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Unit 3
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What does continuinity of life require?
The replication of genetic material and its transfer to the next generation through processes, including binary fission, mitosis, meiosis and fertilisation
Why do cells need to divide?
For growth and repairment of damaged body cells
What is Binary fission
A process of asexual reproduction where a prokaryotic cell divides into 2 identical daughter cells
The DNA segregates and the cell divides all in one step and relatively faster
What is meiosis?
A type of cell division that produces gametes (sperm and egg cells) with half the number of chromosomes as the original cell.
This ensures that when fertilisation occurs, the offspring has the correct number of chromosomes
What are the steps of phase 2 in meiosis?
Prophase II:
Chromosomes condense again in born cells
Spindle fibres form
Metaphase II:
Chromosomes line up at the centre of the cell
Anaphase II:
Sister chromatids (identical halves of a chromosome) are pulled apart to opposite sides
Telophase II & Cytokinesis:
4 haploid cells form, each genetically unique
What are the steps of phase I of meiosis?
Prophase 1:
Chromosomes condense and become visible
Homologous chromosomes (matching pairs) pair up
Crossing over: sections of DNA are exchanged between homologous chromosomes, increasing genetic diversity
Metaphase 1:
Homologous chromosome pairs line up in the middle of the cell
Independent assortment: chromosomes are randomly arranged, leading to variation
Anaphase 1:
Homologous chromosomes are pulled apart to opposite ends of the cell
Telophase 1 & Cytokinesis:
2 new cells form, each with half the original chromosome number (haploid)
Nuclear membranes may reform temporarily
Why is meiosis important?
Genetic variation: creates variation through crossing over and independent assortment
Maintains chromosome number: halves chromosome number in gametes so when fertilisation occurs the normal number is restored
Essential for sexual reproduction: without meiosis, offspring would have double the chromosomes with each generation
Draw the steps of meiosis
diagram
what are the sources of genetic variation in meiosis?
Crossing over (prophase I): exchange of DNA between homologous chromosomes
Independent assortment (metaphase I): random arrangement of chromosomes leads to different combinations of gametes
Random fertilisation: any sperm can fertilise any egg, leading to even more variation
What is the difference between haploid and diploid?
Haploid (n): a cell with the half the normal chromosome number, e.g. gamete
Diploid (2n): a cell with a full set of chromosomes, e.g. a body cell
What is mitosis?
Type of nuclear division in somatic cells that maintains the parental diploid number of chromosomes in the daughter cells
Forming two identical daughter cells
Make a comparison table between mitosis and meiosis
make one in onenote and copy photo here
What are the stages of mitosis?
Prophase:
Chromatin threads condense to form chromosomes (two sister chromatids held together by centromere)
Nuclear membrane disintegrates and nucleolus disappears
Spindle begins to form, fibres attach to each chromosome at its centromere
The two centrosomes move towards opposite poles of the cell
Metaphase:
The chromosomes move to the centre of the cell and line up along the equator
Centromeres of chromosomes are aligned on the equator
Centrioles are located at opposite poles of the cell
Spindle fibres attach to the centromere
Anaphase:
Sister chromatids separate
Sister chromatids are pulled to opposite part of the cell
Each pole has complete identical set of maternal and paternal chromosomes
Sister chromatids are now chromosomes
Telophase
Chromosomes decondense (forms chromatin)
Two new nuclear envelopes form (one for each new daughter cell)
Spindle disappears
Cell elongates and is ready for cytokinesis to separate.