lecture 26 Genetics Applications: Pedigree Analysis, PCR, and DNA Profiling

Flashcards on pedigree analysis, PCR, and DNA profiling

Mary Claire King

A scientist that led a research group that was able to use linkage analysis to identify the gene for early onset familial breast cancer now known as BRCA1.

Pedigree Analysis

A method used to analyze inheritance in existing families since breeding experiments cannot be done on humans.

Recessive Inheritance

Pattern of inheritance where affected children have unaffected parents.

Dominant Inheritance

Pattern of inheritance where an unaffected child has affected parents.

Autosomal

Genes located on chromosomes other than the sex chromosomes

Autosomal Recessive

The inheritance pattern shown in a pedigree where affected children have unaffected parents and males and females are equally affected.

Autosomal Dominant

The inheritance pattern shown in a pedigree where unaffected children have affected parents and both genders are affected.

Dominant Disorders

An inheritance pattern where the trait appears in every generation.

X-linked Recessive

An inheritance pattern where only males are affected.

Polydactyly

Having multiple fingers