CDU Pharm OCHEM LAB - EXP 6

aliphatic hydrocarbon group

General formula of alcohol is ROH where R is a/n?

Water

Alcohols may be looked upon as derivatives of?

insoluble

The longer the carbon chain of alcohol the more _ it is in water

compact or branched

In general, a molecule which is more _ or _ is more soluble in water and have a lower boiling point than straight chain isomers

Phenols

are aromatic alcohols

tert-butyl alcohol

Each sample for this test was soluble. But which sample was the MOST SOLUBLE in water?

Anhydrous

means "taking moisture out"

Blue

(Hydrated) Copper Sulfate or CuSO4 is color?

White

Anhydrous Copper Sulfate or CuSO4 is color?

95% ethanol

What was the hydrating agent used to Test for Water in Alcohol?

Heat it strongly

In Test for Water in Alcohol, if the sample of anhydrous CuSO4 is color blue, we need to?

Bordwell-Wellman Test

Test for oxidation of Alcohols and Phenols is also called?

Potassium Chromate

K2CrO4

What was the reagent used for Bordwell-Wellman test?

Green

Potassium Chromate or K2CrO4 causes what color for alcohols?

1-butanol

yellowish-green

In Bordwell-Wellman test, which sample was the MOST reactive and what was its color?

2-butanol

lighter yellowish-green

In Bordwell-Wellman test, which sample was less reactive than 1-butanol and what was its color??

Tert-butyl alcohol or Tert-butanol

stayed yellow

In Bordwell-Wellman test, which sample was UNreactive?

Aldehyde

Bordwell-Wellman is an Oxidation reaction. When alcohol is oxidized, what is formed?

etOH + CH3COOH

methanol + salicylic acid

Esterification had 2 sub-experiments. Name the samples used.

Sulfuric Acid (H2SO4)

Esterification must be in an acidic medium. What was the acidifying catalyst used?

ethyl acetate (plastic balloon)

methyl salicylate (liniment)

What were the 2 main products of esterification and what were their odors?

a local analgesic and a counterirritant

Methyl salicylate is a _ and a _

Lucas Test

A test for the ability of alcohol to produce an Alkyl Halide (Chloride)

Replacement of OH with Halogen

26-27°C

Lucas Test was subjected in _ °Celsius

HCl + ZnCl2

What is the content of Lucas Reagent?

fast

In Lucas test, how fast was the reaction for tert-butyl alcohol?

moderate

In Lucas test, how fast was the reaction of 2-butanol?

little to no cloudiness

In Lucas test, 1-butanol had _ at endpoint

Cloudiness

What indicates the first sign of reaction in Lucas Test?

tert-butyl chloride [ (CH3)3-C-Cl ]

In Lucas test, tert-butyl alcohol showed immediate reaction. Name the chemical compound produced.

Ferric Chloride (FeCl3) Test

A test for reactivity of chlorides

A test for the presence of aromatic substance

Red to Violet Complex

What is the color of endpoint for Ferric Chloride Test?

Phenol

Which gives the positive endpoint for Ferric Chloride Test: Alcohol or Phenol?

iron-phenolate complexes

What is the product for Ferric Chloride Test?

Phenol

_ had a Red complex at endpoint in FeCl3 test

Salicylic Acid Solution

_ had a Violet complex at endpoint in FeCl3 test

Yellow

1-Butanol stayed _ at endpoint in FeCl3 (no reaction)