosomes are invisible under the light microscope because they are not yet condensed?
If they cannot, it suggests that they aren't properly attached to the spindle microtubules, and thus won't separate properly during anaphase.
Why is it so important that all of the chromosomes align on the metaphase plate during metaphase?
Cyclins
The progress of the eukaryotic cell cycle is regulated primarily by what proteins?
Meiosis
______ is a process of nuclear division which reduces the number of chromosomes per cell from 2 sets to 1 set.
meiosis
In life cycles that alternate between haploid and diploid stages, fertilization doubles the number of chromosomes per cell while ______ reduces it in half.
crossing over
Homologous chromosomes pair along their length during prophase I of meiosis. While two homologues are paired, genetic exchange may occur between them in a process called ________.
two
Diploid organisms use meiosis to produce haploid cells. Meiosis consists of how many rounds of nuclear division?
zygote.
The cell produced by the fusion of an egg and a sperm is the
germ-line cells.
In animals, the cells that will eventually undergo meiosis to produce gametes are set aside early in development. These are called
prophase I.
Crossing over between homologous chromosomes takes place during
The way one pair of homologues lines up along the metaphase plate does not affect how any other pair lines up.
Which best describes the process of independent assortment?
mitosis
All of the following increase genetic variation EXCEPT
failure of 1 homologous pair to segregate during meiosis.
In 95% of cases of Down's syndrome, there is one extra chromosome (number 21) in every cell. This aneuploid condition is most likely the result of
genes
In modern terminology, Mendel’s heredity “factors” are called
phenotype
The observable expression of the genes present in an organism is called its
alleles
Alternate forms of the same gene are called
3 yellow: 1 green
In Mendel's experiments on seed color in pea plants, when a dominant yellow seed-bearing plant was crossed with a recessive green seed-bearing plant, what was the approximate phenotypic ratio among the F2 generation?
heterozygous
If fertilization involves two gametes that contain different alleles of a given gene, the resulting offspring is
test cross
What type of cross is used to determine if an individual with the dominant form of a trait is homozygous or heterozygous?
purple flowers, tall
Let P = purple flowers and p = white, and T = tall plants and t = dwarf. If the upper case letters represent the dominant alleles, what is the phenotype of a plant with the genotype PpTt?
non-homologous chromosomes segregate independently of each other.
Mendel's Principle of Independent Assortment states that different pairs of
autosomes
Of the 23 pairs of human chromosomes, 22 pairs are homologous and are found in both males and females. These are called ________.
21
In humans, individuals with trisomy of chromosome ______ most likely to survive until adulthood.
for diagnosis of genetic disorders.
Amniocentesis is a procedure that is normally used
be female because each cell lacks a Y chromosome.
In humans, if non-disjunction led to an individual with a genotype of XO, that person would
In humans, the male determines the gender of the offspring, and in birds the female determines the gender.
Male humans have an X and Y sex chromosome, while females have two X chromosomes. In birds, the female has a Z and a W sex chromosome, while the male has two Z chromosomes. Which of the following statements is accurate about which parent determines the gender of the offspring?
1
How many Barr bodies does a normal human female contain in each diploid cell?
double helix
Watson & Crick developed a model of DNA in which the two strands twist into the shape of a ____.
complementary
Because the two strands of a DNA molecule are ________ to each other, either one can be used as a template to reconstruct the other.
semiconservative method.
The method of DNA replication, where each original strand is used as a template to build a new strand, is called the
polymerase
Which enzyme adds new nucleotides to the end of a growing strand?
A = T and G = C
Chargaff's rules for the pairing of nitrogen bases is
discontinuous.
The lagging strand is replicated with a series of Okazaki fragments and that is why its synthesis is considered to be
The newly synthesized DNA is packaged into one nucleus, and the original DNA is packaged into another nucleus.
Which of the following statements about DNA replication is false?
36%
If 14% of the nucleotides from a DNA molecule contain the base T, what percent will contain the base G?
DNA helicase
During replication, which enzyme unwinds the DNA double helix?
using multiple origins of replication on each chromosome.
Eukaryotic organisms speed up the process of DNA replication by
Franklin
Who provided X-ray diffraction photographs of purified DNA fibers that suggested a helical structure with a consistent diameter of about 2 nm and a complete helical turn every 3.4 nm?
purines and pyrimidines
If we think of the DNA double helix as a twisted ladder, what makes up the rungs or steps of the ladder?
proteins
DNA affects the traits of an organism by providing the instructions for synthesizing _______.
transcription
Gene expression involves two phases, ___________ and translation.
promoter
To begin transcription, RNA polymerase must bind to a segment of DNA called the ____.
non-coding
The strand of DNA that is not transcribed is called the ______ strand.
codons
Crick and his colleagues proposed that the genetic code consists of a series of blocks of information, called ______, each corresponding to one amino acid in an encoded protein.
splicing
During transcription of mRNA in eukaryotes, some sequences are cut out of the primary transcript and the remaining sequences are joined together. This processing of mRNA is called _________.
ribosomes
The polypeptide-making organelles, which consist of protein combined with RNA, are called
Inside the nucleus.
In eukaryotic cells, transcription occurs
64
How many unique mRNA codons can be constructed from the four different RNA nucleotides?
release factors.
Codons that serve as "stop" signals for translation are recognized by
peptide
When a polypeptide is being assembled, the bond that forms between a newly added amino acid and the previous amino acid in the chain is a _________ bond.
removal of exons from the pre-mRNA.
In eukaryotes, pre-mRNA processing may involve all of the following except
DNA→ RNA→ proteins.
Which of the following is a correct flow of gene expression?
mRNA
In eukaryotes, the 3' poly-A tail is attached to
homeostasis
The maintenance of a constant environment in a cell is called __________.
stable
Eukaryotic cell mRNA transcripts can remain in the cell for hours because they are
specific transcription factors.
Enhancers are the binding sites for the
structural motifs.
The DNA-binding proteins of almost all regulatory proteins use one of a small set of shapes that enable them to fit into the DNA major groove. These shapes are called
is only rarely available; producing enzymes all the time is costly.
The lac operon regulatory system is important to bacteria primarily because lactose
repressor
A protein that regulates transcription by binding to the operator is known as the