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Burns
What are the three main classifications of burns?
Superficial (1st degree), partial-thickness (2nd degree), full-thickness (3rd degree)
What is the hallmark of a superficial burn?
Redness, pain, no blisters (e.g., sunburn)
How do partial-thickness burns present?
Red, painful, and blistered
What is the appearance of full-thickness burns?
White, charred, painless due to nerve damage
What is the Rule of Nines?
A method to estimate total body surface area (TBSA) affected by burns
What is the most critical initial treatment for severe burns?
Fluid resuscitation, typically using the Parkland formula (4 mL/kg per %TBSA)
What is the Parkland formula for burns?
4 mL/kg per %TBSA, half given in the first 8 hours, remainder in the next 16 hours
What topical antibiotic is commonly used in burn management?
Silver sulfadiazine and topical Bacitracin
What is the greatest risk for burn victims?
Infection
When should you consider transferring a burn patient to a burn center?
When TBSA >10%, involvement of face, hands, feet, genitals, or full-thickness burns
What lab abnormalities are common in burn patients?
Hypovolemia, hyperkalemia, metabolic acidosis
How are inhalation injuries associated with burns treated?
Airway management with oxygen or intubation as necessary
What is the indication for escharotomy in burn patients?
To relieve pressure from circumferential burns and restore circulation
Cellulitis
What is the most common pathogen causing cellulitis?
Group A Streptococcus (Strep pyogenes)
What are the typical signs of cellulitis?
Redness, swelling, warmth, and tenderness of the skin
What is the first-line treatment for uncomplicated cellulitis?
Oral antibiotics like cephalexin or dicloxacillin
What distinguishes cellulitis from erysipelas?
Erysipelas involves more superficial layers with sharply demarcated edges
What is the key risk factor for developing cellulitis?
Skin break or injury such as a cut or insect bite
What imaging is used if an abscess or deep infection is suspected with cellulitis?
Ultrasound or CT scan
How do you manage purulent cellulitis?
Empiric antibiotic therapy targeting MRSA (e.g., clindamycin, doxycycline)
What condition must be ruled out in rapidly progressing cellulitis?
Necrotizing fasciitis
What population is at high risk for recurrent cellulitis?
Patients with chronic lymphedema or venous insufficiency
What is the role of IV antibiotics in cellulitis?
For severe cases or failure of oral antibiotics
How can you prevent recurrent cellulitis in at-risk patients?
Skin hygiene, weight loss, compression therapy for edema
What complication can arise from untreated cellulitis?
Sepsis or deep tissue abscess
What is the duration of antibiotic therapy for cellulitis?
Typically 5-10 days, but longer for complicated cases
Dermatologic Neoplasms
What is the most common type of skin cancer?
Basal cell carcinoma
What is the most common risk factor for skin cancer?
UV light exposure
How does basal cell carcinoma typically present?
Pearly, raised lesion with telangiectasia, often on sun-exposed areas
What is the main distinguishing feature of squamous cell carcinoma?
Firm, scaly, red papules or plaques, often with ulceration
What is the ABCDE rule for melanoma?
Asymmetry, Border irregularity, Color variation, Diameter >6mm, Evolving
What is the preferred treatment for basal cell carcinoma?
Surgical excision or Mohs micrographic surgery
What is the best initial diagnostic step for suspected melanoma?
Excisional biopsy with narrow margins
What is the treatment for localized melanoma?
Wide excision with sentinel lymph node biopsy
What type of biopsy should be avoided in melanoma?
Shave biopsy due to inadequate depth
What is the role of immunotherapy in advanced melanoma?
Checkpoint inhibitors (e.g., nivolumab) improve survival in metastatic disease
What is the most common site of metastasis for melanoma?
Lymph nodes and distant skin sites
What is the primary treatment for squamous cell carcinoma?
Excision with clear margins
How is actinic keratosis related to squamous cell carcinoma?
Actinic keratosis is a precancerous lesion that can progress to squamous cell carcinoma
Epidermal Inclusion Cyst
What is an epidermal inclusion cyst?
A benign cyst containing keratinous material
How does an epidermal inclusion cyst present?
Mobile, firm, subcutaneous nodule often with a central punctum
What is the treatment for asymptomatic epidermal inclusion cysts?
Observation unless inflamed or symptomatic
What is the definitive treatment for an inflamed or infected cyst?
Incision and drainage followed by excision after inflammation resolves
What complication can arise from an untreated infected epidermal inclusion cyst?
Abscess formation
How do you differentiate an epidermal inclusion cyst from a lipoma?
Cysts have a central punctum and are usually firmer, while lipomas are soft and lobulated
What is the recurrence rate after excision of an epidermal inclusion cyst?
Low if completely excised, including the cyst wall
What causes an epidermal inclusion cyst?
Blockage of a hair follicle or skin trauma
What is the most common location for epidermal inclusion cysts?
