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What is this?
osteon

What is this?
Concentric lamella

What is this?
Central canal

What is this?
Perforating Canal

What are these?
Canaliculi

What are these?
Lacuna

What is this?
Circumferential lamella
What is this?
Spongy bone


What is this?
Endosteum

What is this?
Periosteum

What are these?
Sharpey’s fibers
Where are joints?
Any location where joints come together
Where is cartilage found?
In joints, ligaments, and tendons
What is the human skeleton made up of?
Cartilage and fibrous membrane
Where is cartilage found?
Ribs, sternum, in between vertebrae, and in between the pubic symphysis
What type of tissue is cartilage made up of and what is the name?
Connective tissue, specifically, dense, irregular, connective tissue
What does cartilage lack?
Blood vessels and nerves
What are the three main types of cartilage?
Hyaline, elastic, and fibrocartilage
How many cartilages are in hyaline?
Articular, Costal, Respiratory, And nasal
Where is articular cartilage found?
Ends of most bones at movable joints
Where is costal Cartilage found
They connect ribs to sternum
Where is respiratory cartilage found?
They Form skeleton of larynx and reinforce other respiratory passageways
Where is nasal cartilage found?
It supports external nose
Where is elastic cartilage found?
The external ear and epiglottis
Where is fibrocartilage found?
Pad like cartilage of the knee discs between the vertebrae
What is a long bone?
A bone that is longer than it is wide
What is a short bone?
A bone that is roughly cube shaped
What is a flat bone?
A bone that is thin flattened and usually a bit curved
What is a irregular bone?
A bone that has a complicated shape and fits none of the proceeding classes
What are the functions of bone?
To support, Protect, Anchorage, Mineral storage, Blood cell formation, Fat storage, And hormone storage
How do you classify bones?
Based on shape, not on size
Where is compact bone found?
The external surface of all bones
What is a characteristic of spongy bone?
It has little holes called trabeculae, it is lighter, trabeculae Is filled with yellow and red bone marrow
What is an advantage of trabeculae?
It allows for blood vessels and nerves to get through very easily and it is the prime location for bone marrow storage
What is the epiphyseal plate Made up of?
Hyaline cartilage
What is the epiphyseal line Made up of?
Bony tissue

What part of the bone is this?
proximal epiphysis

What part of the bone is this?
Diaphysis

What part of the bone is this?
Distal epiphysis

What is this?
Epiphyseal line

What is this?
Periosteum

What is this?
Compact bone

What is this?
Spongy bone

What is this?
Medullary Cavity

What is this lined by?
Endosteum

What is this?
Yellow bone marrow

What is this?
Endosteum

What is this?
Compact bone

What is this?
Nutrient arteries
What is this?
Periosteum

What Are these?
Sharpey’s fibers
What is an osteoblast?
A bone builder
What is an osteoclast?
Bone crushers
What are osteocytes?
They maintain bone
What is the smallest functional unit of bone?
osteon
What is the blood flow pathway?
Blood vessel to perforating Canal to Central Canal to canaliculi to osteocytes inside lacuna
Why is something organic?
It has lots of carbon and it’s complex
What happens if your bones don’t have minerals?
Your bone bends
What happens if your bone doesn’t have collagen?
Your bone is brittle
Where does intramembraneous classification happen?
Inside the membrane of bones of cranium and clavicles
Where does endochondral classification happen?
Inside cartilage of everything else
What does calcium absorption depend on?
Vitamin D
What builds the mineral portion of the bone matrix?
Calcium
What happens if you have low vitamin D?
You have low calcium, which can give you symptoms of cognitive impairment, Muscle weakness, And osteomalacia
What is vitamin needed for?
For collagen synthesis
What is growth hormone released by?
The anterior pituitary gland
What does growth hormone stimulate?
Stimulates, mitosis and chondrocytes
What does thyroid hormone do for growth hormone?
Modulates growth hormone
What does sex hormones do for growth hormone?
They stimulate the release of growth hormone from pituitary glands, and induce epiphyseal Closure
How are fractures treated?
By reduction
What happens in Bone remodeling?
Hematoma forms, then fibrocartilage forms then Bony callus forms, then bone remodeling occurs
What does it mean if a bone is non-displaced?
The bone didn’t move
What does it mean if a bone is displaced?
The bone moved
At what age do you get the highest bone mass?
30
As you age, what happens to bone?
Bone becomes more brittle, less flexible collagen is made, Osteoblast slow down
Who is more susceptible to the aging in bone?
Woman
What is osteoporosis?
A disease of fragile bones
What does the female hormone estrogen help with?
Lesson or restrain osteoplast activity
What are some treatments for osteoporosis?
Weight-bearing exercise, Vitamin D and calcium supplements, Hormone replacement therapy
What is calcium homeostasis ?
Calcium goes to the parathyroid gland, parathyroid hormone goes up, osteoclast activity goes up, reabsorption of calcium by kidney, absorption of calcium in intestines, then calcium goes up
What happens in endochondral ossification?
First, the bone collar forms around the diathesis, Second cartilage calcifies in the center of the Diaphysis, Third periosteal But invades the internal cavities And spongy bone forms, Fourth the diaphysis elongates and a medullary cavity forms, fifth the epiphyses ossify
What happens in intramembranous ossification ?
First ossification centers developed in the fibrous connective tissue membrane, Second osteoid is secreted and calcifies, Third immature spongy bone and Periosteum form, Fourth compact bone replaces immature spongy bone just deep to the periosteum and and red bone marrow develops
What level is calcium homeostasis?
9-11mg/ 100 ml
What is an open or compound fracture?
When the bone penetrates the skin
What is a closed or simple fracture?
When the bone does not penetrate the skin
What is a complete fracture?
When a bone is broken through
What is an incomplete fracture?
When the bone is not broken through
What are the four stages In repairing a simple fracture
First a hematoma forms, Second fibrocartilaginous callus Forms, Third bony callus forms, And fourth bone remodeling occurs
What is osteomalacia?
When a bone is poorly mineralized often referred to soft bones
What can be caused by insufficient calcium in the diet or by a vitamin D deficiency?
Rickets and osteomalacia
What is rickets?
An analogous disease and children that causes bow legs and deformities of the pelvis, skull and rib cage, because the epiphyseal plates Can’t calcify so they continue to widen and the ends of bones become visibly enlarged and abnormally long
What is pagets Disease?
Excessive and haphazard bone deposit and resorption Usually in the spine pelvis femur and skull