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Exam 1
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What is the therapeutic class for morphine
Opoid analgesic
What is the therapeutic class for hydrocodone
Opoid analgesic
What is the pharmacologic class for morphine
Opoid receptor agonist
What is the pharmacologic class for hydrocodone
mu receptor agonist
What is the MOA for morphine
Binds to mu and kappa receptors to profound analgesia
What is the MOA for hydrocodone
Binds to mu receptor to produce analgesia and sedation
What is the uses of morphine
Moderate to severe acute or chronic pain, CP connected w/ MI, relieve SOB in HF and pulmonary edema
What to monitor when on morphine
Resp. dep., sedation, urinart retent., nausea/vomiting, constipation, assess BP, HR, RR prior and during, may cause orthostatic hypotension
What to monitor when on hydrocodone
Resp. dep., sedation, constipation, assess BP, HR, RR prior and during
AE/Nursing considerations for morphine
Hallucinations, severe resp. dep. or cardiac arrest, administer stool softener
AE/Nursing considerations for hydrocodone
Resp. dep., CNS dep., severe hypotension, hepatotoxicity
What are the side effects for morphine
Nausea, constipation, dizziness, itching, restless, anxiety
What are the contraindications for morphine
Don’t consume alcohol, patients w/ severe asthma, liver or kidney impairment
What are the contraindications for hydrocodone
Patients w/ acute or severe asthma, resp. dep., GI obstruction
What is the antidote for morphine
Naloxone
What is the antidote for hydrocodone
Naloxone
What are the interactions for morphine
Other CNS depressants, St Johns Wort
What are the interactions for hydrocodone
Other CNS depressants, St Johns Wort