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Prokaryote
A unicellular organism that lacks a nucleus and membrane bound organelles
Eukaryote
A cell that contains a nucleus and membrane bound organelles
Prokaryotes vs. Eukaryotes
one has a plasma membrane, DNA molecule, ribosomes, cytoplasm, and cell wall; the other includes all organisms except for bacteria, cyanobacteria, and archaebacteria; no nucleus vs nucleus
Human Microbiome Project (HMP)
(2008) A project of the National Institutes of Health to identify microbial inhabitants of the human body and their role in health and disease; uses metagenomic techniques instead of culturing.
gut microbiome
the bacteria and other organisms that live inside our gastrointestinal tract
functions of the gut microbiome
●integral to host digestion and nutrition
●generates nutrients from substrates that are otherwise indigestible by the host
●plays a vital role in synthesizing vitamins B and K
●can produce a range of neuroactive molecules
Gut-Brain Axis
One influences neurotransmitters, stress/anxiety, mood, and behavior; the other influences motility, secretion, nutrient delivery, and microbial balance
skin microbiome
(harmless) microorganisms that live on the surface of human skin and make up the normal skin flora
Functions of the skin microbiome
●Acts as a physical barrier to pathogens while providing a home to
resident microbiota
●protects against the entry of pathogens that cause disease by limiting the nutrients and space
available for pathogenic microbes
●Increases the acidity of the skin making it even more inhospitable to many pathogens
disbyosis
disruption of microbiota; can cause multiple cognitive conditions
Why animals need to eat
activity (e.g. generate ATP)
nutrients (e.g. amino acids,
vitamins, and minerals)
What animals need to eat
●enough calories to fuel activity and includes adequate
levels of essential nutrients.
● Water, carbohydrates, proteins, lipids are
needed in large quantities
● Vitamins and minerals are required in
small amounts
Carbohydrates
Sugars and starches in fruits, vegetables, cereals and other grains
Lipids
Oil, margarine, salad dressings, meat, fish, poultry, nuts, fried foods, dairy products made with whole milk
Proteins
Meat, fish, poultry, eggs, nuts, dried beans and peas, soybeans, cereal products, milk, cheese, yogurt
Minerals
Widespread in veggies and other foods
Vitamins
Widespread in foods; plant foods are a good source of antioxidants
Water
Widespread in foods, beverages
Primary Physiological Roles of Carbohydrates
Glucose is metabolized for energy; fiber adds to fecal bulk, preventing constipation
Primary Physiological Roles for Lipids
Tryglicerides are metabolized for energy and stored for insulation and protection of organs. Cholesterol is used to make certain hormones, bile, and vitamin D.
Primary Physiological Roles for Proteins
Proteins are needed for building, repairing, and maintaining tissues; synthesizing enzymes and certain hormones; and producing antibodies
Primary Physiological Roles for Minerals
Regulation of energy metabolism, maintenance of fluid balance, and production of certain structures, enzymes, and hormones
Primary Physiological Roles for Vitamins
Regulation of metabolism and physiological development
Primary Physiological Roles for Water
Participant in many chemical reactions; needed for maintenance of body fluids, temperature regulation, joint lubrication, and transportation of material in cells and the body
Carbohydrates are ___
macronutrients
Lipids are _
macronutrients
Proteins are __
macronutrients
Minerals are _
micronutrients
Vitamins are _
micronutrients
Is water a micronutrient or a macronutrient?
Neither!
Considered "fuel"
Carbohydrates, Lipids, and Protein
Considered to be "nutrients"
Lipids, proteins, minerals, and vitamins
and _ are both considered fuel and nutrients
Lipids and Proteins
Macronutrients vs. Micronutrients
One constitutes the majority of an individual's diet; the other consists of vitamins and trace minerals.
Simple sugars (monosaccharides)
building blocks of carbohydrates; glucose, fructose, galactose
Dissacharides
A sugar containing two monosaccharides. Ex: sucrose which is fructose + glucose; sucrose, lactose, maltose
complex carbohydrates (polysaccharides)
compounds comprised of 10 or more monosaccharides bonded together; starch, glycogen, fiber
Saturated fat
A lipid made from fatty acids that have no double bonds between carbon atoms; solid at room temperature
Unsaturated fats
A fat that is liquid at room temperature and found in vegetable oils, nuts, and seeds.
Trans fat
An unsaturated fat, formed artificially during hydrogenation of oils, containing one or more trans double bonds.
essential amino acids
Amino acids that are needed, but cannot be made by the body; they must be eatin in foods; includes histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, valine
How essential amino acids are related to a "complete" protein
Vitamins are
organic molecules that are required in small amounts and cannot be synthesized by the body
Vitamins _
have a variety of functions, but many act as coenzymes/cofactors (accessory molecules required by enzymes to function)
Components of a Healthy Diet
adequate, moderate, balanced, varied;
●Fats, oils, and sweets (sparingly)
●Milk, yogurt, and cheese groups (2-3 servings)
●Meat, Poultry, Fish, Dry Beans, Eggs, and Nuts Group (2-3 servings)
●Fruit Group (2-4 servings)
●Veggie Group (3-5 servings)
●Bread, Cereal, Rice, and Pasta Group (6-11 servings)
unprocessed food
which have not been treated with chemicals that preserve them or give them extra taste or colour
processed food
foods that have been treated to change their physical, chemical, microbiological, or sensory properties; commercially prepared food bought for convenience
Ultraprocessed foods
Cheap, ready to consume, high in fat and sugar, and low in fiber
Obesity
having an excess amount of body fat; quality of being excessively overweight
BMI (body mass index)
a person's weight in kilograms divided by the square of height in meters, a measure of body weight relative to height; used to measure obesity
obesity health risks
premature death
• type 2 diabetes
• heart disease
• stroke
• hypertension
• gallbladder disease
• osteoarthritis (degeneration of cartilage and bone in joints)
• sleep apnea
• asthma.
• breathing problems
• cancer (endometrial, colon, kidney, gallbladder, and postmenopausal breast cancer)
• high blood cholesterol
• complications of pregnancy
• menstrual irregulanties
and facial hair)
caused by weak pelvic-floor muscles)
• increased surgical risk
depression
social stigmatization
• hirsutism (presence of excess body
• stress incontinence (urine leakage
• psychological disorders such as
• psychological difficulties due to social stigmatization
Negative feedback loops
Stimulus is sensed by a sensor, processed, and the effect acts to reduce the thing causing the stimulus.
_ can be used to keep things in a state of homeostasis (like a constant temperature in your apartment)
Negative feedback loops
Diabetes
Otherwise known as Diabetes mellitus; is defined as a condition characterized by prolonged hyperglycemia [elevated blood glucose levels] resulting from the body's inability to regulate blood sugar
Type I Diabetes
(10%) - body does not produce insulin