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What is happening mechanically during the P wave, QRS complex, and T wave?
P wave
Atrial depolarisation
Electrical signal spreads through the atria
Atria contract (squeeze)
Blood moves into the ventricles
QRS complex
Ventricular depolarisation
Ventricles receive the electrical signal
Ventricles contract strongly
Blood is pumped out of the heart
T wave
Ventricular repolarisation
Ventricles recover / reset electrically
Prepares for the next heartbeat
What are the key components of a respiratory assessment?
Respiratory rate
Work of breathing (use of accessory muscles)
Oxygen saturation (SpO₂)
Breath sounds
Skin colour (cyanosis)
Ability to speak full sentences
Level of consciousness
🫀 Simple understanding
You are checking:
“Is the patient getting enough oxygen and working too hard to breathe?”
⚠ Red flags
RR >20 or low
Low SpO₂
Confusion (early hypoxia sign)
What is acute myocardial ischaemia?
Reduced blood flow to heart muscle
Usually due to blocked coronary artery
Causes chest pain and heart muscle damage if
🫀 Simple understanding
Heart muscle is starving of oxygen because blood supply is blocked.
⚠ Red flags
Crushing chest pain
Pain radiating to arm/jaw
Sweating, nausea
Abnormal ECG changes
Raised troponin
What is a stroke?
Interruption of blood flow to the brain
Either blockage (ischaemic) or bleeding (haemorrhagic)
Causes sudden neurological deficits
🫀 Simple understanding
Part of the brain is not getting oxygen → brain cells start dying quickly.
⚠ Red flags (FAST)
Face droop
Arm weakness
Speech difficulty
Time critical emergency
What is sepsis?
Life-threatening response to infection
Causes organ dysfunction
Medical emergency
🫀 Simple understanding
Body overreacts to infection → damages its own organs.
⚠ Red flags
Fever or hypothermia
Fast heart rate
Fast breathing
Confusion
Low blood pressure
What is pneumonia?
Infection of lung tissue (alveoli)
Causes fluid/pus in lungs
Reduces oxygen exchange
🫀 Simple understanding
Lungs are filled with fluid so oxygen can’t get in properly.
⚠ Red flags
Fever
Cough with sputum
Low oxygen
Crackles on auscultation
What is hypoxia?
Low oxygen supply to body tissues
Can occur even if oxygen is being given
🫀 Simple understanding
The body is not getting enough oxygen where it matters (organs/tissues).
⚠ Red flags
Confusion (early sign)
Cyanosis (late sign)
Restlessness
Low SpO₂
What is a pulmonary embolism?
Blockage in pulmonary artery
Usually a blood clot from legs (DVT)
Stops blood flow to lungs
🫀 Simple understanding
A clot travels to the lungs and blocks blood flow → oxygen can’t get into blood properly.
⚠ Red flags
Sudden shortness of breath
Chest pain (sharp, worse on breathing)
Tachycardia
Low oxygen
Possible collapse
What are signs of respiratory distress?
Increased respiratory rate
Use of accessory muscles
Difficulty speaking
Low oxygen saturation
Anxiety/restlessness
🫀 Simple understanding
The patient is working too hard to breathe.
⚠ Red flags
Silent chest (very serious)
Exhaustion
Falling RR after being high (fatigue sign)
What happens in an asthma attack?
Airways narrow due to inflammation and bronchospasm
Air gets trapped in lungs
Breathing becomes difficult
🫀 Simple understanding
Airways tighten like a squeezed tube → air can’t move properly.
⚠ Red flags
Wheeze or silent chest
Difficulty speaking
Low SpO₂
Poor response to inhalers
What is a COPD exacerbation?
Sudden worsening of chronic lung disease
Increased breathlessness and sputum
Often triggered by infection
🫀 Simple understanding
Long-term damaged lungs suddenly get worse (often infection-related).
