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Infection Control
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Disease
Pathological condition of the body, abnormal condition
Types of symptoms
Objective and subjective
Objective symptoms
Signs, evidence observed by someone other than the patient, ex: swelling
Subjective symptoms
Evidence of a disease as reported by the patient, ex: toothache
Syndrome
An assortment of signs and symptoms grouped together that characterize a disease
Pathology
The study of disease
Etiology
Cause of the disease
Diagnosis
Denoting name of disease
Prognosis
Prediction about the course of the disease
Acute
Sharp, severe, describes immediate symptoms such as high fever and pain or distress
Chronic
Not acute, drawn out, describes a condition present over a long time, often without an endpoint, such as a chronic fatigue and anemia
Remission
Lessening or abating, temporary or permanent cessation of a severe condition, such as a case of sinusitis or some stage of cancer
Epidemic
Among people or widespread, a condition prevalent over a wide population, such as many cases of flu or typhoid in an area
Pandemic
All people involved, a disease that is more widespread than an epidemic, occurring over a large geographical area and populace, sometimes worldwide
Endemic
In people, diseases occurring continuously in the same population or locality
Exogenous
Produced outside, refers to causes outside the body, such as illnesses arising from trauma, radiation, hypothermia, and so on
Endogenous
Arising from within the cell or organism, refers to causes arising from within the body, such as infections, tumors, and congenital or metabolic abnormalities
Congenital
Present from birth, refers to condition inherited from parents, such as cystic fibrosis
Degenerative
Breaking down, refers to conditions resulting from natural aging of the body, such as arthritis
Opportunistic
Taking advantage of, refers to disease or infection occurring when the body resistance is lowered, such as with fungal, bacterial, and viral infections.
Nosocomial
Disease in caregiving, refers to diseases passed on from patient to patient in a health-care setting, such as staphylococcal bacterial infections, MRSA, and others. Has been replaced by the terminology hospital-acquired infections in recent years
Monococci
Single form, oval/round form of bacteria
Diplococci
Paired form, oval/round form of bacteria
Staphylococci
Cluster form, oval/round form of bacteria
Streptococci
Chain form, oval/round form of bacteria
Sarcinae
Group of eight, oval/round form of bacteria
Bacilli
Rod-shaped, if oval in shape, coccobacilli, form of bacteria
Sprilla
Rigid, spiral form of bacteria
Spirochetes
Flexible, spiral form of bacteria
Vibrios
Curved rod, spiral form of bacteria
Bacteria
One-celled, plant-like microorganisms lacking chlorophyll
3 forms of bacteria
oval/rounded, rod-shaped, and spiral
Aerobic
Designated bacteria that require oxygen to live
Facultative aerobes
Bacteria that can live in the presence of oxygen but do not require it
Obligate or strict aerobes
Bacteria that cannot survive without oxygen, such as diphtheria
Anaerobic
Bacteria that do not need oxygen for survival
Facultative anaerobes
Bacteria that grow best without oxygen but can survive in its presence, for example, bacterium fusiform
Obligate or strict anaerobes
Bacteria that cannot live in the presence of oxygen
Flagella
Whips, small, whip-like hairs that provide movement for some bacteria
Spore
Thick-walled reproductive cell, this covering is hard to destroy
Viruses
Tiny parasitic organisms that cause diseases such as polio, hepatitis, colds etc, viruses require living matter to reproduce and grow
Rickettsia
Microbes smaller than bacteria but larger than viruses; usually transmitted by vectors such as fleas or ticks, causes diseases such as Lyme or Rocky Mountain spotted fever
Fungi
A division of plants that include mold, yeasts, and slimes, some fungi are beneficial, and others are pathogenic, the latter of which cause thrush, athlete’s foot, or ringworm
Two forms of fungi
Filamentous (molds) and unicellular (yeasts)
Protozoa
Small animal parasites or organisms, must live upon another organism called the host, protozoan organisms cause malaria, dysentery, and encephalitis, for example
Saprophytes
Organisms living on decaying or dead organic matter, such as tetanus bacillus (lockjaw)
Nematodes
Small parasitic worms such as threadworms and roundworms
Commensal
Living together, microbes that live together on a host without harming it, such as mouth flora
Blood-borne pathogens
Disease-producing microbes that are present in human blood
Droplet infection
Airborne infection in which pathogens discharged from the mouth or nose by coughing or sneezing are carried through the air and settle on objects
Indirect infection
Infection resulting from improper handling of materials, contamination or articles, or fomes, poor sterilization methods permit passage of microbes from one person to another
Contact infection
Infection that is passed directly through intimate relationship-contact with saliva, blood or mucous membranes
Parenteral entry
Refers to piercing of the skin or mucous membrane; also called “needle stick”
Carrier infection
Exchange of diseases by direct or indirect contact with an infected human or animal
Vector-borne infections
An infection that is transmitted by an organism such as a fly or mosquito
Food, soil, or water infection
Infection passed along by microbes present in these media, in the dental office, water lines may harbor a biofilm containing bacterial cells that adhere to moist surfaces and form a protective slime that can carry pathogens or nematodes
Chain of Infection
Causative Agent Pathogens, Reservoir Body Conditions, Port of Exit: cough, urine, feces, blood, Mode of Transmission: droplet, contamination, injection, Port of Entry: droplet, contamination, injection, Susceptible Host: human/animal/plant
Immunity
Resistance to organisms due to previous exposure, may be affected by the virulence of a disease, and classified either natural, artificial, active or passive
Natural Immunity
Inherited and permanent
Natural Acquired Immunity
