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right upper quadrant organs
liver, gallbladder, right kidney, part of the transverse colon
left upper quadrant orgasn
stomach, spleen, left kidney, splenic flexure of colon
right lower quadrant organs
cecum, appendix, ascending colon
left lower quadrant organs
descending colon/ sigmoid colon
epigastric region
stomach, liver, pancreas, transverse colon
hypogastric regioon
bladder, sigmoid colon
epithelial tissue
protection/ covering or secretion/absorption
epithelial membrane
the epi layer + underlying connective tissue
tight junctions
bind cells together to form leak proof sheets
gap junctions
allow comm. between adjacent cells via an open pore
anchoring junctions
prevent cells from being pulled apart to underlying basement membrane
simple epi
single layer of cells anchored to basement membrane
stratified epi
two or more layers, only the deepest layer is anchored
simple squamous
single layer of flat cells (ex; epithelium of lung alveoli permit diffusion of gas)
simple cuboidal
single layer of cube shaped cells, nuceli are centrally located (ex; the epi lining pancreatic ducts)
simple columnar
rectangular, non-ciliated like the lining of the small intestine, nuclei near basal surface, often feature goblet cells
stratified squamous
deep cell layers are cuboidal but closer to apical surface they are squamous
can be keratinized or non-keratinized (ie; skin vs oral cavity)
exocrine gland (glandular epi)
secretes substances intpo ductal system
endocrine gland (glandualr epi)
secrete substances directly into bloodstream
CT
an abundant and widely distributed group of tissues that support, protect, bind, etc
made of three elements (cells, protein fibers, ground substance)
characteristics of CT
several cell types, greater space between cells compared to epi tissue, varying amoutns of ECM, does not occur on free surfaces
examples of connective tissue
bone, blood, adipose tissue, tendons/ligaments, areolar tissue
fibroblasts
“the primary active cell of connective tissue that builds and maintains the structural framework of the body by secreting extracellular matrix proteins like collagen”
located in vascularized tissues
adipocytes
triglycerides stored in a large fat droplet
collagen fibers
synthesized by fibroblasts, long, tensile, most abundant in the body
ground substance
material between cells/ protein fibers
water, proteoglycans, saccharides and proteins, ions
areolar CT
widely distributed in body as it provides structural support, contains all three fibers, type of loose CT
(ie; lamina propria of mucous membranes/ superficial dermis of skin)
adipose tissue
comprised of adipocytes, found within areolar CT, highly vascularized, type of loose CT
reticular CT
contains a network of interwoven reticular fibers
(ie; in lymph nodes )
dense regular CT
bundles of collagen fibers, flattened fibroblasts, able to withstand tensile stress (ligaments and tendons)
dense irregular CT
sheets of closely packed but irregularly arranged collagen fiber bundles, able to withstand pulling forces in many directions, should find collagen/capillaries/nerves but not goblet cells
elastic CT
densely packed, allows stretching and recoil back to original shape
mucous membranes
line the hollow passageways (respiratory, GI tract)
respiratory mucosa
epi layer- cells are anchored to the basement membrane and it has pseudostrat- ciliated columnar epi
Ct layer- lamina propria, support/anchor for the epi layer
serous membranes
parietal layer-adheres to body cavity wall
visceral layer- adheres to organ surface (space between layers is a serous cavity)
epidermis
keratinized stratified squamous epi and has keratinocytes, melanocytes, merkel cells and langerhans cells
keratinocytes
most abundant cells, produce keratin(type of protein)
multiple layers of these keratin filled cells surrounded by lipid secretions prevent water loss and provide protection
melanocytes
found in stratum basale and produce melanin
merkel cells
least numerous, located in the stratum basale, contact specialized flattened sensory nerve endings to detect sensations
langerhans cells
type of macrophage, is in the stratum spinosum, engulfs antigens that invaded the epidermis
stratum basale
deepest layer (single row), contains merkel/melanocytes/basal cells
stratum spinosum
8-10 layers of keratinocytes produced by stem cell division in the basal layer, packed closely and anchored by desmosomes
stratum granulosum
3-5 layers of flattened keratinocytes, cells start to die as synthesis of eratin is complete
stratum lucidum
3-5 layers of dead keratinocytes, cells are now full of large amounts of keratin, found in thickskin
stratum corneum
exposed layer, 15-100 layers(depending on what bodily area) of dead keratinocytes, cells are continously replaced by underlying layer
papillary layer
superficial 1/5 of the dermis, areolar CT, contains meissner corpuscles and capillary loops
reticular layer
deep 4/5 of the dermis, dense irregualr CT meaning more provided support and strength, contains capillary loops/ruffini and pacinian corpuscles/ hair follicles/ sweat glands
order of stratum layers
basale (deepest, single layer)
spinosum (8-10 layers)
granulosum (3-5 layers)
lucideum (3-5 layers)
corneum (exposed, 15-100)