Controlled Substances

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Last updated 10:59 PM on 7/23/26
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10 Terms

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Schedule I

  • Illegal and not sold in Pharmacies

  • Ex: Heroine, LSD, GHP, Marijuana, PCP, Ecstacy

2
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Schedule II

  • Highest potential for misuse and physiological dependence or addiction

  • Most stringent requirements in pharmacy

  • No refills allowed

  • Rx expires 90 days after written

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Schedule II Opioid Medications

  • Hydrocodone combinations (Lortab, Norco, Tussionex, Vicoprofen)

  • Fentanyl (Duragesic, Actiq, Abstral, Lazanda, Fentora)

  • Hydromorphone (Dilaudid)

  • Meperidine (Demerol)

  • Morphine sulfate (MS Contin, Oramorph, Kadian, Avinza)

  • Methadone (Dolophine)

  • Oxycodone (OxyContin, Roxicodone)

  • Oxycodone combinations (Percocet)

  • Single-ingredient codeine products

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Schedule II Stimulant Medications

  • Amphetamine/dextroamphetamine combos (Adderall)

  • Dextroamphetamine (Dexedrine)

  • Methylphenidate (Concerta, Ritalin, Methylin, Daytrana, Metadate, Quillivant XR)

  • Dexmethylphenidate (Focalin)

  • Lisdexamfetamine (Vyvanse)

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Schedule III

  • Less misuse and addiction potential than Schedule II medications

  • 5 refills allowed

  • Rx expires after 6 months

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Schedule III Medications

  • Buprenorphine (Suboxone, Subtex)

  • Acetaminophen/codeine (Tylenol #3)

  • Butalbital/aspirin (Fiorinal)

  • Testosterone (AndroGel, Androderm, Depo-Testosterone)

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Schedule IV

  • Less misuse and addiction potential than Schedule II and III medications

  • 5 refills allowed,

  • Rx expires after 6 months

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Schedule IV Medications

  • Phentermine (Adipex-P)

  • Alprazolam (Xanax)

  • Clonazepam (Klonopin)

  • Lorazepam (Ativan)

  • Diazepam (Valium)

  • Temazepam (Restoril)

  • Triazolam (Halcion)

  • Carisoprodol (Soma)

  • Modafinil (Provigil)

  • Zolpidem (Ambien)

  • Zaleplon (Sonata)

  • Eszopiclone (Lunesta)

  • Phenobarbital (Luminal)

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Schedule V

  • Lowest misuse potential of all controlled substances

  • Some states allow certain C-V medications to be dispensed without a prescription

  • Refills up to the prescriber

  • Rx expires after 6 months

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Schedule V Medications

  • Codeine combinations with no more than 200 mg codeine/100 ml (Robitussin AC)

  • Dipheenoxylate/atropine combos with no more than 2.5 mg diphenoxylate and not less than 25 mg atropine per dosage unit (Lomotil)

  • Pregabalin (Lyrica)

  • Lacosamide (Vimpat)