Dr Browns notes

Differentiate

To make or become different in the process of growth or development.

Cytokines

A category of small proteins produced by a wide variety of cells that act as cell signalers.

Glycoproteins

Proteins that have carbohydrate groups attached to the polypeptide chain.

Progenitor cells

Cells that differentiate into another cell type, but only into one specific target cell.

Lymphatic tissues

An organ system that is part of the immune system, including lymphatic vessels, lymph nodes, spleen, thymus, and lymph.

Myeloid

Refers to the tissue of bone marrow and cells that arise from bone marrow.

Lymphoid

Tissue responsible for producing lymphocytes and antibodies.

Hematopoiesis

The development of red blood cells, white blood cells, and platelets.

Hematopoietic stem cells (HSCs)

Stem cells residing in the bone marrow from which blood cells are created.

Common myeloid progenitor (CMP) cells

Progenitor cells that give rise to multiple types of blood cells such as platelets and red blood cells.

Common lymphoid progenitor (CLP) cells

Progenitor cells that differentiate into T cells, B cells, and NK cells.

Colony-stimulating factors (CSFs)

A type of hematopoietic cytokine that stimulates the production of blood cells.

Granulopoiesis

The development of granulocytes from common myeloid progenitor cells.

Thrombopoiesis

The process of platelet production from megakaryocytes.

Endomitosis

A process by which chromosomes duplicate without a subsequent nuclear division, leading to an increase in ploidy.

Apoptosis

Programmed cell death that is highly regulated and controlled.