Obtained when a person is infected by a disease, produced antibodies, and then recovers from that disease
Artificial acquired immunity
Obtained from inoculation or vaccination against a disease
Passive acquired immunity
Results from receiving antibodies from another source, such as breast milk, or from injections of gamma globulin, antitoxins, or immune serums
Passive natural immunity
Passes from mother to fetus, congenitally or through antibodies in breast milk
Immunocompromised
Having a weakened immune system, resulting from drugs, irradiations, disease such as AIDS, or malnutrition
Inoculation
Injection of microorganisms, serum, or toxin into the body
Vaccination
Inoculation with weakened or dead microbes
Antigen
Substance that induces the body to form antibodies
Antibody
Protein substance produced by the body in response to an antigen
Vaccine
Solution of killed or weakened infectious agents injected to produce immunity
Autogenous vaccine
Vaccine produced from a culture, or bacteria taken from the patient who will receive the vaccine
Attenuated
Diluted or reduced virulence of pathogenic microbes
Asepsis
Free from germs
Sanitation
Application of methods to promote a favorable germ-free state
Disinfection
Application of chemicals to kill, reduce, or eliminate germs
Sterilization
The process of destroying all microorganisms
Universal precautions
Assuming all patients are infectious and applying every method of combating disease and infection
Critical
Instruments used to penetrate soft tissue or bone, or enter into the bloodstream such as forceps, scalpels or chisels, steam under pressure, dry heat, or heat/chemical vapor sterilization are suggested
Semi-critical
Instruments that do not penetrate soft tissues or bone but contact the mucous membrane or non-intact skin, high levels disinfection is appropriate if heat/pressure/chemical is not feasible
Noncritical
Instruments that come into contact with intact skin, such as blood pressure cuffs X-ray heads, and so on, EPA-registered “hospital disinfectant” such as phenols and iodophors are acceptable
Sterilization
Total killing of all microbes
Disinfection
Obtaining a germ-free area as much as possible
After use, instruments should ber
Cleaned of debris with enzymatic solutions and then rinsed, dried, packed, and wrapped in cassettes/trays, or prepared as recommended by their manufacturer
Autoclave
Apparatus fore sterilization by steam pressure, temperature (121C, 250F), pressure (15 psi) and time (20 min) are regulated, liquids with lids ajar and linen-wrapped packs require longer exposure, liquids need cooling down and depressurizing periods before removal from units
“Flash” autoclave
Smaller autoclave with higher temperature setting (132C, 270F) will lessen exposure time (3-5 min) required to obtain sterilization
Dry heat sterilization
Oven apparatus used for a hot air bake at high temperature (170C, 340F) for a longer period of time (2 hours), this method is not useful for plastic materials or some paper objects
Molten metal or glass bead heat
Devices holding superheated (234C, 450F) molten metal or small glass beads; used mainly in endodontic practice (no longer recommended by the CDC)
Chemical vapor sterilization
Use of chemicals and heat of 132C or 270C unit for 20 minutes, noncorrosive method that is used on loose or unwrapped articles, particularly metals, proper ventilation and manufacturer’s directions must be followed
Ethylene oxide
Sterilizing unit used at room temperature and required prolonged exposure and devaporization time (10-12 hours), heated units (49C or 120F) require less time (2-3 hours), useful for plastics and materials that do not tolerate heat, not popular in dental office because of size, cost, and toxic devaporing requirements
VPH (vaporized hydrogen peroxide)
Gas plasma sterilization using hydrogen peroxide that is ionized to release vaporized gas molecules capable of killing microorganisms and endospores in a short period ( < 1 hour) with no vapor clear-off time concerns’ compatible with most materials, except liquids, powders, and absorbents, plasma is the fourth stage of matter, because of the size and expense of these machines, they are found in hospital, institutions, and larger dental clinics
Chemical agents
Liquids containing chemicals that kill microbes and spores and require longer immersion time, some chemicals may be disinfectants and/or sterilizers, chemicals classified as sterilants require long (6-10 hours) soaking to kill spores
Indicator strips or commercial spore vials
Placed in or on wrapped items during the sterilization cycle to indicate effectiveness of the sterilizing processj
Two types of indication
Biological and process
Biological indication
Monitoring of sterilization cycle by office spore strips, culture tubes, and vials with encased germs spore indicators that are routinely sent out for laboratory testing to assure that the sterilization process has been achieved
Process indication
Tapes or marked autoclave sleeves indicate that heat conditions have been obtained but do not guarantee that pressure and time have completed the sterilization, the markings on the autoclave bag or sleeve tape change color when exposed to the proper sterilizing conditions, the wrapping or sleeving of the articles provide protection from contamination in handling after sterilization
Cassette Trays
Used to contain instrument setups that travel from operatory use to the ultrasonic cleaning, rinsing, and wrapping for sterilizing and storage until the next use, marked and dated; they may be color-coded to signify which operatory, procedure, operator, or any designation desired for organization
Expensive equipment handling (handpieces, probes, etc)
Should be lubricated and sterilized according to the manufacturer’s directions
Disinfection control
Application of chemicals to kill, reduce, or eliminate germs through soaking, spraying foams, sponges, or wipes
Disinfectant
Chemical or agent that kills many microbes, choice of type, concentration and use is necessary for each item
Antiseptic
Usually, a diluted disinfectant that prevents the growth or inhibits the development of microbes
Bacteriostatic
Inhibiting or retarding bacterial growth