⚠ Red flags
Increased CO₂ retention
Drowsiness (CO₂ narcosis)
Low oxygen
Increased sputum/purulence
What is a pneumothorax?
Air in pleural space
Lung collapses partially or fully
Stops normal breathing on affected side
🫀 Simple understanding
Air leaks outside the lung → lung can’t stay expanded.
⚠ Red flags
Sudden chest pain
Sudden breathlessness
Reduced breath sounds on one side
Tracheal deviation (tension pneumothorax = emergency)
What is respiratory failure?
Inability of lungs to maintain oxygen or remove CO₂
Can be acute or chronic
🫀 Simple understanding
Lungs are failing at gas exchange.
⚠ Red flags
Very low SpO₂
Rising CO₂
Confusion/drowsiness
Exhaustion
What is Acute Coronary Syndrome (ACS)?
Umbrella term for reduced blood flow to the heart
Includes: unstable angina, NSTEMI, STEMI
Caused by coronary artery blockage
🫀 Simple understanding
Part of the heart is not getting enough oxygen because a coronary artery is narrowed or blocked.
⚠ Red flags
Chest pain (crushing, central)
Radiates to arm/jaw/back
Sweating, nausea
Shortness of breath
ECG changes + raised troponin (MI)
What is a myocardial infarction?
Death of heart muscle due to lack of oxygen
Usually caused by blocked coronary artery
🫀 Simple understanding
Part of the heart muscle is dying because blood flow is blocked.
⚠ Red flags
Persistent chest pain (>20 min)
Raised troponin
ECG changes (ST elevation in STEMI)
Diaphoresis (sweating), collapse risk
🩺 Nursing actions (UK focus)
MONA principles (often used in teaching):
Morphine (pain)
Oxygen (if hypoxic)
Nitrates
Aspirin
Continuous ECG monitoring
Prepare for PCI (angioplasty)
What is angina?
Chest pain caused by temporary reduced blood flow to heart
No permanent heart muscle damage
🫀 Simple understanding
Heart is temporarily “short of oxygen” during exertion or stress.
⚠ Red flags
Pain triggered by exertion
Relieved by rest or GTN spray
If NOT relieved → may be MI
What is heart failure?
Heart cannot pump blood effectively
Leads to fluid build-up and poor circulation
🫀 Simple understanding
The heart is too weak to pump properly → fluid backs up into lungs/body.
⚠ Red flags
Breathlessness (especially lying flat)
Swollen legs (oedema)
Fatigue
Crackles in lungs
Weight gain (fluid retention)
🩺 Nursing focus
Fluid balance monitoring
Daily weights
Diuretics (e.g., furosemide)
Oxygen if needed
What is cardiac arrest?
Sudden stop in effective heart function
No circulation or pulse
Medical emergency
🫀 Simple understanding
The heart stops pumping blood → organs stop receiving oxygen.
⚠ Red flags
Unresponsive
Not breathing normally
No pulse
🩺 Nursing action (UK resus)
Call emergency response
Start CPR immediately
Defibrillation (AED) ASAP
Follow ALS guidelines
What is an arrhythmia?
Abnormal heart rhythm
Can be too fast, too slow, or irregular
🫀 Simple understanding
The heart’s electrical system is not working in a normal pattern.
⚠ Red flags
Dizziness
Chest pain
Palpitations
Collapse risk
What is atrial fibrillation?
Irregular, rapid atrial activity
Poor atrial contraction
Blood stasis increases clot risk
🫀 Simple understanding
Atria “quiver” instead of squeezing properly → irregular heartbeat.
⚠ Red flags
Irregular pulse (“irregularly irregular”)
Stroke risk
Fatigue, breathlessness
🩺 Nursing focus
Rate control (e.g., beta blockers)
Anticoagulation (warfarin/DOACs)
Stroke prevention
What is a TIA?
Temporary interruption of brain blood flow
Symptoms resolve within 24 hours
🫀 Simple understanding
“Mini stroke” warning sign.
