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Week 4
Neural tube closes, forming brain and spinal cord.
Ectoderm
Neuroectoderm forms nervous tissue.
Lateral horn
Lateral horn contains autonomic preganglionic neurons (T1-L2).
Motor neurons
Basal plate forms motor neuron populations.
Midbrain
Mesencephalon remains midbrain.
Archipallium
Archipallium is the oldest, linked to basic emotions.
Ventricles and subarachnoid space
CSF circulates in ventricles and subarachnoid space.
Pia mater
Pia mater is delicate and vascularized.
Medulla oblongata
Medulla connects brainstem to spinal cord.
40%
Vertebrobasilar system supplies ~40%.
Parietal lobe
Postcentral gyrus in parietal lobe.
Lateral geniculate nucleus
Visual relay in thalamus.
Bitemporal hemianopsia
Loss of peripheral vision both eyes.
Posterior cerebral artery
Visual cortex in occipital lobe.
Amygdala
Amygdala processes fear and emotion.
Left superior temporal gyrus
Language comprehension center.
Damage to somatosensory cortex
Sensory deficits in contralateral body.
Thalamic pain syndrome
Chronic pain after thalamic lesions.
Upper motor neuron lesion
Positive Babinski suggests corticospinal tract damage.
Intermediate hemisphere
Coordinates limb movements.
Spinocerebellar tract
Important for fine motor control.
Tectospinal tract
From superior colliculus.
V, VII, IX, X
Mixed nerves have sensory and motor fibers.
Sympathetic
Sympathetic activates fight-or-flight.
Hypothalamus
Regulates homeostasis.
Lateral horn
Thoracolumbar spinal cord.
Partial vasoconstriction
Maintains vessel tone.
Spinal nerves
Mixed nerves carrying multiple fibers.
Hippocampus
Converts short-term to long-term memory.
Facts and events
Semantic and episodic memory.
Subconscious level
Includes procedural memory.
Left
Language lateralized to left in most people.
Thalamus
Helps regulate movement.
Cognition and emotion
Multiple higher functions.
Limbic system
Integrates emotions with decision-making.
Fornix
Important for autonomic regulation.
Middle cerebral artery
Major supplier of deep brain structures.
Myotatic (stretch) reflex
Maintains posture.
Golgi tendon reflex
Protects tendons from injury.
Muscle stretch
Key for proprioception.
Cerebellar damage
Cerebellar dysfunction leads to hypotonia.
Paleostriatum
Includes globus pallidus.
Somatic system
Primarily balance-related input.
Vestibular nystagmus
Indicative of vestibular dysfunction.
Lateral funiculus
Carry proprioceptive information.
Sensory relay
Relay center for sensory info.
Medial somatosensory cortex
Medial side of postcentral gyrus.
Dilation
Facilitates breathing in stress.
Lateral horn
Lateral horn contains sympathetic preganglionic neurons.
Limbic system
Emotional and visceral input.
Thalamus
Thalamus is not basal ganglia.
Lateral geniculate nucleus
Visual relay in thalamus.
Corticocerebellar tracts
Planning and coordination.
Smaller
Working memory has limited capacity.
Sensory unit
Sensory unit processes emotional info.
Dorsal columns
Dorsal columns carry fine touch, not proprioception.
Spinothalamic tract
Spinothalamic decussates at spinal level.
Superior parietal lobule
Integrates sensory info.
Sympathetic fibers
Controls vasoconstriction.
Inability to recognize sensations
Impaired sensory perception.