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What is intoxication dependent on
Dosage
4 stages of marijuana intoxication
1: Buzz, brief periods of light headedness and dizziness 2: High, euphoria, laughter 3: stoned, clam relaxation 4: “Come-down”
What are CB1 receptors responsible for causing in marijuana
increasing blood flow to skin (flushing) increasing HR, increase hunger
Decreases reaction time affecting cognitive functions & psychomotor performance
Affect memory processing
What pathway do cannabinoid receptors activate
Are reinforcing due to activation of mesolimbic DA pathway
Increases VTA firing and DA release in NA