⚠ Red flags
Stroke symptoms that resolve
High risk of future stroke
What is a seizure?
Sudden abnormal electrical activity in the brain
Causes involuntary movements or loss of consciousness
🫀 Simple understanding
Brain “electrical overload” causing uncontrolled activity.
⚠ Red flags
Loss of consciousness
Jerking movements
Post-ictal confusion (after seizure)
🩺 Nursing actions
Protect airway
Time seizure
Protect from injury
Do NOT restrain patient
What is meningitis?
Infection of meninges (brain coverings)
Can be bacterial (life-threatening) or viral
🫀 Simple understanding
Infection around the brain → inflammation and pressure.
⚠ Red flags
Fever
Neck stiffness
Photophobia
Rash (non-blanching in bacterial meningitis)
Altered consciousness
🩺 Nursing actions
Emergency antibiotics (bacterial)
Isolation if suspected infectious
Rapid escalation
What is raised intracranial pressure?
Increased pressure inside the skull
Can damage brain tissue
🫀 Simple understanding
Brain is swelling or something is taking up space inside skull.
⚠ Red flags
Headache
Vomiting
Reduced consciousness
Unequal pupils
Cushing’s triad (late sign)
What is diabetes mellitus?
Disorder of blood glucose regulation
Either lack of insulin (Type 1) or insulin resistance (Type 2)
🫀 Simple understanding
Body cannot control blood sugar properly.
⚠ Key issues
Hyperglycaemia
Hypoglycaemia risk (especially with insulin)
Long-term organ damage
What is hypoglycaemia?
Low blood glucose (<4 mmol/L)
Can be life-threatening
🫀 Simple understanding
Not enough sugar in blood → brain cannot function properly.
⚠ Red flags
Sweating
Shaking
Confusion
Irritability
Seizures (severe)
🩺 Nursing actions
Give fast-acting glucose (if conscious)
IV glucose if unconscious
Recheck blood glucose
What is hyperglycaemia?
High blood glucose levels
Can lead to DKA or HHS
🫀 Simple understanding
Too much sugar in blood → dehydration and metabolic imbalance.
⚠ Red flags
Thirst
Frequent urination
Fatigue
Confusion (severe cases)
What is Diabetic ketoacidosis DKA?
Severe insulin deficiency
Body breaks down fat → ketones build up
Causes acidosis
🫀 Simple understanding
No insulin → body burns fat → toxic acids build up.
⚠ Red flags
Fruity breath
Deep rapid breathing (Kussmaul respirations)
Abdominal pain
Vomiting
Dehydration
🩺 Nursing actions
IV insulin
IV fluids
Electrolyte monitoring
What is hyperosmolar hyperglycaemic state (HHS)?
Severe hyperglycaemia (usually Type 2 diabetes)
Extreme dehydration
No significant ketones
🫀 Simple understanding
Very high sugar → blood becomes very thick → severe dehydration.
⚠ Red flags
Extreme thirst
Confusion
Very high glucose levels
Dehydration
What is frailty in older adults?
Reduced physiological reserve
Increased vulnerability to illness, falls, and stress
Slower recovery from illness
🫀 Simple understanding
The body has less “backup capacity,” so small illnesses can cause big problems.
⚠ Key nursing risks
Falls
Delirium
Polypharmacy (too many meds)
Dehydration
Pressure ulcers
🩺 Nursing focus (UK)
Falls risk assessment
Hydration monitoring
Skin integrity checks
Medication review
Mobility support
What is delirium?
Acute confusion due to illness
Fluctuating mental state
Often reversible
🫀 Simple understanding
Sudden brain “malfunction” usually triggered by infection, meds, or dehydration.
⚠ Red flags
Sudden confusion
Reduced awareness
Fluctuating attention
Agitation or drowsiness
What increases fall risk in older adults?
Frailty
Poor balance
Medications (sedatives, antihypertensives)
Low blood pressure
Vision problems
🫀 Simple understanding
Body stability + reflexes are weaker, so small imbalance causes falls.