Face, neck, and trunk
What is the histological finding in an epidermal inclusion cyst?
A cyst lined by squamous epithelium containing lamellated keratin
What is the appearance of a ruptured epidermal inclusion cyst?
Painful, erythematous nodule with cheesy white discharge
What is the best treatment for a ruptured cyst with secondary infection?
Incision, drainage, and oral antibiotics
How can epidermal inclusion cysts be prevented?
There is no reliable prevention method, but avoiding trauma may help reduce risk
Hidradenitis Suppurativa
What is hidradenitis suppurativa?
A chronic inflammatory condition of the apocrine glands leading to abscesses, scarring, and sinus tracts
What are common sites of hidradenitis suppurativa?
Axillae, groin, perineal, and inframammary areas
What is the initial treatment for mild hidradenitis suppurativa?
Topical clindamycin or oral antibiotics like tetracyclines
What is the primary risk factor for hidradenitis suppurativa?
Obesity, smoking, and family history
What is the Hurley staging system for?
It classifies the severity of hidradenitis suppurativa into three stages
What is the treatment for moderate to severe hidradenitis suppurativa?
Oral antibiotics, anti-TNF agents (e.g., infliximab), or surgical excision
What is the role of lifestyle changes in managing hidradenitis suppurativa?
Weight loss and smoking cessation can help reduce flares
What complication can arise from untreated hidradenitis suppurativa?
Formation of sinus tracts and severe scarring
What is the role of surgery in hidradenitis suppurativa?
Wide excision of involved skin in advanced cases
How do you differentiate hidradenitis suppurativa from other skin infections?
Chronicity, location, and the presence of sinus tracts and multiple abscesses
What is the most common presentation of hidradenitis suppurativa?
Painful nodules, abscesses, and draining sinus tracts in apocrine gland-bearing areas
What systemic treatments are considered for hidradenitis suppurativa?
Biologic agents like adalimumab in severe cases
What is the recurrence rate of hidradenitis suppurativa after surgery?
High, particularly in patients who continue smoking or do not lose weight
Lipoma
What is a lipoma?
A benign tumor of adipose tissue
How does a lipoma typically present?
Soft, mobile, and painless subcutaneous mass
What is the treatment for symptomatic lipoma?
Surgical excision
What imaging is used to confirm a lipoma?
Ultrasound or MRI if deep or atypical
How can you differentiate a lipoma from a sarcoma?
Lipomas are typically soft and painless, while sarcomas may be firmer and painful
What is the recurrence rate of a lipoma after excision?
Low if completely excised
What is the histological appearance of a lipoma?
Well-circumscribed mass of mature adipocytes
What is the most common location for lipomas?
Trunk, shoulders, and neck
What complication can arise from a rapidly growing lipoma?
Rarely, a liposarcoma, though most lipomas are benign
What is the usual size range of lipomas?
Typically less than 5 cm, but they can grow larger
What is the most common treatment for multiple lipomas?
Observation unless symptomatic or concerning features present
What are the concerning features of a lipoma that warrant further investigation?
Rapid growth, pain, or firmness
What is the genetic condition associated with multiple lipomas?
Familial multiple lipomatosis
Pressure Ulcer
What are the stages of pressure ulcers?
Stage 1: Non-blanchable erythema, Stage 2: Partial-thickness skin loss, Stage 3: Full-thickness skin loss, Stage 4: Full-thickness tissue loss with exposed bone, tendon, or muscle
What is the most common site for pressure ulcers?
Bony prominences such as the sacrum, heels, and hips
What is the primary cause of pressure ulcers?
Prolonged pressure leading to ischemia of soft tissues
What is the best initial management for a stage 1 pressure ulcer?
Pressure relief and skin protection with barrier creams
What is the gold standard for diagnosing the extent of a pressure ulcer?
Clinical examination, but MRI can be used to assess deeper tissue involvement
How are stage 3 and 4 pressure ulcers treated?
Debridement, wound care, and possibly surgical intervention
What are the risk factors for developing pressure ulcers?
Immobility, poor nutrition, and incontinence
What role do nutritional supplements play in pressure ulcer prevention?
Protein and vitamin C supplementation can aid in healing
What complication can result from an untreated stage 4 pressure ulcer?
Osteomyelitis or sepsis
What is the key prevention strategy for pressure ulcers in bedridden patients?
Regular repositioning and use of pressure-relieving mattresses
What is the role of negative pressure wound therapy in pressure ulcers?
It can help promote healing in deeper ulcers
How is infection in a pressure ulcer diagnosed?
Wound culture and biopsy if osteomyelitis is suspected
What is the primary complication of pressure ulcers in elderly patients?
High risk of infection leading to morbidity and mortality
Dermatologic Procedures
What is the purpose of aspiration of a seroma or hematoma?
To drain accumulated fluid and prevent infection or dehiscence