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Menstrual Phase (day 1-5)
FSH causes the primordial follicles to develop → primary + secondary follicles which granulosa cells secrete follicular fluid that’s accumulated in antrum + producing estrogen + inhibin
Preovulatory phase (day 6-13)
Secondary follicles mature → tertiary mature ovarian follicles ready for ovulation + granulosa cells ↑ estrogen secretion
Ovulation (day 14)
Rupture of the mature follicle with the release of the secondary oocyte into the pelvic cavity
Postovulatory Phase (day 15-28)
Follicular phase
Menstrual phase
Proliferative phase
Luteal phase
Secretory phase
Estrogen
Made in the ovary → acts on the endometrium → thickens it and helps regulate follicle development.
Progesterone
Made in ovary → acts on endometrium + mammary gands
Endometrium (progesterone)
Progesterone prepares it for implantation
Mammary glands
Progesterone prepares it for milk secretion
Follicle stimulating hormone
Made in anterior pituitary → acts on ovaries in females and testes in males
Female ovaries (FSH)
stimulates initial development of ovarian follicles and secretion of estrogens by the follicles
Male testes (FSH)
Stimulates the Sertoli cells in the testes for spermatogenesis
Luteinizing hormone
Made in anterior pituitary → acts on ovaries in females and testes in males
Female ovaries in (LH)
Causes several primordial follicles to mature into primary follicles
Male testes (LH)
stimulates leydig cells in testes to increase BL of testosterone
Trophoblast
Outer covering, deveops into chorion
Embryoblast/inner cell mass
Inner cell mass, develops into embryo
Umbilical vesicle (yolk sac)
provides the embryo with nutrients during the second and third weeks of development
Amnion
surrounds the embryo, covers the fetal portion of the placenta and the umbilical cord
Amniotic fluid
Absorbs shock and regulates body temp
Stage of dilation
Regular contractions of the uterus, rupture of amniotic sac, complete dilation of cervix
Stage of expulsion
Complete cervical dilation to delivery of baby, which moves through the birth canal
Placental stage
Uterine contractions expel placenta after birth
Estrogens + Progesterone
Made in corpus luteum → acts on uterus and mammary glands
Uterus (estrogen + progesterone)
Progesterone inhibits uterine contractions and rise in estrogens overcomes this inhibition
Mammary glands (estrogen + progesterone)
progesterone inhibits the effects of prolactin until delivery
Relaxin
made from corpus luteum → acts on pubic symphysis + cervix, increases the flexibility of the pubic symphysis + helps dilate the cervix of the uterus to ease delivery
Human Chorionic gonadotropin
Made in chorion of placenta → acts on corpus luteum → to maintain corpus luteum activity, especially continuous progesterone secretion
Oxytocin
made in hypothalamus → acts on mammary glands → causes the contraction of the myoepithelial cells surrounding the acini and ducts the mammary gands,m producing milk ejection to assist infant feeding
Prolactin
Made in anterior pituitary → acts on mammary glands → stimulate the secretory cells of the mammry glands to produce milk
What does LH surge indicate
the most fertile period in ovarian cycle
What is hCG?
Appears in urine and serum of pregnant women, 1st week of pregnancy + produced by pacenta trophoblastic cells
What is the importance of colosstrum
Serves as a placeholder for true breast milk
Fertilization
the union of hte genetic material from a sperm and ovum
Implantation
The attachment of the blastocyst to the endometrium typically occurs 6-8 days following fertilization
Gestation
The time that the embryo or fetus is carried in the uterus
Paturition
The process of giving birth