⚠ Nursing actions
Bed low, call bell within reach
Non-slip footwear
Regular toileting
Review medications
What is palliative care?
Care for patients with life-limiting illness
Focus on comfort, dignity, and symptom control
Not focused on cure
🫀 Simple understanding
Not trying to cure — trying to make the patient as comfortable as possible.
⚠ Key priorities
Pain control
Breathlessness management
Anxiety relief
Emotional + family support
🩺 Nursing focus
Symptom control (opioids, antiemetics)
Holistic care
Communication + dignity
What are the “rights” of medication administration?
Right patient
Right drug
Right dose
Right route
Right time
🫀 Simple understanding
Always make sure the correct drug is given safely to the correct person at the correct time.
⚠ safety priorities
Allergy checks
Double checking high-risk meds
Documentation immediately
Avoid interruptions during meds round
🚨 High-risk meds (important)
Insulin
Anticoagulants (e.g. warfarin)
Opioids
IV potassium
What does the kidney do?
Filters blood
Removes waste and excess fluid
Controls electrolytes
Regulates blood pressure
🫀 Simple understanding
Kidneys are the body’s “filter system.”
⚠ When kidneys fail
Fluid overload
Electrolyte imbalance
Toxin build-up
Reduced urine output
What is AKI?
Sudden loss of kidney function
Often reversible if treated early
🫀 Simple understanding
Kidneys suddenly stop filtering properly.
⚠ Causes
Dehydration
Sepsis
Medications (NSAIDs)
Low blood pressure
🩺 Nursing focus
Monitor urine output
Fluid balance charts
Check creatinine/urea
Stop nephrotoxic drugs
What is CKD?
Long-term, progressive kidney damage
Irreversible decline in function
🫀 Simple understanding
Kidneys slowly lose function over time.
⚠ Signs
Fatigue
Fluid retention
Itching
Anaemia
🩺 Nursing focus
Blood pressure control
Diet/fluid management
Dialysis preparation if advanced
Why is sepsis dangerous?
It reduces blood flow to organs
Causes low oxygen delivery
Leads to organ failure
🫀 Simple understanding
Organs start shutting down because they are not getting enough oxygen and blood.
What are early signs of sepsis?
Fever or low temperature
Fast heart rate (tachycardia)
Fast breathing (tachypnoea)
Confusion or reduced alertness
Feeling very unwell
🫀 Simple understanding
The body is “panicking” trying to fight infection.
What are late signs of sepsis?
Low blood pressure
Reduced urine output
Cold, mottled skin
Severe confusion or unconsciousness
🫀 Simple understanding
The body is now failing to maintain circulation.
What is a deteriorating patient?
A patient whose condition is worsening over time
Often shown by abnormal vital signs
🫀 Simple understanding
The body is moving from “coping” → “failing”
What is NEWS2 used for?
National Early Warning Score system
Detects patient deterioration
Uses vital signs to trigger escalation
🫀 Simple understanding
A scoring system that tells nurses when a patient is getting worse.
⚠ What it looks at
Respiratory rate
Oxygen saturation
Blood pressure
Pulse
Temperature
Consciousness level
Why is early recognition of sepsis important?
Early treatment improves survival
Delayed treatment increases organ failure risk
🫀 Simple understanding
The earlier you act, the more reversible it is.
What is Sepsis 6?
Six urgent interventions:
Oxygen
Blood cultures
IV antibiotics
IV fluids
Lactate measurement
Urine output monitoring
🫀 Simple understanding
A fast treatment bundle to stop sepsis progressing.
What is anaphylaxis?
Severe, life-threatening allergic reaction
Causes airway, breathing, and circulation problems
Rapid onset
🫀 Simple understanding
The body overreacts massively to an allergen and starts shutting down breathing and circulation.
What can trigger anaphylaxis?
Food (nuts, shellfish)
Medications (antibiotics, NSAIDs)
Insect stings
Latex
🫀 Simple understanding
Something harmless triggers an extreme immune reaction.
What happens physiologically in anaphylaxis?
Airway swelling (laryngeal oedema)
Bronchoconstriction
Blood vessels dilate → low blood pressure
Fluid leaks into tissues
🫀 Simple understanding
Airways tighten, face/throat can swell, and blood pressure drops.
What are the signs of anaphylaxis?
Difficulty breathing / wheeze
Swollen face, lips, tongue
Rash or hives
Low blood pressure
Dizziness or collapse
🫀 Simple understanding
Breathing becomes hard AND circulation starts failing.
Why is anaphylaxis life-threatening?
Airway can close
Blood pressure can drop
Can lead to cardiac arrest
🫀 Simple understanding
The patient can suffocate and collapse within minutes.
What is the first-line treatment for anaphylaxis?
Intramuscular adrenaline (epinephrine)
🫀 Simple understanding
Adrenaline reverses swelling, opens airways, and raises blood pressure.
What else is given in anaphylaxis management?
Oxygen
IV fluids
Antihistamines
Steroids (supportive, not immediate lifesaving)
🫀 Simple understanding
Support breathing, circulation, and reduce allergic response.
What should a nurse do in suspected anaphylaxis?
Call emergency help immediately
Give IM adrenaline
Lay patient flat (raise legs if possible)
Give oxygen
Monitor vital signs
🫀 Simple understanding
Act fast — don’t wait for it to “confirm itself.”
What is hypovolaemic shock?
Shock caused by low blood volume
Due to fluid or blood loss
🫀 Simple understanding
Not enough “fluid in the system” to circulate blood properly.
⚠ Causes
Bleeding (trauma, surgery)
Severe dehydration
Vomiting/diarrhoea
🚨 Signs
Fast heart rate
Low blood pressure
Cold, clammy skin
Low urine output
What is cardiogenic shock?
Heart fails to pump effectively
Leads to poor circulation
🫀 Simple understanding
The pump is weak, so blood can’t move around the body.
⚠ Causes
Myocardial infarction (heart attack)
Severe heart failure
Arrhythmias
🚨 Signs
Low blood pressure
Pulmonary oedema (fluid in lungs)
Breathlessness
Cold, clammy skin
What is septic shock?
Severe infection causing dangerous drop in blood pressure
Body-wide inflammation leads to organ failure
🫀 Simple understanding
Infection causes blood vessels to widen and leak → circulation collapses.
⚠ Causes
Severe sepsis
Pneumonia
UTI
Abdominal infections
🚨 Signs
Fever or low temp
Very low blood pressure
Confusion
Fast heart rate
High lactate
What is anaphylactic shock?
Severe allergic reaction causing circulatory collapse
Blood vessels widen + leak
🫀 Simple understanding
Massive allergic reaction → blood pressure crashes + airways tighten.
🚨 Signs
Swelling (face, throat)
Wheeze
Rash
Severe hypotension
Collapse
What are the different shocks?
organs not getting enough oxygen
But the causes differ:
💧 Hypovolaemic = not enough fluid
❤ Cardiogenic = pump failure
🧪 Septic = infection causes vasodilation + leak
⚠ Anaphylactic = allergic vasodilation + airway swelling
🧩 SIMPLE MEMORY TRICK
Think:
💧 “Empty tank” = hypovolaemic
❤ “Weak pump” = cardiogenic
🧪 “Infected system” = septic
⚠ “Allergic explosion” = anaphylac
What is a UTI?
Infection of urinary system (usually bladder)
Caused by bacteria (often E. coli)
🫀 Simple understanding
Bacteria enter the urinary tract → causes irritation and infection.
⚠ Signs
Burning when urinating
Frequent urination
Confusion in older adults
Fever (if severe)
What is C. difficile infection?
Bacterial infection of the bowel
Often after antibiotic use
🫀 Simple understanding
Gut bacteria is disrupted → harmful bacteria take over → severe diarrhoea.
⚠ Signs
Severe watery diarrhoea
Abdominal pain
Fever
Dehydration
What is MRSA?
Antibiotic-resistant bacterial infection
Difficult to treat
🫀 Simple understanding
Infection that does not respond to common antibiotics.
⚠ Nursing focus
Hand hygiene
Isolation precautions
Correct antibiotic use
What is cellulitis?
Bacterial skin infection
Causes redness, swelling, heat
🫀 Simple understanding
Infection spreads in skin and soft tissue.
What is dementia?
Progressive loss of memory and cognition
Irreversible condition
🫀 Simple understanding
Brain function slowly declines over time.
⚠ Features
Memory loss
Confusion
Behaviour changes
What is Parkinson’s disease?
Degenerative disorder affecting movement
Dopamine deficiency in brain
🫀 Simple understanding
Brain loses control of smooth movement.
⚠ Signs
Tremor
Stiffness
Slow movement (bradykinesia)
What is a spinal cord injury?
Damage to spinal cord affecting movement/sensation
Can cause paralysis
🫀 Simple understanding
Nerve signals between brain and body are disrupted.
What is oxygen therapy used for?
Treats hypoxia (low oxygen levels)
Delivered via devices (nasal cannula, mask)
🫀 Simple understanding
Increases oxygen available to the lungs and blood.
⚠ Key point
Oxygen is a drug
Needs correct target saturation
Especially important in COPD patients
What are ABGs used for?
Measure oxygen, CO₂, and blood pH
Assess respiratory and metabolic status
🫀 Simple understanding
Shows how well lungs and kidneys are balancing oxygen and acid levels.
What are the main types of insulin?
Rapid-acting (meal time)
Short-acting
Intermediate-acting
Long-acting (background)
🫀 Simple understanding
Different insulins act at different speeds to control blood sugar.
What are complications of diabetes?
Kidney disease
Eye damage (retinopathy)
Nerve damage (neuropathy)
Heart disease
What is chemotherapy?
Drug treatment that kills cancer cells
Also affects healthy fast-growing cells
⚠ Side effects
Hair loss
Nausea
Low immunity (neutropenia)
What is neutropenia?
Low white blood cell count
Increased infection risk
🫀 Simple understanding
Body has weak immune defence.
What causes pressure ulcers?
Prolonged pressure on skin
Reduced blood flow to tissue
🫀 Simple understanding
Skin breaks down due to constant pressure.
What is polypharmacy?
Use of multiple medications
Common in older adults
⚠ Risk
Drug interactions
Falls
Confusion
What is inclusive nursing care?
Providing care that meets individual needs
Adapting communication and support
🫀 Simple understanding
Care is adjusted so everyone can understand and access it.
What is community nursing?
Healthcare provided outside hospitals
Includes home care and chronic disease management
🫀 Simple understanding
Supporting patients to live safely at home.
What is priority in trauma bleeding?
Stop bleeding
Maintain circulation
Prevent shock
What is perforated diverticulitis?
Rupture of inflamed bowel pouches
Causes infection in abdomen (peritonitis)
🫀 Simple understanding
A hole forms in the bowel → contents leak → severe infection.
🚨 Signs
Severe abdominal pain
Fever
Rigid abdomen
Sepsis risk
What are the main oxygen delivery devices?
Nasal cannula
Simple face mask
Venturi mask
Non-rebreather mask
When is a nasal cannula used?
For mild oxygen support (low to moderate oxygen needs).
Why is a Venturi mask important?
It delivers a fixed oxygen concentration, important for COPD patients.
When is a non-rebreather mask used?
In emergencies where high oxygen levels are needed (e.g. severe hypoxia).
What are normal oxygen saturation targets?
Usually 94–98%
What is the oxygen target for COPD patients?
88–92%